Lowering relative humidity level increases epidermal protein deimination and drives human filaggrin breakdown

Autor: Emeline Lhuillier, Hidenari Takahara, Paul R. Thompson, Guy Serre, Valérie Pendaries, Michel Simon, Marie-Claire Méchin, Laura Cau

Publikováno v: Journal of Dermatological Science
Journal of Dermatological Science, 2017, 86 (2), pp.106-113. ⟨10.1016/j.jdermsci.2017.02.280⟩
Journal of Dermatological Science, Elsevier, 2017, 86 (2), pp.106-113. ⟨10.1016/j.jdermsci.2017.02.280⟩

International audience; Background: Deimination (also known as citrullination), the conversion of arginine in a protein to citrulline, is catalyzed by a family of enzymes called peptidylarginine deiminases (PADs). Three PADs are expressed in the epid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3329a089f3a3ec98ecd7c2067a086df
https://ut3-toulouseinp.hal.science/hal-03156353