Zobrazeno 1 - 10
of 20
pro vyhledávání: '"MESH: Antigenic Variation"'
Autor:
Faria, Joana, Glover, Lucy, Hutchinson, Sebastian, Boehm, Cordula, Field, Mark C., Horn, David
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.3023. ⟨10.1038/s41467-019-10823-8⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.3023. ⟨10.1038/s41467-019-10823-8⟩
The largest gene families in eukaryotes are subject to allelic exclusion, but mechanisms underpinning single allele selection and inheritance remain unclear. Here, we describe a protein complex sustaining variant surface glycoprotein (VSG) allelic ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::413ac617aac13601f6d8db9049163309
http://link.springer.com/article/10.1038/s41467-019-10823-8
http://link.springer.com/article/10.1038/s41467-019-10823-8
Autor:
Lucy Glover
Publikováno v:
MSphere
MSphere, American Society for Microbiology., 2020, 5 (1), ⟨10.1128/mSphere.00001-20⟩
mSphere
mSphere, Vol 5, Iss 1, p e00001-20 (2020)
MSphere, 2020, 5 (1), ⟨10.1128/mSphere.00001-20⟩
mSphere, Vol 5, Iss 1 (2020)
MSphere, American Society for Microbiology., 2020, 5 (1), ⟨10.1128/mSphere.00001-20⟩
mSphere
mSphere, Vol 5, Iss 1, p e00001-20 (2020)
MSphere, 2020, 5 (1), ⟨10.1128/mSphere.00001-20⟩
mSphere, Vol 5, Iss 1 (2020)
Lucy Glover’s research focuses on the role of DNA repair and recombination in antigenic variation in the parasite Trypanosoma brucei, the causative agent of both human and animal African trypanosomiasis. In this mSphere of Influence article, she re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5fbc5aa136cb2a51fa80e59786e39ea
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107138/document
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107138/document
Serum resistance and phase variation of a nasopharyngeal non-typeable Haemophilus influenzae isolate
Autor:
Sabine Lichtenegger, Philippe Glaser, Isabelle Bina, Sanel Durakovic, Stefan Schild, Joachim Reidl, Sarah Tutz
Publikováno v:
International Journal of Medical Microbiology
International Journal of Medical Microbiology, Elsevier, 2017, 307 (2), pp.139-146. ⟨10.1016/j.ijmm.2017.01.005⟩
International Journal of Medical Microbiology, 2017, 307 (2), pp.139-146. ⟨10.1016/j.ijmm.2017.01.005⟩
International Journal of Medical Microbiology, Elsevier, 2017, 307 (2), pp.139-146. ⟨10.1016/j.ijmm.2017.01.005⟩
International Journal of Medical Microbiology, 2017, 307 (2), pp.139-146. ⟨10.1016/j.ijmm.2017.01.005⟩
International audience; Haemophilus influenzae harbours a complex array of factors to resist human complement attack. As non-typeable H. influenzae (NTHi) strains do not possess a capsule, their serum resistance mainly depends on other mechanisms inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04abf3869ed7d75d52931af4b4969464
https://doi.org/10.1016/j.ijmm.2017.01.005
https://doi.org/10.1016/j.ijmm.2017.01.005
Autor:
Cornick, Jennifer E., Tastan Bishop, Özlem, Yalcin, Feyruz, Kiran, Anmol M., Kumwenda, Benjamin, Chaguza, Chrispin, Govindpershad, Shanil, Ousmane, Sani, Senghore, Madikay, du Plessis, Mignon, Pluschke, Gerd, Ebruke, Chinelo, McGee, Lesley, Sigaùque, Beutel, Collard, Jean-Marc, Bentley, Stephen D., Kadioglu, Aras, Antonio, Martin, von Gottberg, Anne, French, Neil, Klugman, Keith P., Heyderman, Robert S., Alderson, Mark, Everett, Dean B., PAGe consortium
Publikováno v:
Cornick, J E, Tastan Bishop, Ö, Yalcin, F, Kiran, A M, Kumwenda, B, Chaguza, C, Govindpershad, S, Ousmane, S, Senghore, M, du Plessis, M, Pluschke, G, Ebruke, C, McGee, L, Sigaùque, B, Collard, J-M, Bentley, S D, Kadioglu, A, Antonio, M, von Gottberg, A, French, N, Klugman, K P, Heyderman, R S & Alderson, M & Everett, D B 2017, ' The global distribution and diversity of protein vaccine candidate antigens in the highly virulent Streptococcus pnuemoniae serotype 1 ', Vaccine, vol. 35, no. 6, pp. 972-980 . https://doi.org/10.1016/j.vaccine.2016.12.037
Vaccine
Vaccine, Elsevier, 2017, 35 (6), pp.972-980. ⟨10.1016/j.vaccine.2016.12.037⟩
VACCINE
Vaccine
Vaccine, Elsevier, 2017, 35 (6), pp.972-980. ⟨10.1016/j.vaccine.2016.12.037⟩
VACCINE
International audience; Serotype 1 is one of the most common causes of pneumococcal disease worldwide. Pneumococcal protein vaccines are currently being developed as an alternate intervention strategy to pneumococcal conjugate vaccines. Pre-requisite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9a7dc07e15ada02b78d45905a99fd88e
https://www.pure.ed.ac.uk/ws/files/57983085/Everett_D_The_Global_distribution....pdf
https://www.pure.ed.ac.uk/ws/files/57983085/Everett_D_The_Global_distribution....pdf
Publikováno v:
Molecular and Biochemical Parasitology
Molecular and Biochemical Parasitology, 2016, 209 (1-2), pp.104-113. ⟨10.1016/j.molbiopara.2016.07.008⟩
Molecular and Biochemical Parasitology, Elsevier, 2016, 209 (1-2), pp.104-113. ⟨10.1016/j.molbiopara.2016.07.008⟩
Molecular and Biochemical Parasitology, 2016, 209 (1-2), pp.104-113. ⟨10.1016/j.molbiopara.2016.07.008⟩
Molecular and Biochemical Parasitology, Elsevier, 2016, 209 (1-2), pp.104-113. ⟨10.1016/j.molbiopara.2016.07.008⟩
International audience; The parasitic protozoa Trypanosoma brucei and Plasmodium falciparum are lethal human parasites that have developed elegant strategies of immune evasion by antigenic variation. Despite the vast evolutionary distance between the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6257f9d65c237ad430da1b1583e4bb51
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107121
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107121
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (26), pp.7225-7230. ⟨10.1073/pnas.1600344113⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2016, 113 (26), pp.7225-7230. ⟨10.1073/pnas.1600344113⟩
International audience; Allelic exclusion underpins antigenic variation and immune evasion in African trypanosomes. These bloodstream parasites use RNA polymerase-I (pol-I) to transcribe just one telomeric variant surface glycoprotein (VSG) gene at a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6b7c8bd92bc0c933e35e767d855df4ed
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107112
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107112
Autor:
Glover, Lucy, Horn, David
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2014, 42 (20), pp.12600-12613. ⟨10.1093/nar/gku900⟩
Nucleic Acids Research, Oxford University Press, 2014, 42 (20), pp.12600-12613. ⟨10.1093/nar/gku900⟩
International audience; The African trypanosome, Trypanosoma brucei, is a parasitic protozoan that achieves antigenic variation through DNA-repair processes involving Variant Surface Glycoprotein (VSG) gene rearrangements at subtelomeres. Subtelomeri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ec21e00e6b17e942085d97b365c3953a
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107111
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107111
Autor:
Bita Bordbar, Audrey Sabbagh, Sayeh Jafari-Guemouri, Dionicia Gamboa, Sedami Gnidehou, Livingstone Tavul, Didier Menard, Charlie Jennison, Philippe Deloron, Jorge Bendezu, Nicaise Tuikue Ndam, Rachida Tahar, Alyssa E. Barry, Emmanuelle Renard
Publikováno v:
Infection, Genetics and Evolution
Infection, Genetics and Evolution, Elsevier, 2014, 25, pp.81-92. ⟨10.1016/j.meegid.2014.04.010⟩
Infection, Genetics and Evolution, Elsevier, 2014, 25, pp.81-92. ⟨10.1016/j.meegid.2014.04.010⟩
International audience; In placental malaria (PM), sequestration of infected erythrocytes in the placenta is mediated by an interaction between VAR2CSA, a Plasmodium falciparum protein expressed on erythrocytes, and chondroitin sulfate A (CSA) on syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784ce02384d5c6070ba1de541962af0a
https://hal.archives-ouvertes.fr/hal-02560676
https://hal.archives-ouvertes.fr/hal-02560676
Autor:
Glover, Lucy, Hutchinson, Sebastian, Alsford, Sam, McCulloch, Richard, Field, Mark, Horn, David
Publikováno v:
Cellular Microbiology
Cellular Microbiology, Wiley, 2013, 15 (12), pp.1984-1993. ⟨10.1111/cmi.12215⟩
Cellular Microbiology, Wiley, 2013, 15 (12), pp.1984-1993. ⟨10.1111/cmi.12215⟩
International audience; African trypanosomes are lethal human and animal parasites that use antigenic variation for evasion of host adaptive immunity. To facilitate antigenic variation, trypanosomes dedicate approximately one third of their nuclear g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ec2ffed9bbab73925ef9a8c946290b80
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107113
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107113
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2013, 9 (3), pp.e1003260. ⟨10.1371/journal.ppat.1003260⟩
PLoS Pathogens, Vol 9, Iss 3, p e1003260 (2013)
PLoS Pathogens, Public Library of Science, 2013, 9 (3), pp.e1003260. ⟨10.1371/journal.ppat.1003260⟩
PLoS Pathogens, Vol 9, Iss 3, p e1003260 (2013)
Antigenic variation in African trypanosomes requires monoallelic transcription and switching of variant surface glycoprotein (VSG) genes. The transcribed VSG, always flanked by ‘70 bp’-repeats and telomeric-repeats, is either replaced through DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71340ca94e021d338c5c77aed1df63a8
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107107/file/ppat.1003260.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-03107107/file/ppat.1003260.pdf