Výsledky vyhledávání - "MESH: 3T3-L1 Cells"

Identification of adipocytes as target cells for Leishmania infantum parasites

Autor: Schwing, Aurélie, Pisani, Didier, Pomares, Christelle, Majoor, Alissa, Lacas-Gervais, Sandra, Jager, Jennifer, Lemichez, Emmanuel, Marty, Pierre, Boyer, Laurent, Michel, Grégory

Publikováno v: Scientific Reports
Scientific Reports, 2021, 11 (1), pp.21275. ⟨10.1038/s41598-021-00443-y⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)

International audience; Leishmania infantum is the causative agent of visceral leishmaniasis transmitted by the bite of female sand flies. According to the WHO, the estimated annual incidence of leishmaniasis is one million new cases, resulting in 30

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d40324873466a431fa9416398403f539
https://hal-pasteur.archives-ouvertes.fr/pasteur-03744940

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Gene Expression Pattern in Response to Cholecalciferol Supplementation Highlights Cubilin as a Major Protein of 25(OH)D Uptake in Adipocytes and Male Mice White Adipose Tissue

Autor: Catherine Defoort, Esma Karkeni, Lauriane Bonnet, Jean-François Landrier, Jean-Charles Martin, Charlène Couturier, Julie Dalifard, Franck Tourniaire, Ljubica Svilar, Julien Astier

Publikováno v: Endocrinology
Endocrinology, 2018, 159 (2), pp.957-966. ⟨10.1210/en.2017-00650⟩
Endocrinology, Endocrine Society, 2018, 159 (2), pp.957-966. ⟨10.1210/en.2017-00650⟩

International audience; It is well established that the active form of vitamin D (i.e., 1,25-dihydroxyvitamin D [1,25(OH)2D]) regulates the expression of genes involved in its own metabolism and transport in the kidney and possibly in the liver. Howe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b72d54a4233ab33c63bda0d37451eb
https://amu.hal.science/hal-01998528

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Peroxisome Proliferator-activated Receptor γ Regulates Genes Involved in Insulin/Insulin-like Growth Factor Signaling and Lipid Metabolism during Adipogenesis through Functionally Distinct Enhancer Classes

Autor: Stéphane Avner, Philippe Froguel, Bart Staels, Gilles Salbert, Philippe Lefebvre, Frédérik Oger, Jérôme Eeckhoute, Julie Dubois-Chevalier, Emmanuelle Durand, Céline Gheeraert

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2014, 289 (2), pp.708-22. ⟨10.1074/jbc.M113.526996⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2014, 289 (2), pp.708-22. ⟨10.1074/jbc.M113.526996⟩

International audience; The nuclear receptor peroxisome proliferator-activated receptor (PPAR) is a transcription factor whose expression is induced during adipogenesis and that is required for the acquisition and control of mature adipocyte function

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f7349ef1c6a85a4c44d1d8089118bb
https://doi.org/10.1074/jbc.m113.526996

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DNA damage and the activation of the p53 pathway mediate alterations in metabolic and secretory functions of adipocytes Running title: DNA damage and p53 in obese adipocytes

Autor: Vergoni, Bastien, Cornejo, Pierre-Jean, Gilleron, Jérôme, Dedjani, Mansour, Ceppo, Franck, Jacquel, Arnaud, Bouget, Gwennaelle, Ginet, Clémence, Gonzalez, Teresa, Maillet, Julie, Dhennin, Véronique, Verbanck, Marie, Auberger, Patrick, Froguel, Philippe, Tanti, Jean-François, Cormont, Mireille

Publikováno v: Diabetes
Diabetes, American Diabetes Association, 2016, 65 (10), pp.3062-3074. ⟨10.2337/db16-0014⟩
Diabetes, 2016, 65 (10), pp.3062-3074. ⟨10.2337/db16-0014⟩

International audience; Activation of the p53 pathway in adipose tissue contributes to insulin resistance associated with obesity. However, the mechanisms of p53 activation and the impact on adipocyte functions are still elusive. Here we found a high

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9c8b20bbd82ba41801276eb174839a70
https://www.hal.inserm.fr/inserm-01345698

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A Possible Inflammatory Role of Twist1 in Human White Adipocytes

Autor: Amanda T. Pettersson, Anne Bouloumié, Mikael Rydén, Peter Arner, Ingrid Dahlman, Niklas Mejhert, Jurga Laurencikiene, Erik Näslund

Publikováno v: Diabetes
Diabetes, 2010, 59 (3), pp.564-71. ⟨10.2337/db09-0997⟩
Diabetes; Vol 59

OBJECTIVE Twist1 is a transcription factor that is highly expressed in murine brown and white adipose tissue (WAT) and negatively regulates fatty acid oxidation in mice. The role of twist1 in WAT is not known and was therefore examined. RESEARCH DESI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c8e894b627cc2b28b37f069f72832e6
https://doi.org/10.2337/db09-0997

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Interleukin-1β-Induced Insulin Resistance in Adipocytes through Down-Regulation of Insulin Receptor Substrate-1 Expression

Autor: Mireille Cormont, T Grémeaux, Jennifer Jager, Yannick Le Marchand-Brustel, Jean-François Tanti

Publikováno v: Endocrinology
Endocrinology, Endocrine Society, 2007, 148 (1), pp.241-51. ⟨10.1210/en.2006-0692⟩

Inflammation is associated with obesity and insulin resistance. Proinflammatory cytokines produced by adipose tissue in obesity could alter insulin signaling and action. Recent studies have shown a relationship between IL-1beta level and metabolic sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::502a891031b530affe16248045bf5864
https://doi.org/10.1210/en.2006-0692

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Cdk4 promotes adipogenesis through PPARγ activation

Autor: Pierre Dubus, Françoise Vignon, Dominique Langin, Lluis Fajas, Anna Abella, Mariano Barbacid, Sushil G. Rane, Marcos Malumbres, Audrey Sicard, Hiroaki Kiyokawa

Publikováno v: Cell Metabolism
Cell Metabolism, Elsevier, 2005, 2 (4), pp.239-49. ⟨10.1016/j.cmet.2005.09.003⟩
Cell Metabolism, 2005, 2 (4), pp.239-49. ⟨10.1016/j.cmet.2005.09.003⟩

SummaryCell cycle regulators such as E2F1 and retinoblastoma (RB) play crucial roles in the control of adipogenesis, mostly by controlling the transition between preadipocyte proliferation and adipocyte differentiation. The serine-threonine kinase cy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a5e271bcce38539433de1f53c2761fb
https://doi.org/10.1016/j.cmet.2005.09.003

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Deciphering the role of GLUT4 N-glycosylation in adipocyte and muscle cell models

Autor: Roland Govers, Nancy Zaarour, Yannick Le Marchand-Brustel, Marion Berenguer

Publikováno v: Biochemical Journal
Biochemical Journal, Portland Press, 2012, 445 (2), pp.265-73
Biochemical Journal, Portland Press, 2012, 445 (2), pp.265-73. ⟨10.1042/BJ20120232⟩
Biochemical Journal, 2012, 445 (2), pp.265-73. ⟨10.1042/BJ20120232⟩

International audience; GLUT4 (glucose transporter 4) is responsible for the insulin-induced uptake of glucose by muscle and fat cells. In non-stimulated (basal) cells, GLUT4 is retained intracellularly, whereas insulin stimulation leads to its trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f424f683b4d9a6d4fd66f88cbd7df428
https://hal.archives-ouvertes.fr/hal-01478346

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The Paired Basic Amino Acid-cleaving Enzyme 4 (PACE4) Is Involved in the Maturation of Insulin Receptor Isoform B: an opportunity to reduce the specific insulin receptor-dependent effects of insulin-like growth factor 2 (IGF2)

Autor: Kara, Imène, Poggi, Marjorie, Bonardo, Bernadette, Govers, Roland, Landrier, Jean-François, Tian, Sun, Leibiger, Ingo, Day, Robert, Creemers, John W. M., Peiretti, Franck

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, 2015, 290 (5), pp.2812-2821. ⟨10.1074/jbc.M114.592543⟩

International audience; Background: The insulin receptor exists as two isoforms: IRA and IRB. Results: IRA and IRB are similarly matured by furin, but when furin activity is reduced, IRB is matured by PACE4. Conclusion: Proprotein convertase inhibiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1398::f991c11e4fa5ffb934c37c81d66d4c32
https://www.hal.inserm.fr/inserm-01478251/document

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The Paired Basic Amino Acid-cleaving Enzyme 4 (PACE4) Is Involved in the Maturation of Insulin Receptor Isoform B

Autor: Kara, Imène, Poggi, Marjorie, Bonardo, Bernadette, Govers, Roland, Landrier, Jean-François, Tian, Sun, Leibiger, Ingo, Day, Robert, Creemers, John W. M., Peiretti, Franck

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2015, 290 (5), pp.2812-2821. ⟨10.1074/jbc.M114.592543⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2015, 290 (5), pp.2812-21
Journal of Biological Chemistry, 2015, 290 (5), pp.2812-2821. ⟨10.1074/jbc.M114.592543⟩
Journal of Biological Chemistry 5 (290), 2812-2821. (2015)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::50345e3890c70786af6585f3945180b4
https://www.hal.inserm.fr/inserm-01478251/document

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