[Autologous hematopoietic cells for severe autoimmune diseases: Guidelines of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC) for immune monitoring and biobanking]

Autor: Lansiaux, Pauline, Loisel, Séverine, Castilla-Llorente, Cristina, Fontenille, Claire, Kabdani, Sarah, Marjanovic, Zora, Pugnet, Grégory, Puyade, Mathieu, Robert, Emilie, Terriou, Louis, Ait Abdallah, Nassim, Maria, Alexandre Thibault Jacques, Michel, Laure, Tréton, Xavier, Yakoub-Agha, Ibrahim, Farge, Dominique

Publikováno v: Bulletin du Cancer
Bulletin du Cancer, 2021, 108 (12), pp.S72-S81. ⟨10.1016/j.bulcan.2021.03.020⟩

International audience; Autologous hematopoietic cell transplantation (AHCT) is a new treatment option for patients with severe autoimmune diseases (AD), based on the use of intensive or myeloablative chemotherapy to eradicate the pathogenic autoreac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::37b995f5366bdce491f1c0c4bf9463f9
https://pubmed.ncbi.nlm.nih.gov/34272057

Making the Most of Clumping and Thresholding for Polygenic Scores

Autor: Michael G. B. Blum, Florian Privé, Bjarni J. Vilhjálmsson, Hugues Aschard

Publikováno v: American Journal of Human Genetics
American Journal of Human Genetics, Elsevier (Cell Press), 2019, 105 (6), pp.1213-1221. ⟨10.1016/j.ajhg.2019.11.001⟩
Am J Hum Genet
American Journal of Human Genetics, 2019, 105 (6), pp.1213-1221. ⟨10.1016/j.ajhg.2019.11.001⟩
Privé, F, Vilhjálmsson, B J, Aschard, H & Blum, M G B 2019, ' Making the Most of Clumping and Thresholding for Polygenic Scores ', American Journal of Human Genetics, vol. 105, no. 6, pp. 1213-1221 . https://doi.org/10.1016/j.ajhg.2019.11.001

Polygenic prediction has the potential to contribute to precision medicine. Clumping and Thresh-olding (C+T) is a widely used method to derive polygenic scores. When using C+T, it is common to test several p-value thresholds to maximize predictive ab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477fe48dcfd1abdc7996cb2d6df19263
https://hal.archives-ouvertes.fr/hal-02414984/file/S0002929719304227.pdf

Ethical reflections on pharmacogenetics and DNA banking in a cohort of HIV-infected patients

Autor: De Montgolfier, Sandrine, Moutel, Grégoire, Duchange, Nathalie, Hervé, Christian, Theodorou, Ioannis, Leport, Catherine

Publikováno v: Pharmacogenetics-London
Pharmacogenetics-London-, Wolters Kluwer-Lippincott Williams & Wilkins, 2002, 12 (9), pp.667-75
Pharmacogenetics-London-, 2002, 12 (9), pp.667-75

APROCO study group : collective author; The aim of this study was to analyse ethical issues concerning the storage of human biological samples to be used in genetic analyses and pharmacogenetic research based on a French experience of DNA banking in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::97cde38aba690fd6566f1fe42b29d1af
https://www.hal.inserm.fr/inserm-00000002

Study of the involvement of research ethics committees in the constitution and use of biobanks in France

Autor: Christian Hervé, Nathalie Duchange, Sandrine de Montgolfier, Catherine Beaumont, Grégoire Moutel, Lama Sharara

Publikováno v: Pharmacogenetics-London
Pharmacogenetics-London-, Wolters Kluwer-Lippincott Williams & Wilkins, 2004, 14 (3), pp.195-8

Concerns are emerging about the protection of individuals who take part in genetic research involving biobanks. We used several items of a questionnaire sent to 48 French research ethics committees (RECs) to investigate the means by which they evalua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af605be664e4534be3c893bee45486a
https://www.hal.inserm.fr/inserm-00143041