Paracrine Regulation of Aldosterone Secretion in Physiological and Pathophysiological Conditions

Autor: Antoine-Guy Lopez, Céline Duparc, Estelle Louiset, Mireille Castanet, Alexandre Naccache, Hervé Lefebvre

Publikováno v: Aldosterone
Aldosterone, 109, pp.303-339, 2019, ⟨10.1016/bs.vh.2018.10.001⟩

International audience; Aldosterone secretion by the zona glomerulosa of the adrenal cortex is controlled by circulating factors including the renin angiotensin system (RAS) and potassium. Mineralocorticoid production is also regulated through an aut

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ba513229bd9b5a71fe3e4be4a59e9a
https://hal-normandie-univ.archives-ouvertes.fr/hal-02179532

ARMC5 Mutations in a Large Cohort of Primary Macronodular Adrenal Hyperplasia: Clinical and Functional Consequences

Autor: Xavier Bertagna, Francoise Doullay, Ludivine Drougat, E. Sonnet, Jérôme Bertherat, Joël Coste, Lionel Groussin, Rossella Libé, Françoise Borson-Chazot, Stéphanie Espiard, F. Brucker-Davis, Florence Torremocha, Guillaume Assié, Felix Beuschlein, Constantine A. Stratakis, Bruno Ragazzon, Marie-Laure Raffin-Sanson, G. Barrande, Stephanie Lopez, Karine Perlemoine, Nathalie Chabbert-Buffet, Denis Pinsard, Laurence Guignat

Publikováno v: Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2015, 100 (6), pp.E926-E935. ⟨10.1210/jc.2014-4204⟩
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2015, 100 (6), pp.E926-E935. 〈10.1210/jc.2014-4204〉
Journal of Clinical Endocrinology and Metabolism, 2015, 100 (6), pp.E926-E935. ⟨10.1210/jc.2014-4204⟩

International audience; CONTEXT:Primary bilateral macronodular adrenal hyperplasia (PBMAH) is a rare cause of primary adrenal Cushing's syndrome (CS). ARMC5 germline mutations have been identified recently in PBMAH.OBJECTIVE:To determine the prevalen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b58015651154f33524026374fe950e0
https://hal.univ-lorraine.fr/hal-01813998

The obesity-associated transcription factor ETV5 modulates circulating glucocorticoids

Autor: Abigail M.K. Thompson, Randy J. Seeley, Yvan de Launoit, Yvonne M. Ulrich-Lai, Nathalie Marchand, Ruth Gutierrez-Aguilar, Stephen C. Woods, Patrick Dumont

Publikováno v: Physiology and Behavior
Physiology and Behavior, Elsevier, 2015, 150, pp.38-42. ⟨10.1016/j.physbeh.2015.03.027⟩
Physiology and Behavior, Elsevier, 2016, 150, pp.38-42. ⟨10.1016/j.physbeh.2015.03.027⟩

International audience; The transcription factor E-twenty-six version 5 (ETV5) has been linked with obesity in genome-wide association studies. Moreover, ETV5-deficient mice (knockout; KO) have reduced body weight, lower fat mass, and are resistant t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd33ad3421f7eb576f6c6c107b48ecc9
https://hal.archives-ouvertes.fr/hal-03059809

Aldosterone-producing adenoma formation in the adrenal cortex involves expression of stem/progenitor cell markers

Autor: Enzo Lalli, Mathilde Sibony, Xavier Jeunemaitre, Sheerazed Boulkroun, José-Felipe Golib-Dzib, Arndt Benecke, Pierre-François Plouin, Tchao Meatchi, Benoit Samson-Couterie, Maria-Christina Zennaro, Laurence Amar, Estelle Louiset, Hervé Lefebvre

Publikováno v: Endocrinology
Endocrinology, Endocrine Society, 2011, 152 (12), pp.4753-63. ⟨10.1210/en.2011-1205⟩
Endocrinology, Endocrine Society, 2011, 152 (12), pp.4753-63. 〈10.1210/en.2011-1205〉
Endocrinology, 2011, 152 (12), pp.4753-63. ⟨10.1210/en.2011-1205⟩

International audience; Aldosterone producing adenoma (APA) is the most common form of surgically curable hypertension. To further understand mechanisms involved in APA formation, we investigated the expression of molecules linked to adrenal stem/pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ba5a081e2dbf7ae23919fe8731606a
https://hal.archives-ouvertes.fr/hal-00728048

Intraadrenal Corticotropin in Bilateral Macronodular Adrenal Hyperplasia

Autor: Isabelle Boutelet, Jean-Marc Kuhn, Céline Duparc, Antoine Tabarin, Lionel Groussin, Xavier Bertagna, Jacques Young, Rossella Libé, Fabienne Grunenberger, Hervé Lefebvre, Sylvie Renouf, Youssef Anouar, Jérôme Bertherat, Philippe Caron, Milène Tetsi Nomigni, Sophie Christin-Maitre, Estelle Louiset, Zakariae Bram

Publikováno v: New England Journal of Medicine
New England Journal of Medicine, Massachusetts Medical Society, 2013, 369 (22), pp.2115-2125. ⟨10.1056/NEJMoa1215245⟩

BACKGROUND Bilateral macronodular adrenal hyperplasia is a rare cause of primary adrenal Cushing’s syndrome. In this form of hyperplasia, hypersecretion of cortisol suppresses the release of corticotropin by pituitary corticotrophs, which results i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86800cac3c306a6ed4b736236a5f565c
https://hal-normandie-univ.archives-ouvertes.fr/hal-01908272