Zobrazeno 1 - 10
of 27
pro vyhledávání: '"MESH: Bile Acids and Salts"'
Autor:
Repoila, F., Le Bohec, F., Guérin, C., Lacoux, C., Tiwari, S., Jaiswal, A., Santana, M. Passos, Kennedy, Sean P., Quinquis, B., Rainteau, D., Juillard, V., Furlan, S., Bouloc, P., Nicolas, P., Miyoshi, A., Azevedo, V., Serror, P.
Publikováno v:
Scientific Reports
Scientific Reports, 2022, 12 (1), pp.8485. ⟨10.1038/s41598-022-12552-3⟩
Scientific Reports, 2022, 12 (1), pp.8485. ⟨10.1038/s41598-022-12552-3⟩
Enterococcus faecalis is a natural inhabitant of the human gastrointestinal tract. This bacterial species is subdominant in a healthy physiological state of the gut microbiota (eubiosis) in adults, but can become dominant and cause infections when th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e68d2a302f34dfdecfb4f1dc3fb3fb
https://doi.org/10.1038/s41598-022-12552-3
https://doi.org/10.1038/s41598-022-12552-3
Autor:
Eleonora Latis, David Michonneau, Sivapriya Ramamoorthy, Gérard Socié, Sylvie Chevret, Emmanuel Curis, Régis Peffault de Latour, Brian J. Ingram, Lars Rogge, Laetitia Dubouchet, Flore Sicre de Fontbrune, Marie Robin
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications
Nature Communications, 2019, 10 (1), pp.5695. ⟨10.1038/s41467-019-13498-3⟩
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.5695. ⟨10.1038/s41467-019-13498-3⟩
Nature Communications
Nature Communications, 2019, 10 (1), pp.5695. ⟨10.1038/s41467-019-13498-3⟩
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.5695. ⟨10.1038/s41467-019-13498-3⟩
Despite improvement in clinical management, allogeneic hematopoietic stem cell transplantation (HSCT) is still hampered by high morbidity and mortality rates, mainly due to graft versus host disease (GvHD). Recently, it has been demonstrated that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd2d5865d8ab2c827071aafc222f3da
http://link.springer.com/article/10.1038/s41467-019-13498-3
http://link.springer.com/article/10.1038/s41467-019-13498-3
Autor:
Bourdignon, Léa
Publikováno v:
Gynécologie et obstétrique. 2020
Background: to this day, no national guidelines on the management of intrahepatic cholestasis of pregnancy have been published even though it is the most frequent liver disease occurring during pregnancy. The major risk of this disease seems to be in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2592::c42124f448f38f48fb85c20e6a57a57d
https://dumas.ccsd.cnrs.fr/dumas-03049081
https://dumas.ccsd.cnrs.fr/dumas-03049081
Autor:
Jose Ursic-Bedoya, Isabelle Doignon, Hayat Simerabet, Dominique Rainteau, Doris Cassio, Nicolas Kahale, Anne Davit-Spraul, Thierry Tordjmann, Grégory Merlen, Lydie Humbert, Catherine Guettier, Julien Gautherot, Valeska Bidault-Jourdainne, Christoph Ullmer, Isabelle Garcin, Noémie Péan, Klaus Ebnet, Zahra Tanfin
Publikováno v:
Gut
Gut, BMJ Publishing Group, 2019, 69 (1), pp.146-157. ⟨10.1136/gutjnl-2018-316975⟩
Gut, 2019, 69 (1), pp.146-157. ⟨10.1136/gutjnl-2018-316975⟩
Gut, BMJ Publishing Group, 2019, 69 (1), pp.146-157. ⟨10.1136/gutjnl-2018-316975⟩
Gut, 2019, 69 (1), pp.146-157. ⟨10.1136/gutjnl-2018-316975⟩
ObjectiveWe explored the hypothesis that TGR5, the bile acid (BA) G-protein-coupled receptor highly expressed in biliary epithelial cells, protects the liver against BA overload through the regulation of biliary epithelium permeability.DesignExperime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660294abb0fa3eb398b53de0626d479f
https://hal.umontpellier.fr/hal-03356970
https://hal.umontpellier.fr/hal-03356970
Autor:
Céline Mulet, Laetitia Aymeric, Philippe J. Sansonetti, Claire Poyart, Marion Bérard, Shaynoor Dramsi, Azadeh Saffarian, Béatrice Regnault, Patrick Trieu-Cuot, Laurence du Merle, Françoise Donnadieu, Giulia Nigro, Sylvie Robine
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (2), pp.E283-E291. ⟨10.1073/pnas.1715112115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (2), pp.E283-E291. ⟨10.1073/pnas.1715112115⟩
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (2), pp.E283-E291. ⟨10.1073/pnas.1715112115⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2018, 115 (2), pp.E283-E291. ⟨10.1073/pnas.1715112115⟩
Significance Growing evidence indicates a correlation between colorectal cancer and intestinal dysbiosis or colonization by single bacterial species such as Streptococcus gallolyticus subsp. gallolyticus (SGG), yet a causality link remains to be esta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f4ea29949fbf387c510b1c3a038714
https://hal-pasteur.archives-ouvertes.fr/pasteur-02565479
https://hal-pasteur.archives-ouvertes.fr/pasteur-02565479
Autor:
Thierry Yandza, Jean Gugenheim, Marie-Christine Saint-Paul, Xavier Hébuterne, Veronique M. Braud, Marie F Gerhardt
Publikováno v:
Transplantation
Transplantation, Lippincott, Williams & Wilkins, 2009, 87 (1), pp.24-8. ⟨10.1097/TP.0b013e3181902b35⟩
Transplantation, Lippincott, Williams & Wilkins, 2009, 87 (1), pp.24-8. ⟨10.1097/TP.0b013e3181902b35⟩
International audience; OBJECTIVES: To examine changes in individual bile acids in serum in a pig model of allogenic small bowel transplantation. METHODS: Seventeen pigs were divided into two groups: group 1 (n=10), controls; group 2 (n=7), allotrans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::053c07a9741f08068e2d5c3899749037
https://doi.org/10.1097/tp.0b013e3181902b35
https://doi.org/10.1097/tp.0b013e3181902b35
Autor:
Alberto Massarotti, Charles Thomas, Johan Auwerx, Emiliano Rosatelli, Antonio Macchiarulo, Paola Sabbatini, Roberto Nuti, Kristina Schoonjans, Antimo Gioiello, Roberto Pellicciari
Publikováno v:
Journal of Chemical Information and Modeling
Journal of Chemical Information and Modeling, 2008, 48 (9), pp.1792-801. ⟨10.1021/ci800196h⟩
Journal of Chemical Information and Modeling, American Chemical Society, 2008, 48 (9), pp.1792-801. ⟨10.1021/ci800196h⟩
Journal of Chemical Information and Modeling, 2008, 48 (9), pp.1792-801. ⟨10.1021/ci800196h⟩
Journal of Chemical Information and Modeling, American Chemical Society, 2008, 48 (9), pp.1792-801. ⟨10.1021/ci800196h⟩
International audience; Bile acids regulate nongenomic actions through the activation of TGR5, a membrane receptor that is G protein-coupled to the induction of adenylate cyclase. In this work, a training set of 43 bile acid derivatives is used to de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c330b74dcafd574c827a05c78420141
https://doi.org/10.1021/ci800196h
https://doi.org/10.1021/ci800196h
Autor:
Johan Auwerx, Roberto Pellicciari, Gianluca Giorgi, Kristina Schoonjans, Hiroyuki Sato, Bahman M. Sadeghpour, Gabriele Costantino, Antimo Gioiello, Antonio Macchiarulo
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2007, 50 (18), pp.4265-8. ⟨10.1021/jm070633p⟩
Journal of Medicinal Chemistry, American Chemical Society, 2007, 50 (18), pp.4265-8. ⟨10.1021/jm070633p⟩
23-Alkyl-substituted and 6,23-alkyl-disubstituted derivatives of chenodeoxycholic acid are identified as potent and selective agonists of TGR5, a G-protein coupled receptor for bile acids (BAs). In particular, we show that methylation at the C-23(S)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3cfa699a9b29607cfb7429c74274dd
https://doi.org/10.1021/jm070633p
https://doi.org/10.1021/jm070633p
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2006, 25 (7), pp.1419-25. ⟨10.1038/sj.emboj.7601049⟩
EMBO Journal, EMBO Press, 2006, 25 (7), pp.1419-25. ⟨10.1038/sj.emboj.7601049⟩
International audience; Bile acids (BAs), a group of structurally diverse molecules that are primarily synthesized in the liver from cholesterol, are the chief components of bile. Besides their well-established roles in dietary lipid absorption and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c098ce6b98c7474889e07781bea7308
https://doi.org/10.1038/sj.emboj.7601049
https://doi.org/10.1038/sj.emboj.7601049
Autor:
Nadine Cerf-Bensussan, Dominique Rainteau, François Taddei, Sabine Rakotobe, Marianne De Paepe, Valérie Gaboriau-Routhiau
Publikováno v:
PLoS Genetics
PLoS Genetics, Public Library of Science, 2011, 7 (6), pp.e1002107. ⟨10.1371/journal.pgen.1002107⟩
PLoS Genetics, 2011, 7 (6), pp.e1002107. ⟨10.1371/journal.pgen.1002107⟩
PLoS Genetics, Public Library of Science, 2011, 7 (6), pp.e1002107. 〈10.1371/journal.pgen.1002107〉
PLoS Genetics, Vol 7, Iss 6, p e1002107 (2011)
Plos Genetics 6 (7), e1002107. (2011)
PLoS Genetics, Public Library of Science, 2011, 7 (6), pp.e1002107. ⟨10.1371/journal.pgen.1002107⟩
PLoS Genetics, 2011, 7 (6), pp.e1002107. ⟨10.1371/journal.pgen.1002107⟩
PLoS Genetics, Public Library of Science, 2011, 7 (6), pp.e1002107. 〈10.1371/journal.pgen.1002107〉
PLoS Genetics, Vol 7, Iss 6, p e1002107 (2011)
Plos Genetics 6 (7), e1002107. (2011)
Bacterial diversification is often observed, but underlying mechanisms are difficult to disentangle and remain generally unknown. Moreover, controlled diversification experiments in ecologically relevant environments are lacking. We studied bacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22f36bccba01192b09fd27dca77dac4
https://www.hal.inserm.fr/inserm-00709328
https://www.hal.inserm.fr/inserm-00709328