Výsledky vyhledávání - "MESH: Amines"

Does the environment around the H-cluster allow coordination of the pendant amine to the catalytic iron center in [FeFe] hydrogenases? Answers from theory

Autor: Carole Baffert, Ugo Cosentino, Christophe Léger, Toshiko Miyake, Vincent Fourmond, Giorgio Moro, Maurizio Bruschi, Luca De Gioia, Claudio Greco

Publikováno v: European Journal of Biochemistry
European Journal of Biochemistry, 2013, 18 (6), pp.693-700. ⟨10.1007/s00775-013-1014-4⟩
European Journal of Biochemistry, Wiley, 2013, 18 (6), pp.693-700. ⟨10.1007/s00775-013-1014-4⟩

International audience; [FeFe] hydrogenases are H2-evolving enzymes that feature a diiron cluster in their active site (the [2Fe]H cluster). One of the iron atoms has a vacant coordination site that directly interacts with H2, thus favoring its split

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c21c1156f01fe6a3313a0074aba22ce
https://doi.org/10.1007/s00775-013-1014-4

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Phosphoenolpyruvate- and ATP-dependent dihydroxyacetone kinases: covalent substrate-binding and kinetic mechanism

Autor: Philipp Schneider, Ulrich Baumann, Karin Flükiger-Brühwiler, Therese Lüthi Nyffeler, Luis F. Garcia-Alles, Christian Siebold, Hans-Beat Bürgi, Bernhard Erni

Publikováno v: Biochemistry
Biochemistry, American Chemical Society, 2004, 43 (41), pp.13037-13045. ⟨10.1021/bi048575m⟩

International audience; Dihydroxyacetone (Dha) kinases are a sequence-conserved family of enzymes, which utilize two different phosphoryldonors, ATP in animals, plants, and some bacteria, and a multiphosphoprotein of the phosphoenolpyruvate carbohydr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7f22d0d2667fdadac30454b5e31bcff
https://doi.org/10.1021/bi048575m

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Synthesis of New Alkylaminooxysterols with Potent Cell Differentiating Activities: Identification of Leads for the Treatment of Cancer and Neurodegenerative Diseases

Autor: Bruno Payré, Michael R. Paillasse, Marc Poirot, Sandrine Silvente-Poirot, Philippe de Medina

Publikováno v: Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2009, 52 (23), pp.7765-77. ⟨10.1021/jm901063e⟩
Journal of Medicinal Chemistry, 2009, 52 (23), pp.7765-77. ⟨10.1021/jm901063e⟩

International audience; We describe here the syntheses and the biological properties of new alkylaminooxysterols. Compounds were synthesized through the trans-diaxial aminolysis of 5,6-alpha-epoxysterols with various natural amines including histamin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f2003fedc2be085290f66a3a3e025e
https://doi.org/10.1021/jm901063e

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Environmentally Friendly Chemoselective Oxidation of Primary Aliphatic Amines by Using a Biomimetic Electrocatalytic System

Autor: Angèle Chiaroni, Martine Largeron, Maurice-Bernard Fleury

Publikováno v: Chemistry-A European Journal
Chemistry-A European Journal, Wiley-VCH Verlag, 2008, 14 (3), pp.996-1003. ⟨10.1002/chem.200700876⟩

International audience; Environmentally friendly oxidation of primary aliphatic amines to imines has been successfully achieved, under metal-free conditions, by the use of diverse electrogenerated o-azaquinone mediators. High catalytic performance, t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be62b6945846e09eb60a6173ed6d584
https://doi.org/10.1002/chem.200700876

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Toward a Synthetically Useful Stereoselective C−H Amination of Hydrocarbons

Autor: Philippe Dauban, Chungen Liang, Paul Muller, Robert H. Dodd, Fabien Robert-Peillard, Florence Collet

Publikováno v: Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2008, 130 (1), pp.343-50. ⟨10.1021/ja076519d⟩

International audience; Reaction between a sulfur(VI) compound and an iodine(III) oxidant in the presence of a catalytic quantity (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4232dde5a2f11c9998be98cb6c26cc8a
https://doi.org/10.1021/ja076519d

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Maternal medication use and the risk of brain tumors in the offspring: The SEARCH international case-control study

Autor: Graziella Filippini, A. H. Cardy, Raphael Peris-Bonet, Margaret R. E. McCredie, William Lijinsky, Beth A. Mueller, Julian Little, N. Won Choi, Elizabeth A. Holly, Flora Lubin, Sylvanie Cordier, Susan Preston-Martin, Annie Arslan, Roberta McKean-Cowdin

Publikováno v: International Journal of Cancer
International Journal of Cancer, Wiley, 2006, 118 (5), pp.1302-8. ⟨10.1002/ijc.21482⟩
International Journal of Cancer, 2006, 118 (5), pp.1302-8. ⟨10.1002/ijc.21482⟩

International audience; N-nitroso compounds (NOC) have been associated with carcinogenesis in a wide range of species, including humans. There is strong experimental data showing that nitrosamides (R(1)NNO.COR(2)), a type of NOC, are potent neuro-car

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d6df79acf4321fa8bc4ed7f346ccbdc
https://doi.org/10.1002/ijc.21482

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Alkylsquarates as key intermediates for the rapid preparation of original drug-inspired compounds

Autor: Lise Charruault, Benoit Deprez, Julie Charton, Rebecca Deprez-Poulain

Publikováno v: Combinatorial Chemistry and High Throughput Screening
Combinatorial Chemistry and High Throughput Screening, Bentham Science Publishers, 2008, 11 (4), pp.294-303. ⟨10.2174/138620708784246013⟩

International audience; Many natural privileged scaffolds contain a basic nitrogen atom, which often is a key element of pharmacophore and a chemically reactive centre as well. In our ongoing research program devoted to the design of targeted librari

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6840fe29a6a3836e04bec860073bd74e
https://doi.org/10.2174/138620708784246013

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Purification of Coomassie Brilliant Blue G-250 by multiple dual mode countercurrent chromatography

Autor: Mekaoui, Nazim, Chamieh, Joseph, Dugas, Vincent, Demesmay, Claire, Berthod, Alain

Publikováno v: 36th International Symposium on High-Performance Liquid Phase Separations and Related Techniques (HPLC)
36th International Symposium on High-Performance Liquid Phase Separations and Related Techniques (HPLC), Jun 2011, Budapest, Hungary. 1232, pp.134-141, 2012, ⟨10.1016/j.chroma.2011.11.022⟩

International audience; Commercial samples of Coomassie Brilliant Blue G-250 (CBB) were not pure enough to give reliable results when used as indicator of amine content in biological material. The polar and apolar impurities produce unacceptable bias

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::12f047e83f51d3193a028603330e1431
https://hal.archives-ouvertes.fr/hal-00704027

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Preferential induction of the AhR gene battery in HepaRG cells after a single or repeated exposure to heterocyclic aromatic amines

Autor: Carine Lambert, Véronique Laurent, Marie-Anne Robin, Sébastien Anthérieu, André Guillouzo, Rozenn Jossé, Pascal Loyer, Julie Dumont

Publikováno v: Toxicology and Applied Pharmacology
Toxicology and Applied Pharmacology, 2010, 249 (1), pp.91-100. ⟨10.1016/j.taap.2010.08.027⟩
Toxicology and Applied Pharmacology, Elsevier, 2010, 249 (1), pp.91-100. ⟨10.1016/j.taap.2010.08.027⟩

International audience; 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) are two of the most common heterocyclic aromatic amines (HAA) produced during cooking of meat, fish and poultry.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ade8f3e73fc634ac5e4804570630f411
https://hal.science/hal-00742145

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Alternative responses of primary tumor cells and glioblastoma cell lines to N,N-bis-(8-hydroxyquinoline-5-yl methyl)-benzyl substituted amines: Cell death versus P53-independent senescence

Autor: Sébastien Madonna, Filippo Conti, Jean-Louis Kraus, Christophe Beclin, Aurélie Tchoghandjian

Publikováno v: International Journal of Oncology
International Journal of Oncology, Spandidos Publications, 2010, 37 (6), pp.1463-70. ⟨10.3892/ijo_00000798⟩
International Journal of Oncology, 2010, 37 (6), pp.1463-70. ⟨10.3892/ijo_00000798⟩

International audience; N,N-bis-(8-hydroxyquinoline-5-yl methyl)-benzyl substituted amines (HQNBA) represent a new class of compounds showing anti-cancer activity. At the chemical level the compounds were shown to react preferentially with thiol radi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9e63d98439ca1a34ad573c6c9342a6
https://doi.org/10.3892/ijo_00000798

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