Modelling primaquine-induced haemolysis in G6PD deficiency

Autor: James A Watson, Sim Kheng, Nicholas J. White, Didier Menard, Walter Rj Taylor

Publikováno v: eLife, Vol 6 (2017)
eLife
eLife, eLife Sciences Publication, 2017, 6, ⟨10.7554/eLife.23061⟩

Primaquine is the only drug available to prevent relapse in vivax malaria. The main adverse effect of primaquine is erythrocyte age and dose-dependent acute haemolytic anaemia in individuals with glucose-6-phosphate dehydrogenase deficiency (G6PDd).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ff22b1e5fd0ea7ddfbc8a6d8baea73b
https://elifesciences.org/articles/23061

A mutation in the Gardos channel is associated with hereditary xerocytosis

Autor: Jean-Pierre Desvignes, Hélène Guizouarn, David Salgado, Corinne Guitton, Henri Vinti, Christophe Béroud, Véronique Picard, Vanessa Nivaggioni, Marie Loosveld, Caroline Lacoste, Valérie Lacroze, Raphael Rapetti-Mauss, Patrick Viout, Madeleine Fénéant-Thibault, Catherine Badens, Isabelle Thuret, Elise Lombard, Nathalie Dasilva, Olivier Soriani, Monique Bernard

Publikováno v: Blood
Blood, American Society of Hematology, 2015, 126 (11), pp.1273-80
Blood, American Society of Hematology, 2015, 126 (11), pp.1273-1280. ⟨10.1182/blood-2015-04-642496⟩

International audience; The Gardos channel is a Ca(2+)-sensitive, intermediate conductance, potassium selective channel expressed in several tissues including erythrocytes and pancreas. In normal erythrocytes, it is involved in cell volume modificati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78049c363a77dc39b3c75091d2c232c1
https://hal.archives-ouvertes.fr/hal-01252935

Identification of rare hemoglobin variant (Hb Fairfax) causing dominant β-thalassemia phenotype in an Iranian family

Autor: Mohammad Esmaeil Akbari, Mina Izadyar, Mohammad Hamid

Publikováno v: Annals of Hematology
Annals of Hematology, Springer Verlag, 2011, 90 (3), pp.349-51. ⟨10.1007/s00277-010-1003-4⟩

Dear Editor, More than 900 hemoglobin (Hb) variants have been reported, and most variants are caused by mutations in the αor β-globin gene clusters [1]. Clinically, most of hemoglobin variants are asymptomatic, but some variants are unstable, with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6807f029fdd704f4bb8ff40f2496e895
https://hal-riip.archives-ouvertes.fr/pasteur-00750569/file/fulltext.pdf

Haemolytic anaemia and alterations in hepatic iron metabolism in aged mice lacking Cu,Zn-superoxide dismutase

Autor: Paweł Lipiński, Jarosław Woliński, Agnieszka Styś, Mikolaj A. Gralak, Jarosław Olszak, Rafał R. Starzyński, Alexandra Willemetz, François Canonne-Hergaux

Publikováno v: Biochemical Journal
Biochemical Journal, Portland Press, 2009, 420 (3), pp.383-90. ⟨10.1042/BJ20082137⟩

International audience; The continuous recycling of haem iron following phagocytosis and catabolism of senescent and damaged red blood cells by macrophages is a crucial process in the maintenance of systemic iron homoeostasis. However, little is know

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb79a8cc2e6f45b9061ea7822491de46
https://pubmed.ncbi.nlm.nih.gov/19296829

Inferring behavior from functional brain images

Autor: Denis Le Bihan, Stanislas Dehaene, Pierre-Francois Van de Moortele, Jean-Baptiste Poline, Gurvan Le Clec'H, Laurent D. Cohen

Publikováno v: Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 1998, 1 (7), pp.549-50. ⟨10.1038/2785⟩
Nature Neuroscience, 1998, 1 (7), pp.549-50. ⟨10.1038/2785⟩

Most neuroimaging experiments aim to identify brain areas whose activation correlates tightly with an aspect of the subjects' behavioral task. If the logic of neuroimaging is correct, however, it should also be possible to reverse this sequence of op

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0043cc010e9346e6faf58c86924de6ff
https://hal.archives-ouvertes.fr/hal-00349936