Prioritization of mycotoxins based on mutagenicity and carcinogenicity evaluation using combined in silico QSAR methods

Autor: Pierre Lemée, Valérie Fessard, Denis Habauzit

Publikováno v: Environmental Pollution
Environmental Pollution, 2023, 323, pp.121284. ⟨10.1016/j.envpol.2023.121284⟩

International audience; Mycotoxins and their metabolites are a family of compounds that contains a great diversity of both structure and biological properties. Information on their toxicity is spread within several databases and in scientific literat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7438940b31e9934c3cfb87162b30d533
https://doi.org/10.1016/j.envpol.2023.121284

Lipid metabolism and Calcium signaling in epithelial ovarian cancer

Autor: Aurélie Chantôme, Marie Potier-Cartereau, Sana Kouba, Caroline Goupille, Christophe Vandier, Lobna Ouldamer, Céline Garcia, Delphine Fontaine

Publikováno v: Cell Calcium
Cell Calcium, Elsevier, 2019, 81, pp.38-50. ⟨10.1016/j.ceca.2019.06.002⟩
Cell Calcium, 2019, 81, pp.38-50. ⟨10.1016/j.ceca.2019.06.002⟩

International audience; Epithelial Ovarian cancer (EOC) is the deadliest gynecologic malignancy and represents the fifth leading cause of all cancer-related deaths in women. The majority of patients are diagnosed at an advanced stage of the disease t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a6f3c4dd3dedbfaae042d54c8fd219
https://hal.archives-ouvertes.fr/hal-02954678/document

Functional role of Kv1.1 and Kv1.3 channels in the neoplastic progression steps of three cancer cell lines, elucidated by scorpion peptides

Autor: Wassim Moslah, Soumaya Souid, Jed Jebali, Dorra Aissaoui, Houcemeddine Othman, Mohamed Elayeb, Saoussen Mlayah-Bellalouna, José Luis, Zaineb Abdelkafi-Koubaa, Khadija Essafi-Benkhadir, Naziha Marrakchi, Najet Srairi-Abid

Publikováno v: International Journal of Biological Macromolecules
International Journal of Biological Macromolecules, 2018, 111, pp.1146-1155. ⟨10.1016/j.ijbiomac.2018.01.144⟩
International Journal of Biological Macromolecules, Elsevier, 2018, 111, pp.1146-1155. ⟨10.1016/j.ijbiomac.2018.01.144⟩

International audience; Voltage-gated potassium (Kv) channels are known to play a pivotal role in the progression of various cancer types and considered as new targets for designing anti-cancer therapy. However, the fact that many Kv channels are exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9397ccddf29007935bd17cae2ee4bb23
https://hal-amu.archives-ouvertes.fr/hal-01765752

ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

Autor: Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, Bièche, Ivan, Marchand, Nathalie, De Launoit, Yvan, Tulasne, David, Chotteau-Lelièvre, Anne

Publikováno v: Breast Cancer Research
Breast Cancer Research, 2018, 20 (1), pp.73. ⟨10.1186/s13058-018-0992-0⟩
Breast Cancer Research, BioMed Central, 2018, 20, ⟨10.1186/s13058-018-0992-0⟩
Breast Cancer Research, BioMed Central, 2018, 20 (1), pp.73. ⟨10.1186/s13058-018-0992-0⟩
Breast Cancer Research, Vol 20, Iss 1, Pp 1-18 (2018)
Breast Cancer Research : BCR
Breast Cancer Research, BioMed Central, 2018, 20 (1), ⟨10.1186/s13058-018-0992-0⟩

Background The ETS transcription factor ETV4 is involved in the main steps of organogenesis and is also a significant mediator of tumorigenesis and metastasis, such as in breast cancer. Indeed, ETV4 is overexpressed in breast tumors and is associated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c1bdbc6fa24e5fe30ccd6083e8937deb
https://hal.science/hal-02391607

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

Autor: Dustin G. Brown, Tove Hultman, Judith Weisz, H. Kim Lyerly, Paola A. Marignani, Ann-Karin Olsen, Rabindra Roy, Kim Moorwood, Masoud H. Manjili, Monica Vaccari, Jesse Roman, Hasiah Ab Hamid, Kalan R. Prudhomme, Periyadan K. Krishnakumar, Chenfang Dong, Tiziana Guarnieri, Leandro S. D'Abronzo, Gloria M. Calaf, Amelia K Charles, Emanuela Corsini, Yunus A. Luqmani, Graeme Williams, Louis Vermeulen, Pankaj Vadgama, Sarah N Bay, Véronique Maguer-Satta, Sabine A. S. Langie, Christian C. Naus, Le Jian, Gladys N. Nangami, Lorenzo Memeo, Stephanie C. Casey, Thomas Sanderson, Takemi Otsuki, Nichola Cruickshanks, William H. Bisson, Sudjit Luanpitpong, Jonathan Whitfield, Ahmed Lasfar, Yon Rojanasakul, A. Ivana Scovassi, Shelley A. Harris, Ferdinando Chiaradonna, Richard Ponce-Cusi, Gregory T. Wolf, Valérian Dormoy, Roslida Abd Hamid, Hyun Ho Park, Matilde E. Lleonart, William K. Decker, Maria Romano, Leroy Lowe, Fabio Marongiu, Jan Vondráček, Chiara Mondello, Luc Leyns, Josiah Ochieng, Pratima Nangia-Makker, Edward A. Ratovitski, Zhiwei Hu, Jayadev Raju, Hemad Yasaei, Rafaela Andrade-Vieira, Jordan Woodrick, Hideko Sone, Harini Krishnan, W. Kimryn Rathmell, Andrew Collins, Luoping Zhang, Barry J. Barclay, Amaya Azqueta, Laura Soucek, Marc A. Williams, David O. Carpenter, Roberta Palorini, Rita Nahta, Juan Fernando Martinez-Leal, Firouz Darroudi, Rita Dornetshuber-Fleiss, James E. Klaunig, Elizabeth P. Ryan, Qiang Shawn Cheng, Arthur Berg, Andrew Ward, Gudrun Koppen, Tao Chen, Petr Heneberg, Michael Gilbertson, Amedeo Amedei, Sakina E. Eltom, Ezio Laconi, Joseph Christopher, Hiroshi Kondoh, Neetu Singh, Danielle J Carlin, Marion Chapellier, Michalis V. Karamouzis, Rekha Mehta, Tae-Jin Lee, Annamaria Colacci, Venkata S. Sabbisetti, Mark Wade, Micheline Kirsch-Volders, Patricia Ostrosky-Wegman, Isabelle R. Miousse, Patricia A. Thompson, Philippa D. Darbre, Frederik J. van Schooten, Sofia Pavanello, Igor Koturbash, Binhua P. Zhou, Ranjeet Kumar Sinha, Anna C. Salzberg, Mahara Valverde, Fahd Al-Mulla, Julia Kravchenko, Nicole Kleinstreuer, Carolyn J. Baglole, Menghang Xia, Samira A. Brooks, Amancio Carnero, Gunnar Brunborg, Sandra S. Wise, Daniel C. Koch, John Pierce Wise, Rabeah Al-Temaimi, Laetitia Gonzalez, Lisa J. McCawley, R. Brooks Robey, Gary S. Goldberg, Thierry Massfelder, Linda S M Gulliver, Olugbemiga Ogunkua, Emilio Rojas, Eun-Yi Moon, Lin Li, Silvana Papagerakis, Nik van Larebeke, Adela Lopez de Cerain Salsamendi, Staffan Eriksson, Simona Romano, Dean W. Felsher, Paramita M. Ghosh, Karine A. Cohen-Solal, Paul Dent, Jun Sun, Carmen Blanco-Aparicio, Riccardo Di Fiore, Chia-Wen Hsu, Mahin Khatami, Kannan Badri Narayanan, Francis Martin, Colleen S. Curran, Dale W. Laird, William H. Goodson, Abdul Manaf Ali, Valerie Odero-Marah, Michael J. Gonzalez, Renza Vento, Liang Tzung Lin, Clement G. Yedjou, Hosni Salem, Hsue-Yin Hsu, Zhenbang Chen, Nuzhat Ahmed, Gerard Wagemaker, Sandra Ryeom, Stefano Forte, Debasish Roy, Nancy B. Kuemmerle, Robert C. Castellino, Po Sing Leung, Wilhelm Engström

Publikováno v: Carcinogenesis, 36 Suppl 1, S254-S296. Oxford University Press
Carcinogenesis
Carcinogenesis, Oxford University Press (OUP), 2015, 36 (Suppl 1), pp.S254-96. ⟨10.1093/carcin/bgv039⟩
Carcinogenesis, 2015, 36 (Suppl 1), pp.S254-96. ⟨10.1093/carcin/bgv039⟩
Digital.CSIC. Repositorio Institucional del CSIC
instname

Goodson, William H. et al.
© The Author 2015. Lifestyle factors are responsible for a considerable portion of cancer incidence worldwide, but credible estimates from the World Health Organization and the International Agency for Research on Can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5823ab67c1d978d35e01104f2396538
https://doi.org/10.1093/carcin/bgv039