Výsledky vyhledávání - "MESH: Candida glabrata"

Introns Protect Eukaryotic Genomes from Transcription-Associated Genetic Instability

Autor: Vincent Géli, Ana Rita Grosso, Guilhem Janbon, Emeline Coleno, Sérgio F. de Almeida, Amandine Bonnet, Adrien Presle, Sree Rama Chaitanya Sridhara, Abdessamad El-Kaoutari, Benoit Palancade

Publikováno v: Molecular Cell
Molecular Cell, 2017, 67 (4), pp.608-621.e6. ⟨10.1016/j.molcel.2017.07.002⟩
Molecular Cell, Elsevier, 2017, 67 (4), pp.608-621.e6. ⟨10.1016/j.molcel.2017.07.002⟩

International audience; Transcription is a source of genetic instability that can notably result from the formation of genotoxic DNA:RNA hybrids, or R-loops, between the nascent mRNA and its template. Here we report an unexpected function for introns

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f673dd6bd7dced7f5f95449282df3bf5

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Biofilm formation in Candida glabrata: What have we learnt from functional genomics approaches?

Autor: Guilhem Janbon, Christophe d'Enfert

Publikováno v: FEMS Yeast Research
FEMS Yeast Research, Oxford University Press (OUP), 2015, 16 (1), pp.fov111. ⟨10.1093/femsyr/fov111⟩
FEMS Yeast Research, 2015, 16 (1), pp.fov111. ⟨10.1093/femsyr/fov111⟩

International audience; Biofilms are a source of therapeutic failures because of their intrinsic tolerance to antimicrobials. Candida glabrata is one of the pathogenic yeasts that is responsible for life-threatening disseminated infections and able t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caf9e0ffdafb49e35929afe6d0a4a0e0
https://hal-pasteur.archives-ouvertes.fr/pasteur-01517804/document

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Genome-wide replication landscape of Candida glabrata

Autor: Cyril Saguez, Christiane Bouchier, Romain Koszul, Stéphane Descorps-Declère, Guy-Franck Richard, Laurence Ma, Martial Marbouty, Thomas Rolland, Bernard Dujon, Axel Cournac, Ivan Moszer

Publikováno v: BMC Biology
BMC Biology, BioMed Central, 2015, 13, pp.69. ⟨10.1186/s12915-015-0177-6⟩
BMC Biology, 2015, 13, pp.69. ⟨10.1186/s12915-015-0177-6⟩
BMC Biology, BioMed Central, 2015, 13 (1), pp.69. <10.1186/s12915-015-0177-6>

Background The opportunistic pathogen Candida glabrata is a member of the Saccharomycetaceae yeasts. Like its close relative Saccharomyces cerevisiae, it underwent a whole-genome duplication followed by an extensive loss of genes. Its genome contains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15924fd36aa0e0951802472bb32655b0
https://pubmed.ncbi.nlm.nih.gov/26329162

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Of mice, flies--and men? Comparing fungal infection models for large-scale screening efforts

Autor: Martin E. A. Richter, Ekkehard Hiller, Bernhard Hube, Lydia Kasper, Sascha Brunke, Dominique Ferrandon, Christophe d'Enfert, Jessica Quintin, Steffen Rupp, Karl Kuchler, Ilse D. Jacobsen, Tobias Schwarzmüller

Publikováno v: Disease Models & Mechanisms
Disease Models & Mechanisms, Cambridge Company of Biologists, 2015, 8 (5), pp.473-486. ⟨10.1242/dmm.019901⟩
Disease Models and Mechanisms 5 (8), 473-486. (2015)
Disease Models & Mechanisms, Vol 8, Iss 5, Pp 473-486 (2015)
Disease Models & Mechanisms, 2015, 8 (5), pp.473-486. ⟨10.1242/dmm.019901⟩

Studying infectious diseases requires suitable hosts for experimental in vivo infections. Recent years have seen the advent of many alternatives to murine infection models. However, the use of non-mammalian models is still controversial because it is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505ec6b2e629f1b37c9db7f13916ea47
https://pubmed.ncbi.nlm.nih.gov/25786415

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Role of Dectin-2 for Host Defense against Systemic Infection with Candida glabrata

Autor: Daniela C, Ifrim, Judith M, Bain, Delyth M, Reid, Marije, Oosting, Ineke, Verschueren, Neil A R, Gow, J Han, van Krieken, Gordon D, Brown, Bart-Jan, Kullberg, Leo A B, Joosten, Jos W M, van der Meer, Frank, Koentgen, Lars P, Erwig, Jessica, Quintin, Mihai G, Netea

Publikováno v: Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2014, 82 (3), pp.1064-1073. ⟨10.1128/IAI.01189-13⟩

International audience; Although Candida glabrata is an important pathogenic Candida species, relatively little is known about its innate immune recognition. Here, we explore the potential role of Dectin-2 for host defense against C. glabrata. Dectin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::444e14b8d9b32546e7310ad9425916bd
https://hal-pasteur.archives-ouvertes.fr/pasteur-02875466

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Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes

Publikováno v: PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2014, 10 (6), pp.e1004211. ⟨10.1371/journal.ppat.1004211⟩
PLoS Pathogens, 2014, 10 (6), pp.e1004211. ⟨10.1371/journal.ppat.1004211⟩
Plos Pathogens 6 (10), . (2014)
PLoS Pathogens, Vol 10, Iss 6, p e1004211 (2014)

The opportunistic fungal pathogen Candida glabrata is a frequent cause of candidiasis, causing infections ranging from superficial to life-threatening disseminated disease. The inherent tolerance of C. glabrata to azole drugs makes this pathogen a se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a3ccb01dc6fe4ec38b19860eda57ecc
https://publica.fraunhofer.de/handle/publica/236583

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One Small Step for a Yeast - Microevolution within Macrophages Renders Candida glabrata Hypervirulent Due to a Single Point Mutation

Autor: Oliver Bader, Martin Schaller, Ilse D. Jacobsen, Bernhard Hube, Adela Enache-Angoulvant, Daniel Fischer, Nadja Jablonowski, Sascha Brunke, Lydia Kasper, Katja Seider, Anja Wartenberg, Christophe d'Enfert

Publikováno v: PLoS Pathogens
PLoS Pathogens, 2014, 10 (10), pp.e1004478. ⟨10.1371/journal.ppat.1004478⟩
PLoS Pathogens, Public Library of Science, 2014, 10 (10), pp.e1004478. ⟨10.1371/journal.ppat.1004478.s014⟩
Plos Pathogens 10 (10), . (2014)
PLoS Pathogens, Public Library of Science, 2014, 10 (10), ⟨10.1371/journal.ppat.1004478⟩
PLoS Pathogens, 2014, 10 (10), pp.e1004478. ⟨10.1371/journal.ppat.1004478.s014⟩
PLoS Pathogens, Vol 10, Iss 10, p e1004478 (2014)

Candida glabrata is one of the most common causes of candidemia, a life-threatening, systemic fungal infection, and is surpassed in frequency only by Candida albicans. Major factors contributing to the success of this opportunistic pathogen include i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0c9d5496f487fe97c41f396b3a040f0
https://hal.inrae.fr/hal-02631278/file/brunke_2014_1.pdf

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Multiple-locus variable-number tandem-repeat analysis for rapid typing of Candida glabrata

Autor: Isabelle Biot, Emeline Didier, Anne-Sophie Ong, Jean-Mathieu Bart, Renaud Piarroux, Sandrine Roussel, Laurence Millon, Frédéric Grenouillet

Publikováno v: Journal of Clinical Microbiology
Journal of Clinical Microbiology, American Society for Microbiology, 2007, 45 (11), pp.3781-4. 〈10.1128/JCM.01603-07〉
Journal of Clinical Microbiology, American Society for Microbiology, 2007, 45 (11), pp.3781-4. ⟨10.1128/JCM.01603-07⟩

A multiple-locus variable-number tandem-repeat analysis (MLVA) using six microsatellite markers was assessed in 127 Candida glabrata isolates. Thirty-seven different genotypes, stable both in vitro and in vivo, were observed. The highest discriminato

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1802a22bafb95342ec10aa89ea613794
https://hal.archives-ouvertes.fr/hal-00341434

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New regulators of biofilm development in Candida glabrata

Autor: Christophe d'Enfert, Guilhem Janbon, Marta Riera, Estelle Mogensen

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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Research in Microbiology
Research in Microbiology, Elsevier, 2012, 163 (4), pp.297-307. ⟨10.1016/j.resmic.2012.02.005⟩
Research in Microbiology, 2012, 163 (4), pp.297-307. ⟨10.1016/j.resmic.2012.02.005⟩

Biofilm formation plays an important role in fungal pathogenesis. In this work, we used a genetic screen in order to identify and characterize genes involved in the formation of biofilms by the opportunistic fungal pathogen Candida glabrata. We ident

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d738cf741200d7013fac379be6ff006
http://hdl.handle.net/10261/249494

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Dynamic evolution of megasatellites in yeasts

Autor: Thomas Rolland, Bernard Dujon, Guy-Franck Richard

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 2010, 38 (14), pp.4731-9. ⟨10.1093/nar/gkq207⟩
Nucleic Acids Research, Oxford University Press, 2010, 38 (14), pp.4731-9. ⟨10.1093/nar/gkq207⟩

International audience; Megasatellites are a new family of long tandem repeats, recently discovered in the yeast Candida glabrata. Compared to shorter tandem repeats, such as minisatellites, megasatellite motifs range in size from 135 to more than 30

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a49ab6aa17278835bfc6f5c7a4cf16f
https://hal-pasteur.archives-ouvertes.fr/pasteur-01370686

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