Zobrazeno 1 - 10
of 20 411
pro vyhledávání: '"MESENCHYMAL STROMAL CELLS"'
Autor:
Yoann Athiel, Laura Cariot, Jean-Marie Jouannic, Corentin Maillet, Vincent Mauffré, Clovis Adam, Hélène Huet, Jérôme Larghero, Justine Nasone, Lucie Guilbaud
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Background The aim of this study was to assess the safety and efficacy of human umbilical cord mesenchymal stromal cells (hUC-MSCs) patch used as an adjuvant therapy in fetal myelomeningocele (MMC) surgery in the ovine model. Methods hUC-MSC
Externí odkaz:
https://doaj.org/article/12155f64f8fb4eef85111e1a86cbee4c
Autor:
Darja Marolt Presen, Vanessa Goeschl, Dominik Hanetseder, Laura Ogrin, Alexandra-Larissa Stetco, Anja Tansek, Laura Pozenel, Bella Bruszel, Goran Mitulovic, Johannes Oesterreicher, Johannes Zipperle, Barbara Schaedl, Wolfgang Holnthoner, Johannes Grillari, Heinz Redl
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Background Human induced pluripotent stem cells represent a scalable source of youthful tissue progenitors and secretomes for regenerative therapies. The aim of our study was to investigate the potential of conditioned medium (CM) from hiPSC
Externí odkaz:
https://doaj.org/article/5f30f58b46244a1a9d29c678452bb930
Autor:
Yesuf Siraj, Domenico Aprile, Nicola Alessio, Gianfranco Peluso, Giovanni Di Bernardo, Umberto Galderisi
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Senescent cells exert their effects through the release of various factors, collectively referred to as the senescence-associated secretory phenotype (SASP). The SASP can induce senescence in healthy cells (secondary senescence), modulate im
Externí odkaz:
https://doaj.org/article/7ca2260704324ce08536535e572d8132
Autor:
Erming Zhao, Rukang Liang, Panlong Li, Di Lu, Shuhan Chen, Weikeng Tan, Yunfei Qin, Yana Zhang, Yingcai Zhang, Qi Zhang, Qiuli Liu
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background Acetaminophen (APAP) overdose is a significant cause of drug-induced liver injury (DILI). N-acetylcysteine (NAC) is the first-line agent used in the clinic. However, it rarely benefits patients with advanced APAP toxicity. Mesench
Externí odkaz:
https://doaj.org/article/63264ab744aa4625b9270d79eff08888
Autor:
A. V. Smirnov, V. I. Sychev, S. M. Kuznetsova, V. A. Kalsin, V. S. Vasilyev, Yu. V. Ivanov, V. R. Stankevich, D. V. Sazonov, F. G. Zabozlaev, M. A. Konoplyannikov, V. P. Baklaushev, A. V. Troitsky
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract Background Standard approaches to the treatment of chronic post-radiation proctitis are associated with a high risk of complications and a high percentage of unsatisfactory results due to the reduced regenerative potential of irradiated tiss
Externí odkaz:
https://doaj.org/article/711c493d71ac486c8bc1c8498ea5815f
Publikováno v:
Stem Cells and Cloning: Advances and Applications, Vol Volume 17, Pp 33-39 (2024)
Haifa A Al Turki,1 Shaheed S Al-Suhaibani,2 Danah Y AlShamlan,1 Ayesha Ahmed,3 Hussain A Alhawaj4 1Department of Obstetrics and Gynecology, Imam AbdulRahman Bin Faisal University, Dammam and King Fahd Hospital of the University, AlKhobar, Saudi Arabi
Externí odkaz:
https://doaj.org/article/bac449a7c661460da11abee0eae104eb
PTGER4 signaling regulates class IIa HDAC function and SPINK4 mRNA levels in rectal epithelial cells
Autor:
Murugadas Anbazhagan, Garima Sharma, Shanta Murthy, Sushma Chowdary Maddipatla, Vasantha L. Kolachala, Anne Dodd, Amanda Randunne, David J. Cutler, Subra Kugathasan, Jason D. Matthews
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background The prostaglandin receptor PTGER4 facilitates homeostasis in the gut. Previous reports indicate that goblet cells, marked by SPINK4 expression, might be affected by PTGER4 activity. Current evidence suggests that prostaglandin E2
Externí odkaz:
https://doaj.org/article/703b6ce950e24a41929fb944510436e4
Autor:
Megumi Yokomizo-Goto, Nana Takenaka-Ninagawa, Chengzhu Zhao, Clémence Kiho Bourgeois Yoshioka, Mayuho Miki, Souta Motoike, Yoshiko Inada, Denise Zujur, William Theoputra, Yonghui Jin, Junya Toguchida, Makoto Ikeya, Hidetoshi Sakurai
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Background Ullrich congenital muscular dystrophy (UCMD) is caused by a deficiency in type 6 collagen (COL6) due to mutations in COL6A1, COL6A2, or COL6A3. COL6 deficiency alters the extracellular matrix structure and biomechanical properties
Externí odkaz:
https://doaj.org/article/f340ceaf0581411496358769fb395f06
Autor:
Nour Ebrahim, Nikolay Kondratyev, Alexander Artyuhov, Alexei Timofeev, Nadya Gurskaya, Alexey Andrianov, Roman Izrailov, Egor Volchkov, Tatyana Dyuzheva, Elena Kopantseva, Ekaterina Kiseleva, Vera Golimbet, Erdem Dashinimaev
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background Mesenchymal stromal cells (MSCs) are recognized for their potential in regenerative medicine, attributed to their multipotent differentiation capabilities and immunomodulatory properties. Despite this potential, the classification
Externí odkaz:
https://doaj.org/article/8599933f3e78417799be8b84324609da
Autor:
Alexandra N. Borelli, Courtney L. Schultze, Mark W. Young, Bruce E. Kirkpatrick, Kristi S. Anseth
Publikováno v:
Bioactive Materials, Vol 44, Iss , Pp 152-163 (2025)
Cell interactions with the extracellular matrix (ECM) influence intracellular signaling pathways related to proliferation, differentiation, and secretion, amongst other functions. Herein, bone-marrow derived mesenchymal stromal cells (MSCs) are encap
Externí odkaz:
https://doaj.org/article/1d80636ca0c44339aec8153252d56e49