Zobrazeno 1 - 10
of 512
pro vyhledávání: '"MESH: Cell Cycle"'
Autor:
Mehdi Totonchi, Mehri Mashayekhi, Ken McElreavey, Navid Almadani, Anu Bashambou, Arvand Akbari, Kimiya Padidar, Najmeh Salehi, Mohammad Ali Sadighi Gilani
Publikováno v:
Human Reproduction
Human Reproduction, 2021, 36 (4), pp.1134-1145. ⟨10.1093/humrep/deaa362⟩
Human Reproduction, Oxford University Press (OUP), 2021, 36 (4), pp.1134-1145. ⟨10.1093/humrep/deaa362⟩
Human Reproduction, 2021, 36 (4), pp.1134-1145. ⟨10.1093/humrep/deaa362⟩
Human Reproduction, Oxford University Press (OUP), 2021, 36 (4), pp.1134-1145. ⟨10.1093/humrep/deaa362⟩
STUDY QUESTIONCan whole-exome sequencing (WES) reveal a shared pathogenic variant responsible for primary gonadal failure in both male and female patients from a consanguineous family?SUMMARY ANSWERPatients with primary ovarian insufficiency (POI) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbb6fadc8926a4bf1f45ebf363194ab
https://doi.org/10.1093/humrep/deaa362
https://doi.org/10.1093/humrep/deaa362
Autor:
Guillaume Jouret, Solveig Heide, Arthur Sorlin, Laurence Faivre, Sandra Chantot‐Bastaraud, Claire Beneteau, Marie Denis‐Musquer, Peter D. Turnpenny, Charles Coutton, Gaëlle Vieville, Julien Thevenon, Austin Larson, Florence Petit, Elise Boudry, Thomas Smol, Bruno Delobel, Bénédicte Duban‐Bedu, Chiara Fallerini, Francesca Mari, Caterina Lo Rizzo, Alessandra Renieri, Jean‐Hubert Caberg, Anne‐Sophie Denommé‐Pichon, Frédéric Tran Mau‐Them, Isabelle Maystadt, Thomas Courtin, Boris Keren, Linda Mouthon, Perrine Charles, Silvestre Cuinat, Bertrand Isidor, Philippe Theis, Christian Müller, Marizela Kulisic, Seval Türkmen, Daniel Stieber, Dominique Bourgeois, Emmanuel Scalais, Barbara Klink
Publikováno v:
Clinical Genetics
Clinical Genetics, 2022, 102 (2), pp.117-122. ⟨10.1111/cge.14141⟩
Clinical Genetics, 2022, 102 (2), pp.117-122. ⟨10.1111/cge.14141⟩
International audience; BRD4 is part of a multiprotein complex involved in loading the cohesin complex onto DNA, a fundamental process required for cohesin-mediated loop extrusion and formation of Topologically Associating Domains. Pathogenic variati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef656e7edd72467b3c068c87f79974e9
https://pubmed.ncbi.nlm.nih.gov/35470444
https://pubmed.ncbi.nlm.nih.gov/35470444
Autor:
Ira Fleming, Carolyn Winston, Benjamin Kruft, Alex K. Shalek, Wolfram Goessling, Satdarshan P.S. Monga, Florian Mueller, Sungjin Ko, Udayan Apte, Chad Walesky, Kellie E. Kolb, Jake Henderson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications, 2020, 11 (1), pp.5785. ⟨10.1038/s41467-020-19558-3⟩
Nature Communications
Nature Communications, 2020, 11 (1), pp.5785. ⟨10.1038/s41467-020-19558-3⟩
The liver plays a central role in metabolism, protein synthesis and detoxification. It possesses unique regenerative capacity upon injury. While many factors regulating cellular proliferation during liver repair have been identified, the mechanisms b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b098b526816baaea3f6aa2942d407e5
https://doaj.org/article/19ae1c964a6645e69ee2804af9f1cfd1
https://doaj.org/article/19ae1c964a6645e69ee2804af9f1cfd1
Autor:
de Krijger, Inge, Föhr, Bastian, Pérez, Santiago Hernández, Vincendeau, Estelle, Serrat, Judit, Thouin, Alexander Marc, Susvirkar, Vivek, Lescale, Chloé, Paniagua, Inés, Hoekman, Liesbeth, Kaur, Simranjeet, Altelaar, Maarten, Deriano, Ludovic, Faesen, Alex C, Jacobs, Jacqueline J L, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.5421. ⟨10.1038/s41467-021-25724-y⟩
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, 12(1). Nature Publishing Group
Nature Communications, 2021, 12 (1), pp.5421. ⟨10.1038/s41467-021-25724-y⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-25724-y⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.5421. ⟨10.1038/s41467-021-25724-y⟩
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, 12(1). Nature Publishing Group
Nature Communications, 2021, 12 (1), pp.5421. ⟨10.1038/s41467-021-25724-y⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-25724-y⟩
MAD2L2 (REV7) plays an important role in DNA double-strand break repair. As a member of the shieldin complex, consisting of MAD2L2, SHLD1, SHLD2 and SHLD3, it controls DNA repair pathway choice by counteracting DNA end-resection. Here we investigated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0eef28d1f10f82de63f851b152c960
https://hdl.handle.net/21.11116/0000-000A-7D73-921.11116/0000-000A-7D6F-F
https://hdl.handle.net/21.11116/0000-000A-7D73-921.11116/0000-000A-7D6F-F
Autor:
Zindel, Diana, Mensat, Patrick, Vol, Claire, Homayed, Zeinab, Charrier-Savournin, Fabienne, Trinquet, Eric, Banères, Jean-Louis, Pin, Jean-Philippe, Pannequin, Julie, Roux, Thomas, Dupuis, Elodie, Prézeau, Laurent, Charrier‐Savournin, Fabienne, Banères, Jean‐Louis, Pin, Jean‐Philippe
Publikováno v:
FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (7), pp.e21668. ⟨10.1096/fj.202002159R⟩
FASEB Journal, 2021, 35 (7), pp.e21668. ⟨10.1096/fj.202002159R⟩
FASEB Journal, Federation of American Society of Experimental Biology, 2021, 35 (7), pp.e21668. ⟨10.1096/fj.202002159R⟩
FASEB Journal, 2021, 35 (7), pp.e21668. ⟨10.1096/fj.202002159R⟩
International audience; The Hippo pathway is an evolutionarily conserved kinase cascade involved in the control of tissue homeostasis, cellular differentiation, proliferation, and organ size, and is regulated by cell-cell contact, apical cell polarit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d116edd5ecc7a3517e908ffca203be02
https://hal.archives-ouvertes.fr/hal-03382626
https://hal.archives-ouvertes.fr/hal-03382626
Autor:
Bruno Ragazzon, Jean-Christophe Pointud, Houda Tabbal, Pierre Val, Igor Tauveron, Coralie Drelon, M. Batisse-Lignier, Cyril Djari, Stéphanie Rodriguez, Anne-Marie Lefrançois-Martinez, Amandine Septier, Jérôme Bertherat, Guillaume Assié, Isabelle Sahut-Barnola, Mickael Mathieu, Antoine Martinez
Publikováno v:
British Journal of Cancer
British Journal of Cancer, Cancer Research UK, 2019, 121 (5), pp.384-394. ⟨10.1038/s41416-019-0538-y⟩
British Journal of Cancer, 2019, 121 (5), pp.384-394. ⟨10.1038/s41416-019-0538-y⟩
British Journal of Cancer, Cancer Research UK, 2019, 121 (5), pp.384-394. ⟨10.1038/s41416-019-0538-y⟩
British Journal of Cancer, 2019, 121 (5), pp.384-394. ⟨10.1038/s41416-019-0538-y⟩
International audience; BACKGROUND: EZH2 is overexpressed and associated with poor prognosis in adrenocortical carcinoma (ACC) and its inhibition reduces growth and aggressiveness of ACC cells in culture. Although EZH2 was identified as the methyltra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e8aeb4b82b5deb9b1796239f7afa18
https://doi.org/10.1038/s41416-019-0538-y
https://doi.org/10.1038/s41416-019-0538-y
Autor:
Loelia Babin, Caroline Demangel, Hélène Lenden-Hasse, Ludovic Deriano, Ludivine Baron, Erika Brunet, José Yélamos, Marie Bedora-Faure, Wei Yu, Chloé Lescale
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.5239. ⟨10.1038/s41467-020-19060-w⟩
Nature Communications, 2020, 11 (1), pp.5239. ⟨10.1038/s41467-020-19060-w⟩
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.5239. ⟨10.1038/s41467-020-19060-w⟩
Nature Communications, 2020, 11 (1), pp.5239. ⟨10.1038/s41467-020-19060-w⟩
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
The alternative non-homologous end-joining (NHEJ) pathway promotes DNA double-strand break (DSB) repair in cells deficient for NHEJ or homologous recombination, suggesting that it operates at all stages of the cell cycle. Here, we use an approach in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3732515aa216a36cf4ec687e59a5511b
https://hal-pasteur.archives-ouvertes.fr/pasteur-03262335/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03262335/document
Autor:
Ada Nowosad, Caroline Callot, Carine Joffre, Arnaud Besson, Stéphane Manenti, Patrice Codogno, Pauline Jeannot, Justine Creff, Renaud T. Perchey
Publikováno v:
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2020, 22 (9), pp.1076-1090. ⟨10.1038/s41556-020-0554-4⟩
Nature Cell Biology, Nature Publishing Group, 2020, 22 (9), pp.1076-1090. ⟨10.1038/s41556-020-0554-4⟩
International audience; Autophagy is a catabolic process whereby cytoplasmic components are degraded within lysosomes, allowing cells to maintain energy homeostasis during nutrient depletion. Several studies reported that the CDK inhibitor p27Kip1 pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94e1a946c85d0a3567d7dd5c51cec58
https://hal.archives-ouvertes.fr/hal-02989025
https://hal.archives-ouvertes.fr/hal-02989025
Autor:
Ian D. Waddell, Robert W. Sobol, Kate M. Smith, Justin L. Roncaioli, Felipe da Veiga Leprevost, Song My Hoang, Dattatreya Mellacharevu, Dominique Ray-Gallet, Michelle L. Lynskey, Roderick J. O’Sullivan, Ragini Bhargava, Jonathan Barroso-González, Nicole Kaminski, Geneviève Almouzni, Anne R. Wondisford, Jianfeng Li, Donald J. Ogilvie, Alexey I. Nesvizhskii, Dominic I. James, Callen T. Wallace, Simon C. Watkins, Laura García-Expósito
Publikováno v:
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, Nature Publishing Group, 2020, 27 (12), pp.1152-1164. ⟨10.1038/s41594-020-0512-7⟩
Nature Structural & Molecular Biology
Nature Structural and Molecular Biology, 2020, 27 (12), pp.1152-1164. ⟨10.1038/s41594-020-0512-7⟩
Nat Struct Mol Biol
Nature Structural and Molecular Biology, Nature Publishing Group, 2020, 27 (12), pp.1152-1164. ⟨10.1038/s41594-020-0512-7⟩
Nature Structural & Molecular Biology
Nature Structural and Molecular Biology, 2020, 27 (12), pp.1152-1164. ⟨10.1038/s41594-020-0512-7⟩
Nat Struct Mol Biol
International audience; The synthesis of poly(ADP-ribose) (PAR) reconfigures the local chromatin environment and recruits DNA-repair complexes to damaged chromatin. PAR degradation by poly(ADP-ribose) glycohydrolase (PARG) is essential for progressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d45f0c33f255ca7323659e74359498
https://hal.sorbonne-universite.fr/hal-03138406
https://hal.sorbonne-universite.fr/hal-03138406
Autor:
Corinne Abbadie, Erwan Goy
Publikováno v:
médecine/sciences
médecine/sciences, 2018, 34 (3), pp.223-230. ⟨10.1051/medsci/20183403010⟩
médecine/sciences, 2018, 34 (3), pp.223-230. ⟨10.1051/medsci/20183403010⟩
International audience; When ageing, cells profoundly reprogram to enter a state called senescence. Although the link between senescence and cancer is well established, the nature of this link remains unclear and debated. We will describe in this art
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7123b6b09908c9fc837292df2b368d
https://hal.science/hal-02542700
https://hal.science/hal-02542700