Výsledky vyhledávání - "MESH: Amino Acid Sequence"

Single-cytosine methylation at W-boxes repels binding of WRKY transcription factors through steric hindrance

Autor: Magali Charvin, Thierry Halter, Romain Blanc-Mathieu, Pierre Barraud, Magali Aumont-Nicaise, François Parcy, Lionel Navarro

Publikováno v: Plant Physiology
Plant Physiology, 2023, 192 (1), pp.77-84. ⟨10.1093/plphys/kiad069⟩

DNA methylation is an epigenetic mark that fine-tunes gene expression, notably by negatively or positively regulating transcription factor (TF)-DNA binding. In plants, DNA methylation has primarily been shown to inhibit TF-DNA binding. However, littl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cddfafd797eae3befdcb62bba96afdc
https://hal.science/hal-04097425/document

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The coordinated replication of Vibrio cholerae’s two chromosomes required the acquisition of a unique domain by the RctB initiator

Autor: Fournes, Florian, Niault, Theophile, Czarnecki, Jakub, Tissier-Visconti, Alvise, Mazel, Didier, Val, Marie-Eve

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 2021, 49 (19), pp.11119-11133. ⟨10.1093/nar/gkab903⟩
Nucleic Acids Research, Oxford University Press, 2021, 49 (19), pp.11119-11133. ⟨10.1093/nar/gkab903⟩

International audience; Vibrio cholerae, the pathogenic bacterium that causes cholera, has two chromosomes (Chr1, Chr2) that replicate in a well-orchestrated sequence. Chr2 initiation is triggered only after the replication of the crtS site on Chr1.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::78989246a70ed6b9797197547822388d
http://europepmc.org/articles/PMC8565311

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A novel SARS-CoV-2 related coronavirus in bats from Cambodia

Autor: Deborah, Delaune, Vibol, Hul, Erik A, Karlsson, Alexandre, Hassanin, Tey Putita, Ou, Artem, Baidaliuk, Fabiana, Gámbaro, Matthieu, Prot, Vuong Tan, Tu, Sokha, Chea, Lucy, Keatts, Jonna, Mazet, Christine K, Johnson, Philippe, Buchy, Philippe, Dussart, Tracey, Goldstein, Etienne, Simon-Lorière, Veasna, Duong

Publikováno v: Nature Communications
Nature Communications, 2021, 12 (1), pp.6563. ⟨10.1038/s41467-021-26809-4⟩
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Nature communications, vol 12, iss 1

Knowledge of the origin and reservoir of the coronavirus responsible for the ongoing COVID-19 pandemic is still fragmentary. To date, the closest relatives to SARS-CoV-2 have been detected in Rhinolophus bats sampled in the Yunnan province, China. He

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3a2d8f562b07e098085a57f2fea389c5
https://hal-riip.archives-ouvertes.fr/pasteur-03576361/file/s41467-021-26809-4.pdf

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Purification and Characterization of Bot33: A Non-Toxic Peptide from the Venom of Buthus occitanus tunetanus Scorpion

Autor: Rym ElFessi, Oussema Khamessi, Najet Srairi-Abid, Jean-Marc Sabatier, Jan Tytgat, Steve Peigneur, Riadh Kharrat

Publikováno v: Molecules
Molecules, 2022, 27 (21), pp.7278. ⟨10.3390/molecules27217278⟩
Molecules; Volume 27; Issue 21; Pages: 7278

Scorpion venom is a rich source of promising therapeutic compounds, such as highly selective ion channel ligands with potent pharmacological effects. Bot33 is a new short polypeptide of 38 amino acid residues with six cysteines purified from the veno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a221efa035231934bfe4374af5d285
https://doi.org/10.3390/molecules27217278

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Orthobunyavirus spike architecture and recognition by neutralizing antibodies

Autor: Jan Hellert, Martin Beer, Ahmed Haouz, Kerstin Wernike, Félix A. Rey, Sven Reiche, Pablo Guardado-Calvo, Emiliana Brocchi, Andrea Aebischer

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.879. ⟨10.1038/s41467-019-08832-8⟩
Nature Communications, 2019, 10 (1), pp.879. ⟨10.1038/s41467-019-08832-8⟩
'Nature Communications ', vol: 10, pages: 879-1-879-14 (2019)

Orthobunyaviruses (OBVs) form a distinct genus of arthropod-borne bunyaviruses that can cause severe disease upon zoonotic transmission to humans. Antigenic drift or genome segment re-assortment have in the past resulted in new pathogenic OBVs, makin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf91ad72e3f5fade4b5c4d1a4df59311
https://doaj.org/article/2104c270a93148418cef93bdd6763c5f

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The steroid derivative 6-aminocholestanol inhibits the DEAD-box helicase eIF4A (LieIF4A) from the Trypanosomatid parasite Leishmania by perturbing the RNA and ATP binding sites

Autor: N. Kyle Tanner, Mourad Barhoumi, Emna Harigua-Souiai, Arnaud Blondel, Josette Banroques, Yosser Zina Abdelkrim, Ikram Guizani

Publikováno v: Molecular and Biochemical Parasitology
Molecular and Biochemical Parasitology, 2018, 226, pp.9-19. ⟨10.1016/j.molbiopara.2018.10.001⟩
Molecular and Biochemical Parasitology, Elsevier, 2018, 226, pp.9-19. ⟨10.1016/j.molbiopara.2018.10.001⟩

International audience; The antifungal agent 6-aminocholestanol targets the production of ergosterol, which is the principle sterol in many fungi and protozoans; ergosterol serves many of the same roles as cholesterol in animals. We found that it als

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1cab00f461442b882b9cc5b78e1a41
https://doi.org/10.1016/j.molbiopara.2018.10.001

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Analysis of diverse eukaryotes suggests the existence of an ancestral mitochondrial apparatus derived from the bacterial type II secretion system

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2947. ⟨10.1038/s41467-021-23046-7⟩
Nature Communications, 2021, 12 (1), pp.2947. ⟨10.1038/s41467-021-23046-7⟩
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

The type 2 secretion system (T2SS) is present in some Gram-negative eubacteria and used to secrete proteins across the outer membrane. Here we report that certain representative heteroloboseans, jakobids, malawimonads and hemimastigotes unexpectedly

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b800b20644833bfb7b700b78814074d6
https://hal-pasteur.archives-ouvertes.fr/pasteur-03247185

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Self-association of MreC as a regulatory signal in bacterial cell wall elongation

Autor: Carlos Contreras-Martel, Leandro F. Estrozi, Daniel M. Trindade, Mayara M. Miyachiro, Fernanda Rodrigues-Costa, Ina Attrée, Guy Schoehn, Caíque C. Malospirito, Alexandre Martins, Viviana Job, Andréa Dessen, Lionel Imbert, Manon Janet-Maitre

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), ⟨10.1038/s41467-021-22957-9⟩
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.2987. ⟨10.1038/s41467-021-22957-9⟩
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, 2021, 12 (1), pp.2987. ⟨10.1038/s41467-021-22957-9⟩

The elongasome, or Rod system, is a protein complex that controls cell wall formation in rod-shaped bacteria. MreC is a membrane-associated elongasome component that co-localizes with the cytoskeletal element MreB and regulates the activity of cell w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cfc0966af3321d6631a2a3d7bddc79
http://europepmc.org/articles/PMC8137920

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Critical assessment of protein intrinsic disorder prediction

Autor: Necci, Marco, Piovesan, Damiano, Hoque Md, Tamjidul, Walsh, Ian, Iqbal, Sumaiya, Vendruscolo, Michele, Sormanni, Pietro, Wang, Chen, Raimondi, Daniele, Sharma, Ronesh, Zhou, Yaoqi, Litfin, Thomas, Galzitskaya Oxana, Valerianovna, Lobanov Michail, Yu, Vranken, Wim, Wallner, Björn, Mirabello, Claudio, Malhis, Nawar, Dosztányi, Zsuzsanna, Erdős, Gábor, Mészáros, Bálint, Gao, Jianzhao, Wang, Kui, Hu, Gang, Wu, Zhonghua, Sharma, Alok, Hanson, Jack, Paliwal, Kuldip, Callebaut, Isabelle, Bitard-Feildel, Tristan, Orlando, Gabriele, Peng, Zhenling, Xu, Jinbo, Wang, Sheng, Jones David, T., Cozzetto, Domenico, Meng, Fanchi, Yan, Jing, Gsponer, Jörg, Cheng, Jianlin, Wu, Tianqi, Kurgan, Lukasz, Promponas Vasilis, J., Tamana, Stella, Marino-Buslje, Cristina, Martínez-Pérez, Elizabeth, Chasapi, Anastasia, Ouzounis, Christos, Dunker A., Keith, Kajava Andrey, V., Leclercq Jeremy, Y., Aykac-Fas, Burcu, Lambrughi, Matteo, Maiani, Emiliano, Papaleo, Elena, Chemes Lucia, Beatriz, Álvarez, Lucía, González-Foutel Nicolás, S., Iglesias, Valentin, Pujols, Jordi, Ventura, Salvador, Palopoli, Nicolás, Benítez Guillermo, Ignacio, Parisi, Gustavo, Bassot, Claudio, Elofsson, Arne, Govindarajan, Sudha, Lamb, John, Salvatore, Marco, Hatos, András, Monzon Alexander, Miguel, Bevilacqua, Martina, Mičetić, Ivan, Minervini, Giovanni, Paladin, Lisanna, Quaglia, Federica, Leonardi, Emanuela, Davey, Norman, Horvath, Tamas, Kovacs Orsolya, Panna, Murvai, Nikoletta, Pancsa, Rita, Schad, Eva, Szabo, Beata, Tantos, Agnes, Macedo-Ribeiro, Sandra, Manso Jose, Antonio, Pereira Pedro José, Barbosa, Davidović, Radoslav, Veljkovic, Nevena, Hajdu-Soltész, Borbála, Pajkos, Mátyás, Szaniszló, Tamás, Guharoy, Mainak, Lazar, Tamas, Macossay-Castillo, Mauricio, Tompa, Peter, Tosatto Silvio C., E., Caid, Predictors, DisProt, Curators

Publikováno v: Nature Methods
Nature Methods, 2021, 18 (5), pp.472-481. ⟨10.1038/s41592-021-01117-3⟩
Nature Methods, Nature Publishing Group, 2021, ⟨10.1038/s41592-021-01117-3⟩
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Methods, 2021, ⟨10.1038/s41592-021-01117-3⟩
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Nature Methods, Nature Publishing Group, 2021, 18 (5), pp.472-481. ⟨10.1038/s41592-021-01117-3⟩

Intrinsically disordered proteins, defying the traditional protein structure–function paradigm, are a challenge to study experimentally. Because a large part of our knowledge rests on computational predictions, it is crucial that their accuracy is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038090046479130e4d0ff797fc08550f
https://hal.sorbonne-universite.fr/hal-03329755/document

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Novel Insights into Quantitative Proteomics from an Innovative Bottom-Up Simple Light Isotope Metabolic (bSLIM) Labeling Data Processing Strategy

Autor: Jean-Michel Camadro, Samuel Terrier, Pierre Poulain, Lilian Yang-Crosson, Nicolas Sénécaut, Gelio Alves, Hendrik Weisser, Laurent Lignières, Gaëlle Lelandais, Yi-Kuo Yu

Publikováno v: Journal of Proteome Research
Journal of Proteome Research, American Chemical Society, 2021, 20 (3), pp.1476-1487. ⟨10.1021/acs.jproteome.0c00478⟩
Journal of Proteome Research, 2021, 20 (3), pp.1476-1487. ⟨10.1021/acs.jproteome.0c00478⟩
J Proteome Res

International audience; Simple light isotope metabolic labeling (SLIM labeling) is an innovative method to quantify variations in the proteome based on an original in vivo labeling strategy. Heterotrophic cells grown in U-[ 12 C] as the sole source o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb035e2f02d081958af6c42fa3a76df
https://hal.archives-ouvertes.fr/hal-03266586/file/Senecaut_2021_J_Proteome_Research.pdf

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