Výsledky vyhledávání - "MESH: 4-Aminopyridine"

Preparation of 3,4-diaminopyridine microparticles by solvent-evaporation methods

Autor: Aurélie Bonneville, Alain Astier, Stéphane Gibaud

Publikováno v: International Journal of Pharmaceutics
International Journal of Pharmaceutics, Elsevier, 2002, 242 (1-2), pp.197-201

International audience; The present study compares two methods of preparation of microparticles of 3,4-diaminopyridine (3,4-DAP) for the treatment for multiple sclerosis and Lambert-Eaton myasthenia syndrome. Poly( epsilon -caprolactone) microparticl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26473449f17c7933bbbbafeb40dd4080
https://doi.org/10.1016/s0378-5173(02)00157-6

Zobrazit plný text záznamu

Layer-specific generation and propagation of seizures in slices of developing neocortex: role of excitatory GABAergic synapses

Autor: Yuri Zilberter, Yehezkel Ben-Ari, Sylvain Rheims, Alfonso Represa

Publikováno v: Journal of Neurophysiology
Journal of Neurophysiology, American Physiological Society, 2008, 100 (2), pp.620-8. ⟨10.1152/jn.90403.2008⟩

The neonatal period is critical for seizure susceptibility, and neocortical networks are central in infantile epilepsies. We report that application of 4-aminopyridine (4-AP) to immature (P6–P9) neocortical slices generates layer-specific intericta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc1beeeeb49be78659a74f34bbc24f9
https://pubmed.ncbi.nlm.nih.gov/18497363

Zobrazit plný text záznamu

The anchoring protein SAP97 retains Kv1.5 channels in the plasma membrane of cardiac myocytes

Autor: Joëlle Abi-Char, Roger Vranckx, Stéphane N. Hatem, Alain Coulombe, Elise Balse, Nathalie Neyroud, Said El-Haou

Publikováno v: AJP-Heart and Circulatory Physiology
AJP-Heart and Circulatory Physiology, American Physiological Society, 2008, 294 (4), pp.H1851-H1861. ⟨10.1152/ajpheart.01045.2007⟩
AJP-Heart and Circulatory Physiology, 2008, 294 (4), pp.H1851-H1861. ⟨10.1152/ajpheart.01045.2007⟩

Membrane- associated guanylate kinase proteins (MAGUKs) are important determinants of localization and organization of ion channels into specific plasma membrane domains. However, their exact role in channel function and cardiac excitability is not k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4800e94b07608e89040e07c24bc9371
https://pubmed.ncbi.nlm.nih.gov/18245566

Zobrazit plný text záznamu

Neuromuscular paralysis and recovery in mice injected with botulinum neurotoxins A and C

Autor: Morbiato , Laura, Carli , Luca, Johnson , Eric A, Montecucco , Cesare, Molgó , Jordi, Rossetto , Ornella

Publikováno v: European Journal of Neuroscience
European Journal of Neuroscience, Wiley, 2007, 25 (9), pp.2697-704. 〈10.1111/j.1460-9568.2007.05529.x〉

Botulinum neurotoxin type A (BoNT/A) is commonly used in human therapy. This treatment may induce immunoresistance and preliminary evaluation of other botulinum neurotoxin serotypes suggested botulinum neurotoxin type C (BoNT/C) to be a good alternat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::e73a95837893074744c7439155105b2d
https://hal.archives-ouvertes.fr/hal-00163881

Zobrazit plný text záznamu

Generation and propagation of 4-AP-induced epileptiform activity in neonatal intact limbic structures in vitro

Autor: Luhmann, Heiko, Dzhala, V. I., Ben-Ari, yehezkel

Publikováno v: European Journal of Neuroscience
European Journal of Neuroscience, Wiley, 2000, 12 (8), pp.2757-68

International audience; We examined the generation, propagation and pharmacology of 4-aminopyridine (4-AP)-induced epileptiform activity (EA) in the intact interconnected limbic structure of the newborn (P0-7) rat in vitro. Whole-cell recordings of C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2997960d00aeb62d22357063615c2fa5
https://www.hal.inserm.fr/inserm-00484942/document

Zobrazit plný text záznamu

Cellular and synaptic effect of substance P on neonatal phrenic motoneurons

Autor: Ptak, K., Konrad, M., Di Pasquale, E., Tell, F., Hilaire, G., Monteau, R.

Publikováno v: European Journal of Neuroscience
European Journal of Neuroscience, Wiley, 2000, 12 (1), pp.126-38
European Journal of Neuroscience, 2000, 12 (1), pp.126-38

Experiments were carried out on the in vitro brainstem-spinal cord preparation of the newborn rat to analyse the effects of substance P (SP) on phrenic motoneuron (PMN) activity. In current-clamp mode, SP significantly depolarized PMNs, increased the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::be2748d4fbb1be31e8bbea23c88ac47a
https://hal.archives-ouvertes.fr/hal-00290947

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání