Treatment with synthetic lipophilic tyrosyl ester controls Leishmania major infection by reducing parasite load in BALB/c mice

Autor: Fatma Z. Guerfali, Hanène Attia, Youssef Gargouri, Pablo A. Leon Martinez, Ghada Mkannez, Aymen Bali, Dhafer Laouini, Imen Aissa, Rabiaa M. Sghaier

Publikováno v: Parasitology
Parasitology, Cambridge University Press (CUP), 2016, 143 (12), pp.1615-1620. ⟨10.1017/S0031182016001086⟩

SUMMARYSynthesized lipophilic tyrosyl ester derivatives with increasing lipophilicity were effective against Leishmania (L.) major and Leishmania infantum species in vitro. These findings prompted us to test in vivo leishmanicidal properties of these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75bc2abccdcddddc96eac44eca020091
https://doi.org/10.1017/s0031182016001086