Variants in SART3 cause a spliceosomopathy characterised by failure of testis development and neuronal defects

Autor: Ayers, Katie, Eggers, Stefanie, Rollo, Ben, Smith, Katherine, Davidson, Nadia, Siddall, Nicole, Zhao, Liang, Bowles, Josephine, Weiss, Karin, Zanni, Ginevra, Burglen, Lydie, Ben-Shachar, Shay, Rosensaft, Jenny, Raas-Rothschild, Annick, Jørgensen, Anne, Schittenhelm, Ralf, Huang, Cheng, Robevska, Gorjana, van den Bergen, Jocelyn, Casagranda, Franca, Cyza, Justyna, Pachernegg, Svenja, Wright, David, Bahlo, Melanie, Oshlack, Alicia, O'Brien, Terrence, Kwan, Patrick, Koopman, Peter, Hime, Gary, Girard, Nadine, Hoffmann, Chen, Shilon, Yuval, Zung, Amnon, Bertini, Enrico, Milh, Mathieu, Ben Rhouma, Bochra, Belguith, Neila, Bashamboo, Anu, Mcelreavey, Ken, Banne, Ehud, Weintrob, Naomi, Benzeev, Bruria, Sinclair, Andrew

Publikováno v: Nature Communications
Nature Communications, 2023, 14 (1), pp.3403. ⟨10.1038/s41467-023-39040-0⟩

International audience; Squamous cell carcinoma antigen recognized by T cells 3 ( SART3 ) is an RNA-binding protein with numerous biological functions including recycling small nuclear RNAs to the spliceosome. Here, we identify recessive variants in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ce46bdb7b636d4657872acece5ceafb8
https://hal.science/hal-04150348

TRF2 and Apollo Cooperate with Topoisomerase 2α to Protect Human Telomeres from Replicative Damage

Autor: Annamaria Biroccio, Eric Gilson, Anaïs Poulet, Christelle Lenain, Anna Bizard, Delphine Benarroch, Arturo Londoño-Vallejo, Erica Salvati, Laure Sabatier, Els Verhoeyen, Julia Morere, Jing Ye, Sébastien Britton, Bernard Salles, Yunlin Wu, Angela Maria Rizzo, Marc Nadal, Patrick Calsou, Adelaïde Saint-Léger, Marie Josèphe Giraud-Panis, Frédérique Magdinier, Simon Amiard, Serge Bauwens

Publikováno v: Cell
Cell, 2010, 142 (2), pp.230-242. ⟨10.1016/j.cell.2010.05.032⟩
Cell, Elsevier, 2010, 142 (2), pp.230-242. ⟨10.1016/j.cell.2010.05.032⟩
Cell, Elsevier, 2010, 142 (2), pp.230-42. ⟨10.1016/j.cell.2010.05.032⟩

International audience; Human telomeres are protected from DNA damage by a nucleoprotein complex that includes the repeat-binding factor TRF2. Here, we report that TRF2 regulates the 5' exonuclease activity of its binding partner, Apollo, a member of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b3259112ac3c7f0b1fb27e495f2a67

A new immunosensor for breast cancer cell detection using antibody-coated long alkylsilane self-assembled monolayers in a parallel plate flow chamber

Autor: Jean-Claude Ehrhart, Arnaud Brosseau, B. Bennetau, Phuong Lan Tran, Jean-Pierre Madrange, Louis Renaud, Patrick Tauc, Sylvain Allano, Laurent Thomas, Julie Morisot

Publikováno v: Biosensors and Bioelectronics
Biosensors and Bioelectronics, Elsevier, 2008, 24 (3), pp.467-74. ⟨10.1016/j.bios.2008.04.027⟩

International audience; We designed a new efficient and reliable immunosensor and demonstrated its analytic performance to capture breast cancer MCF7 and T47D cells, under laminar flow, onto antibody-coated long alkylsilane self-assembled monolayers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a642a50614fccc7b6cc4ff2328dc4442
https://doi.org/10.1016/j.bios.2008.04.027

Soluble HLA-G Molecules Are Increased during Acute Leukemia, Especially in Subtypes Affecting Monocytic and Lymphoid Lineages'

Autor: Yasmine Sebti, Renée Fauchet, Laurence Amiot, Frédéric Gros, Bernard Branger, Marc Bernard, Sophie de Guiber

Publikováno v: Neoplasia
Neoplasia, Elsevier, 2006, 8 (3), pp.223-30. ⟨10.1593/neo.05703⟩
Neoplasia, 2006, 8 (3), pp.223-30. ⟨10.1593/neo.05703⟩
Neoplasia, Elsevier, 2006, 8 (3), pp.223-230
Neoplasia: An International Journal for Oncology Research, Vol 8, Iss 3, Pp 223-230 (2006)

International audience; Human leukocyte antigen G (HLA-G) molecules exhibit immunomodulatory properties corresponding to nonclassic class I genes of the major histocompatibility complex. They are either membrane-bound or solubly expressed during cert

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948128f020947558a051cc817a209813

αvβ5/β6 integrin suppression leads to a stimulation of α2β1 dependent cell migration resistant to PI3K/Akt inhibition

Autor: Céline, Defilles, Jean-Claude, Lissitzky, Marie-Pierre, Montero, Frédéric, André, Charles, Prévot, Estelle, Delamarre, Naziha, Marrakchi, José, Luis, Véronique, Rigot

Publikováno v: Experimental Cell Research
Experimental Cell Research, Elsevier, 2009, 315 (11), pp.1840-1849. 〈10.1016/j.yexcr.2009.03.014〉
Experimental Cell Research, Elsevier, 2009, 315 (11), pp.1840-1849. ⟨10.1016/j.yexcr.2009.03.014⟩

International audience; Crosstalk between integrins is involved in the regulation of various cell functions including cell migration. Here we identify the interplay between the integrins alpha v beta 5/beta 6 and alpha 2 beta 1 during cell migration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::07d9457faf99fce16e0392ffc4d028eb
https://hal-riip.archives-ouvertes.fr/pasteur-01375182