Zobrazeno 1 - 10 of 52 pro vyhledávání: '"MESH: Brain Injuries"'
1
Efficacy of Ronopterin (VAS203) in Patients with Moderate and Severe Traumatic Brain Injury (NOSTRA phase III trial): study protocol of a confirmatory, placebo-controlled, randomised, double blind, multi-centre study
Autor: Frank Tegtmeier, Reinhard Schinzel, Ronny Beer, Diederik Bulters, Jean-Yves LeFrant, Joan Sahuquillo, Andreas Unterberg, Peter Andrews, Antonio Belli, Javier Ibanez, Alfonso Lagares, Michael Mokry, Harald Willschke, Charlotte Flüh, Erich Schmutzhard, on behalf of the NOSTRA Investigators
Publikováno v: Trials
Trials, Vol 21, Iss 1, Pp 1-9 (2020)
Trials, BioMed Central, 2020, 21 (1), pp.80. ⟨10.1186/s13063-019-3965-4⟩
Background Traumatic brain injury is a leading cause of death and disability worldwide. The nitric oxide synthase inhibitor Ronopterin was shown to improve clinical outcome by enhancing neuroprotection in a phase IIa trial. Methods/design The NOSTRA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d924e29a335b9540ab3f0f935b4714dd
https://doi.org/10.1186/s13063-019-3965-4
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2
Prophylactic hydrocortisone in extremely preterm infants and brain MRI abnormality
Autor: Alison, Marianne, Tilea, Bogdana, Toumazi, Artemis, Biran, Valérie, Mohamed, Damir, Alberti, Corinne, Bourmaud, Aurélie, Baud, Olivier, PREMILOC Trial group
Publikováno v: Archives of Disease in Childhood Fetal and Neonatal Edition (2020)
Archives of disease in childhood. Fetal and neonatal edition
Archives of disease in childhood. Fetal and neonatal edition, BMJ Publishing Group, 2020, 105 (5), pp.520-525. ⟨10.1136/archdischild-2019-317720⟩
Archives of disease in childhood.Fetal and neonatal edition
Archives of disease in childhood.Fetal and neonatal edition, BMJ Publishing Group, 2020, 105 (5), pp.520-525. ⟨10.1136/archdischild-2019-317720⟩
ObjectiveTo determine whether early low-dose hydrocortisone treatment in extremely preterm infants is associated with brain damage assessed by MRI at term equivalent of age (TEA).Patients and outcomesThis is a predefined secondary analysis of brain a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5eb6be7a7c2f966726d0e3372a5ab47
https://archive-ouverte.unige.ch/unige:137352
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3
Reversible induction of TDP-43 granules in cortical neurons after traumatic injury
Autor: Lilla Tar, Luc Dupuis, Albert C. Ludolph, Akila Chandrasekar, William Tsao, Philip C. Wong, Birgit Linkus, Francesco Roselli, Florian olde Heuvel, Diana Wiesner
Publikováno v: Experimental Neurology
Experimental Neurology, 2018, 299 (Pt A), pp.15-25. ⟨10.1016/j.expneurol.2017.09.011⟩
Experimental Neurology, Elsevier, 2018, 299 (Pt A), pp.15-25. ⟨10.1016/j.expneurol.2017.09.011⟩
International audience; Traumatic brain injury (TBI) has been proposed as a risk factor for neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS). To determine whether TBI might trigger or exacerbate ALS-relevant pathology, we del
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3395d2a44b02945973656b1a11d8e3f3
https://doi.org/10.1016/j.expneurol.2017.09.011
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4
Akademický článek
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5
Akademický článek
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6
Clinical validation of S100B in the management of a mild traumatic brain injury: issues from an interventional cohort of 1449 adult patients
Autor: Vincent Sapin, Damien Bouvier, Jeannot Schmidt, Daniel Pic, Jean Roubin, Farès Moustafa, Gautier Allouchery, Bruno Pereira, Julien Raconnat
Publikováno v: Clinical Chemistry and Laboratory Medicine
Clinical Chemistry and Laboratory Medicine, De Gruyter, 2018, 56 (11), pp.1897-1904. ⟨10.1515/cclm-2018-0471⟩
Clinical Chemistry and Laboratory Medicine, 2018, 56 (11), pp.1897-1904. ⟨10.1515/cclm-2018-0471⟩
Background: This study’s primary objective was to validate the routine use of S100B via a prospective study. The aim was a reduction of cranial computed tomography (CCT) scans by 30%. The secondary goal was to investigate the influence of age and a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5cf36661140ddbd5b23f39680d98d45
https://hal.uca.fr/hal-03023653
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7
[Restoration of damaged cortical pathways by neural grafting]
Autor: Ballout, Nissrine, Péron, Sophie, Gaillard, Afsaneh
Publikováno v: médecine/sciences
médecine/sciences, EDP Sciences, 2018, 34 (8-9), pp.678-684. ⟨10.1051/medsci/20183408014⟩
International audience; The motor cortex plays a central role in the control, planning, and execution of voluntary motor commands in mammals. The loss of cortical neurons is a common feature of many neuropathological conditions such as traumatic and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a091c817e85f38fb88c8cfae687ba183
https://pubmed.ncbi.nlm.nih.gov/30230451
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8
Restauration des voies corticales lésées par greffe de neurones
Autor: Nissrine Ballout, Sophie Péron, Afsaneh Gaillard
Publikováno v: médecine/sciences
médecine/sciences, EDP Sciences, 2018, 34 (8-9), pp.678-684. ⟨10.1051/medsci/20183408014⟩
The motor cortex plays a central role in the control, planning, and execution of voluntary motor commands in mammals. The loss of cortical neurons is a common feature of many neuropathological conditions such as traumatic and ischemic lesions or seve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9aeda025583fffa933d8fe347dba064
https://hal.archives-ouvertes.fr/hal-02559299/file/msc180005.pdf
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9
Brain Damage and Motor Cortex Impairment in Chronic Obstructive Pulmonary Disease: Implication of Nonrapid Eye Movement Sleep Desaturation
Autor: Varray, Alain, Alexandre, Francois, Heraud, Nelly, Sanchez, Anthony M. J., Tremey, Emilie, Oliver, Nicolas, Gu��rin, Philippe, Sanchez, Anthony, Sanchez, Anthony M J
Publikováno v: SLEEP
SLEEP, 2016, 39 (2), pp.327-335. ⟨10.5665/sleep.5438⟩
SLEEP, American Academy of Sleep Medicine, 2016, 39 (2), pp.327-335. ⟨10.5665/sleep.5438⟩
Nonrapid eye movement (NREM) sleep desaturation may cause neuronal damage due to the withdrawal of cerebrovascular reactivity. The current study (1) assessed the prevalence of NREM sleep desaturation in nonhypoxemic patients with chronic obstructive
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2199703835be95435ea00a89c3f2fd12
https://hal.umontpellier.fr/hal-01622340
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10
Cerebral Microdialysis Effects of Propofol versus Midazolam in Severe Traumatic Brain Injury
Autor: M. Tanguy, Yannick Mallédant, Bruno Laviolle, Philippe Seguin, Jean-Paul Bleichner, Xavier Morandi
Publikováno v: Journal of Neurotrauma
Journal of Neurotrauma, 2012, 29 (6), pp.1105-10. ⟨10.1089/neu.2011.1817⟩
Journal of Neurotrauma, Mary Ann Liebert, 2012, 29 (6), pp.1105-10. ⟨10.1089/neu.2011.1817⟩
International audience; Propofol, an anesthetic agent acting as an analogue of vitamin E, has been advocated to be an ideal neuroprotective agent both in animal models and in clinical practice, due to its positive effects on oxidative stress. Neverth
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ba282406d05e1e5c37f337173358a9
https://doi.org/10.1089/neu.2011.1817
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