Effects of Subinhibitory Concentrations of Antibiotics on Colonization Factor Expression by Moxifloxacin-Susceptible and Moxifloxacin-Resistant Clostridium difficile Strains

Autor: Sylvie Bouttier, Bruno Dupuy, Cécile Denève, Claire Janoir, Anne Collignon, Frédéric Barbut

Publikováno v: Antimicrobial Agents and Chemotherapy
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, 2009, 53 (12), pp.5155-5162. ⟨10.1128/AAC.00532-09⟩
Antimicrobial Agents and Chemotherapy, 2009, 53 (12), pp.5155-5162. ⟨10.1128/AAC.00532-09⟩

Recent outbreaks of Clostridium difficile infection have been related to the emergence of the NAP1/027 epidemic strain. This strain demonstrates increased virulence and resistance to the C-8-methoxyfluoroquinolones gatifloxacin and moxifloxacin. Thes

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https://hal-pasteur.archives-ouvertes.fr/pasteur-02444048