Zobrazeno 1 - 4
of 4
pro vyhledávání: '"MESH: CRISPR-Associated Protein 9"'
Publikováno v:
mSphere
MSphere
MSphere, 2020, 5 (5), pp.e00620-20. ⟨10.1128/mSphere.00620-20⟩
mSphere, Vol 5, Iss 5 (2020)
MSphere
MSphere, 2020, 5 (5), pp.e00620-20. ⟨10.1128/mSphere.00620-20⟩
mSphere, Vol 5, Iss 5 (2020)
Genome editing is essential to nearly all research studies aimed at gaining insight into the molecular mechanisms underlying various biological processes, including those in the opportunistic pathogen Candida albicans. The adaptation of the CRISPR-Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6360e1acbd4ef485f7ef66fbe44ff8ca
https://doi.org/10.1128/msphere.00620-20
https://doi.org/10.1128/msphere.00620-20
Autor:
Wilhelm Vaysse-Zinkhöfer, David Viterbo, Stéphane Descorps-Declère, Lucie Poggi, Guy-Franck Richard, Valentine Mosbach
Publikováno v:
PLoS Genetics, Vol 16, Iss 7, p e1008924 (2020)
PLoS Genetics
PLoS Genetics, 2020, 16 (7), pp.e1008924. ⟨10.1371/journal.pgen.1008924⟩
PLoS Genetics
PLoS Genetics, 2020, 16 (7), pp.e1008924. ⟨10.1371/journal.pgen.1008924⟩
Microsatellites are short tandem repeats, ubiquitous in all eukaryotes and represent ~2% of the human genome. Among them, trinucleotide repeats are responsible for more than two dozen neurological and developmental disorders. Targeting microsatellite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af72aaff1c19e94d418813f2ccf2888e
https://doaj.org/article/4d98239c049246cda0811bc9d615a42e
https://doaj.org/article/4d98239c049246cda0811bc9d615a42e
Autor:
Chloé Bourguignon, John De Vos, Amel Nasri, Chloé Nguyen Van, Mathieu Fieldes, Joffrey Mianné, Said Assou
Publikováno v:
Cells
Cells, MDPI, 2020, 9 (5), pp.1312. ⟨10.3390/cells9051312⟩
Cells, Vol 9, Iss 1312, p 1312 (2020)
Cells, MDPI, 2020, 9 (5), pp.1312. ⟨10.3390/cells9051312⟩
Cells, Vol 9, Iss 1312, p 1312 (2020)
International audience; Recent advances in genome engineering based on the CRISPR/Cas9 technology have revolutionized our ability to manipulate genomic DNA. Its use in human pluripotent stem cells (hPSCs) has allowed a wide range of mutant cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e916c248fc17e1679cefe37516369cb
https://hal.umontpellier.fr/hal-03594394
https://hal.umontpellier.fr/hal-03594394
Autor:
Michael Alonge, Michael C. Schatz, Samuel F. Hutton, Zachary H. Lemmon, Fritz J. Sedlazeck, Zachary B. Lippman, José M. Jiménez-Gómez, Sebastian Soyk, Joyce Van Eck
Publikováno v:
Nature Plants
Nature Plants, Nature Publishing Group, 2019, 5 (5), pp.471-479. ⟨10.1038/s41477-019-0422-z⟩
Nature Plants, Nature Publishing Group, 2019, 5, pp.471-479. ⟨10.1038/s41477-019-0422-z⟩
Nature Plants, Nature Publishing Group, 2019, 5 (5), pp.471-479. ⟨10.1038/s41477-019-0422-z⟩
Nature Plants, Nature Publishing Group, 2019, 5, pp.471-479. ⟨10.1038/s41477-019-0422-z⟩
International audience; Genome editing technologies are being widely adopted in plant breeding1. However, a looming challenge of engineering desirable genetic variation in diverse genotypes is poor predictability of phenotypic outcomes due to unfores
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50a28bf141aeddaa7641852b0c998901
https://hal.inrae.fr/hal-03325021
https://hal.inrae.fr/hal-03325021