Výsledky vyhledávání - "MESH: Brucella suis"

Human CD4+invariant NKT cells are involved in antibacterial immunity againstBrucella suisthrough CD1d-dependent but CD4-independent mechanisms

Autor: Sherri Dudal, Stéphanie Bessoles, Virginie Lafont, Gurdyal S. Besra, Françoise Sanchez

Publikováno v: European Journal of Immunology
European Journal of Immunology, Wiley-VCH Verlag, 2009, 39 (4), pp.1025-35. ⟨10.1002/eji.200838929⟩

International audience; Human invariant NKT (iNKT) cells are a unique subset of T cells, which recognize glycolipids presented by the CD1d. Among the iNKT cells, several functionally distinct subsets have been characterized according to CD4 and/or CD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412a39fb595ad3847691ae118d42c3fc
https://doi.org/10.1002/eji.200838929

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Targeting of the Brucella suis Virulence Factor Histidinol Dehydrogenase by Histidinol Analogues Results in Inhibition of Intramacrophagic Multiplication of the Pathogen

Autor: Jean-Yves Winum, Jean-Louis Montero, Stephan Köhler, Pascale Joseph, Marie-Rose Abdo, Rose-Anne Boigegrain

Publikováno v: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2007, 51 (10), pp.3752-5. ⟨10.1128/AAC.00572-07⟩

Brucella suis histidinol dehydrogenase (HDH) can be efficiently targeted by substrate analogues. The growth of this pathogen in minimal medium was inhibited and the multiplication in human macrophages was totally abolished in the presence of the drug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::003d3e16058205b6d2de840d0c6a2ec6
https://doi.org/10.1128/aac.00572-07

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High Susceptibility of Human Dendritic Cells to Invasion by the Intracellular PathogensBrucella suis, B. abortus, andB. melitensis

Autor: Elisabeth Billard, Jacques Dornand, Chantal Cazevieille, Antoine Gross

Publikováno v: Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2005, 73 (12), pp.8418-24. ⟨10.1128/IAI.73.12.8418-8424.2005⟩

Bacteria from theBrucellagenus are able to survive and proliferate within macrophages. Because they are phylogenetically closely related to macrophages, myeloid dendritic cells (DCs) constitute potential targets forBrucellabacteria. Here we report th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf0121f3abbc3c0dc2f7eae78392c12
https://doi.org/10.1128/iai.73.12.8418-8424.2005

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Subversion and Utilization of the Host Cell Cyclic Adenosine 5′-Monophosphate/Protein Kinase A Pathway by Brucella During Macrophage Infection

Autor: Pierre Casellas, Jean-Pierre Liautard, Jacques Dornand, Monsif Bouaboula, Antoine Gross

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2003, 170 (11), pp.5607-14

Brucella spp. are intramacrophage pathogens that induce chronic infections in a wide range of mammals, including domestic animals and humans. Therefore, the macrophage response to infection has important consequences for both the survival of phagocyt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7892b29c5f1a77ffaaa8aa0731e6a7
https://doi.org/10.4049/jimmunol.170.11.5607

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The innate immune response against Brucella in humans

Autor: Jane Oliaro, Virgine Lafont, Antoine Gross, Jean-Pierre Liautard, Jacques Dornand, Janny Liautard

Publikováno v: Veterinary Microbiology
Veterinary Microbiology, Elsevier, 2002, 90 (1-4), pp.383-94. ⟨10.1016/S0378-1135(02)00223-7⟩

Pathogens have developed different strategies to survive and multiply within their host. Among them is the ability to control phagocyte apoptosis while another is to affect the expression of cytokines which is necessary for a normal protective functi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a253c52b6c9a22254462ea1b5737a2
https://doi.org/10.1016/s0378-1135(02)00223-7

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Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis

Autor: Pascale Joseph, Isao Nishimori, Claudiu T. Supuran, Andrea Scozzafava, Jean-Louis Montero, François Turtaut, Tomoko Minakuchi, Safia Ouahrani-Bettache, Jean-Yves Winum, Stephan Köhler, Daniela Vullo

Publikováno v: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2010, 53 (5), pp.2277-85. ⟨10.1021/jm901855h⟩

International audience; A beta-carbonic anhydrase (CA, EC 4.2.1.1) from the bacterial pathogen Brucella suis, bsCA 1, has been cloned, purified, and characterized kinetically. bsCA 1 has appreciable activity as catalyst for the hydration of CO(2) to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0cbe360b711fa42cd88a38af56d76d
https://pubmed.ncbi.nlm.nih.gov/20158185

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Proteomic analysis of Brucella suis under oxygen deficiency reveals flexibility in adaptive expression of various pathways

Autor: Michael Kersten, Alois Harder, Séverine Loisel-Meyer, Holger C. Scholz, Sascha Al Dahouk, Stephan Köhler, Véronique Jubier-Maurin, Herbert Tomaso, Heinrich Neubauer

Publikováno v: Proteomics
Proteomics, Wiley-VCH Verlag, 2009, 9 (11), pp.3011-21. ⟨10.1002/pmic.200800266⟩

International audience; Low oxygen tension was proposed to be one of the environmental parameters characteristic of the patho-physiological conditions of natural infections by Brucella suis. We previously showed that various respiratory pathways may

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a4109b21edeb0ea12a43aff2f0720f
https://hal.archives-ouvertes.fr/hal-00420519

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Identification and Isolation of Brucella suis Virulence Genes Involved in Resistance to the Human Innate Immune System▿

Autor: Joseph, Philippe, Abdo, M.-R., Boigegrain, R.-A., MONTERO, J.-L., Winum, J.-Y., Ouahrani-Bettache, S., Jubier-Maurin, V., Lafont, V., Köhler, S., Liautard, J.-P.

Publikováno v: Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2007, 75 (11), pp.5167-74. ⟨10.1128/IAI.00690-07⟩
Infection and Immunity, American Society for Microbiology, 2007, 75 (11), pp.5167-5174. ⟨10.1128/IAI.00690-07⟩

Brucella strains are facultative intracellular pathogens that induce chronic diseases in humans and animals. This observation implies that Brucella subverts innate and specific immune responses of the host to develop its full virulence. Deciphering t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0615df25f0da799e9a378f2f47889c5
https://europepmc.org/articles/PMC2168268/

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Brucella suis prevents human dendritic cell maturation and antigen presentation through regulation of tumor necrosis factor alpha secretion

Autor: Antoine Gross, Jacques Dornand, Elisabeth Billard

Publikováno v: Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2007, 75 (10), pp.4980-9. ⟨10.1128/IAI.00637-07⟩

Brucellais a facultative intracellular pathogen and the etiological agent of brucellosis. In some cases, human brucellosis results in a persistent infection that may reactivate years after the initial exposure. The mechanisms by which the parasite ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5691d12848c61e719394ee6887d5ef0
https://pubmed.ncbi.nlm.nih.gov/17635859

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Different roles of the two high-oxygen-affinity terminal oxidases of Brucella suis: Cytochrome c oxidase, but not ubiquinol oxidase, is required for persistence in mice

Autor: Séverine Loisel-Meyer, María Pilar Jiménez de Bagüés, Véronique Jubier-Maurin, Jean-Pierre Liautard

Publikováno v: Infection and Immunity
Infection and Immunity, American Society for Microbiology, 2007, 75 (1), pp.531-5. ⟨10.1128/IAI.01185-06⟩

The survival of Brucella suis mutant strains in mice demonstrated different roles of the two high-oxygen-affinity terminal oxidases. The cbb3 -type cytochrome c oxidase was essential for chronic infection in oxygen-deficient organs. Lack of the cytoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99238aa67971869139288f207b05c5d6
https://pubmed.ncbi.nlm.nih.gov/17101669

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