Zobrazeno 1 - 7 of 7 pro vyhledávání: '"MESH: Blood Coagulation Factors"'
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Modelling ligand selectivity of serine proteases using integrative proteochemometric approaches improves model performance and allows the multi-target dependent interpretation of features
Autor: Andreas Bender, Oscar Méndez-Lucio, Qurrat ul Ain, Thérèse E. Malliavin, Isidro Cortes Ciriano, Gerard J. P. van Westen
Publikováno v: Integrative Biology, 6(11), 1023-1033
Integrative biology
Integrative biology, Royal Society of Chemistry, 2014, 6 (11), pp.1023-1033. ⟨10.1039/C4IB00175C⟩
Integrative biology, 2014, 6 (11), pp.1023-1033. ⟨10.1039/C4IB00175C⟩
International audience; Serine proteases, implicated in important physiological functions, have a high intra-family similarity, which leads to unwanted off-target effects of inhibitors with insufficient selectivity. However, the availability of seque
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21869922e9275eaa5da1a64e4f0f956
https://doi.org/10.1039/c4ib00175c
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3
Increased levels of circulating microparticles are associated with increased procoagulant activity in patients with cutaneous malignant melanoma
Autor: Philippe Saas, Sabeha Biichle, Estelle Seilles, Francine Garnache-Ottou, François Aubin, Thomas Lihoreau, Fabien Pelletier, Guillaume Mourey, Philippe Humbert, C. Laresche
Publikováno v: Journal of Investigative Dermatology
Journal of Investigative Dermatology, Nature Publishing Group, 2014, 134 (1), pp.176-182. ⟨10.1038/jid.2013.288⟩
Journal of Investigative Dermatology, Nature Publishing Group, 2014, 134 (1), pp.176-182. 〈10.1038/jid.2013.288〉
International audience; Microparticles (MPs) are known to be increased in various malignancies and are involved in tumor invasion, angiogenesis, coagulation, and metastasis. We investigated the plasma levels of annexin-V MPs (AV(+)MPs), platelet-deri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853083b68b088e0d7860fff5601f67b3
https://pubmed.ncbi.nlm.nih.gov/23812302
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4
Emergency reversal of anticoagulation: the real use of prothrombin complex concentrates: a prospective multicenter two year French study from 2006 to 2008
Autor: Desmettre , Thibaut, Dubart , Alain-Eric, Capellier , Gilles, Fanara , Benoit, Puyraveau , Marc, Kepka , Sabrina, Coquart , Jeremy, Sheppard , Frances, Tazarourte , Karim
Publikováno v: Thrombosis Research
Thrombosis Research, Elsevier, 2012, 130 (3), pp.e178-83. 〈10.1016/j.thromres.2012.05.029〉
Thrombosis Research, Elsevier, 2012, 130 (3), pp.e178-83. ⟨10.1016/j.thromres.2012.05.029⟩
International audience; INTRODUCTION: Prothrombin complex concentrate (PCC) for reversal of vitamin K antagonist (VKA) is the main therapeutic option in cases of life-threatening bleeding. Clinical use of PCC is poorly documented. METHODS: We prospec
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::762d8e8f8382be1eec3334e864121281
https://hal.archives-ouvertes.fr/hal-00825707
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5
Endothelial mineralocorticoid receptor activation enhances endothelial protein C receptor and decreases vascular thrombosis in mice
Autor: Ara Parlakian, Huguette Louis, Frederic Jaisser, Aurelie Nguyen Dinh Cat, Jeremy Lagrange, Véronique Regnault, Denis Wahl, Mustapha Bourhim, Zhenlin Li, Patrick Lacolley, Céline Fassot
Publikováno v: FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2014, 28 (5), pp.2062-2072. ⟨10.1096/fj.13-238188⟩
FASEB Journal, 2014, 28 (5), pp.2062-2072. ⟨10.1096/fj.13-238188⟩
International audience; Previous studies have shown that aldosterone, which activates the mineralocorticoid receptor (MR), promotes thrombosis in animal models. Our objective was to determine whether MR activation/expression in the vascular endotheli
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641253b8bfcc130779f62ec4768760b3
https://hal.univ-lorraine.fr/hal-01738666
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6
Effect of two oral doses of 17beta-estradiol associated with dydrogesterone on thrombin generation in healthy menopausal women: a randomized double-blind placebo-controlled study
Autor: Grigoris T. Gerotziafas, Eric Dasque, Jean-Louis Démolis, Dahlia Torchin, Karine Lacut, Annie Robert, Faiez Zannad, Tabassome Simon, Alexandra Rousseau, Christian Libersa, Ismail Elalamy
Publikováno v: Fundamental and Clinical Pharmacology
Fundamental and Clinical Pharmacology, Wiley, 2010, 24 (2), pp.239-45. ⟨10.1111/j.1472-8206.2009.00747.x⟩
International audience; Oral hormone therapy is associated with an increased risk of venous thrombosis. Drug agencies recommend the use of the lowest efficient dose to treat menopausal symptoms for a better risk/ratio profile, although this profile h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3379ab5d35c48006039d395a3b1949
https://pubmed.ncbi.nlm.nih.gov/19719551
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7
Influence of coagulation factors and tissue factor concentration on the thrombin generation test in plasma
Autor: Jérôme Duchemin, Brigitte Pan-Petesch, Jean-François Abgrall, Marie-Thérèse Blouch, Bertrand Arnaud
Publikováno v: Thrombosis and Haemostasis
Thrombosis and Haemostasis, Schattauer, 2008, 99 (4), pp.767-73. ⟨10.1160/TH07-09-0581⟩
SummaryThe thrombin generation test is used to study coagulation in patients with haemorrhagic diseases or with high thrombotic risk. To our knowledge, this is the first study investigating the relative influence of coagulation factors on thrombin ge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c14e04e2dee9c34619052740b0ac429
https://hal.univ-brest.fr/hal-00685463
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