Zobrazeno 1 - 10
of 57
pro vyhledávání: '"MENGYA ZHONG"'
Autor:
Jinshui Tan, Mengya Zhong, Yanyan Hu, Guangchao Pan, Jingwei Yao, Yuanfang Tang, Hongpeng Duan, Yuelong Jiang, Weihang Shan, Jiaqi Lin, Yating Liu, Jiewen Huang, Huijian Zheng, Yong Zhou, Guo Fu, Zhifeng Li, Bing Xu, Jie Zha
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Refractory or relapsed (R/R) AML is the most challenging form of AML to treat. Due to frequent genetic mutations, therapy alternatives are limited. Here, we identified the role of ritanserin and its target DGKα in AML. Several AML cell line
Externí odkaz:
https://doaj.org/article/ed795b3fcb3644ed9cb15069fa02179c
Autor:
Haijun Zhao, Yuelong Jiang, Fusheng Lin, Mengya Zhong, Jinshui Tan, Yong Zhou, Long Liu, Guowei Li, Manman Deng, Bing Xu
Publikováno v:
Experimental Hematology & Oncology, Vol 11, Iss 1, Pp 1-14 (2022)
Abstract Background Leukemia stem cells (LSCs) are responsible for the initiation and perpetuation of acute myeloid leukemia (AML), and also represent leukemia relapse reservoirs with limited therapeutic approaches. Thus, additional treatment strateg
Externí odkaz:
https://doaj.org/article/8041ed2f41ae4be8952ae24cc4b778f9
Autor:
Qinwei Chen, Suqi Deng, Manman Deng, Yuanfei Shi, Mengya Zhong, Lihong Ding, Yuelong Jiang, Yong Zhou, Bing Z. Carter, Bing Xu
Publikováno v:
Experimental Hematology & Oncology, Vol 11, Iss 1, Pp 1-4 (2022)
Abstract Dysregulation of MDM2, a p53 negative regulator, frequently occurs in acute myeloid leukemia (AML) and is associated with unfavorable prognoses, rendering the p53-MDM2 axis an attractive target for the development of small-molecule inhibitor
Externí odkaz:
https://doaj.org/article/c1fbba5b8da04b61859915b7ecb0f9dd
Autor:
Nengneng Li, Shiquan Xu, Shuaishuai Zhang, Qiang Zhu, Xiaole Meng, Wenbin An, Baoqing Fu, Mengya Zhong, Yan Yang, Zeyang Lin, Xueni Liu, Junjie Xia, Jie Wang, Tingting You, Changxiu Yan, Huamei Tang, Guohong Zhuang, Zhihai Peng
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
BackgroundThe etiology and pathogenesis of inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), are generally believed to be related to immune dysfunction and intestinal microbiota disorder. However, the exa
Externí odkaz:
https://doaj.org/article/1ff619ce14ff43479efe5c5886839dea
Autor:
Zhengxin Wu, Jinshui Tan, Yifan Zhuang, Mengya Zhong, Yubo Xiong, Jingsong Ma, Yan Yang, Zhi Gao, Jiabao Zhao, Zhijian Ye, Huiwen Zhou, Yuekun Zhu, Haijie Lu, Xuehui Hong
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-13 (2021)
Abstract Background Metabolic reprogramming has been reported in various kinds of cancers and is related to clinical prognosis, but the prognostic role of pyrimidine metabolism in gastric cancer (GC) remains unclear. Methods Here, we employed DEG ana
Externí odkaz:
https://doaj.org/article/7f2bf3d552e143838ed1267ad59a64e8
Autor:
Mingtao Ao, Fei Yu, Yixiang Li, Mengya Zhong, Yonghe Tang, Hua Yang, Xiaojing Wu, Yifan Zhuang, Huiyun Wang, Xiaolian Sun, Xuehui Hong, Xiao Dong Chen
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Abstract Background Nanoscale drug delivery systems have emerged as broadly applicable approach for chemo-photothermal therapy. However, these nanoscale drug delivery systems suffer from carrier-induced toxicity, uncontrolled drug release and low dru
Externí odkaz:
https://doaj.org/article/f75d20e259724a9d8f70de26bd8742cc
Autor:
Yubo Xiong, Yifan Zhuang, Mengya Zhong, Wenjuan Qin, Boyi Huang, Jiabao Zhao, Zhi Gao, Jingsong Ma, Zhengxin Wu, Xuehui Hong, Zhicao Yue, Haijie Lu
Publikováno v:
Cancer Control, Vol 29 (2022)
Introduction The PER2 (Period circadian regulator 2) gene is related to the circadian clock, and it has been deemed as a suppressor gene in osteosarcoma and lung carcinoma. However, the part of PER2 in CRC (colorectal cancer) needs to be further dete
Externí odkaz:
https://doaj.org/article/3a78465b911c4961a228f0ba28a15d82
Autor:
Mengya Zhong, Jinshui Tan, Guangchao Pan, Yuelong Jiang, Hui Zhou, Qian Lai, Qinwei Chen, Liyuan Fan, Manman Deng, Bing Xu, Jie Zha
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
The key factors leading to transformed follicular lymphoma (t-FL) include the aberrations of epigenetic modifiers as early and driving events, especially mutations in the gene encoding for histone acetyltransferase. Therefore, reversal of this phenom
Externí odkaz:
https://doaj.org/article/3d713885de444a33b83a276132d8180e
Autor:
Yuanfang Tang, Mengya Zhong, Guangchao Pan, Jinshui Tan, Chendi Xie, Yuelong Jiang, Jingwei Yao, Weihang Shan, Jiaqi Lin, Jiewen Huang, Yating Liu, Zhifeng Li, Bing Xu, Jie Zha
Publikováno v:
Pharmaceuticals, Vol 16, Iss 1, p 15 (2022)
Transformed follicular lymphoma (t-FL), for which there is no efficient treatment strategy, has a rapid progression, treatment resistance, and poor prognosis, which are the main reasons for FL treatment failure. In this study, we identified a promisi
Externí odkaz:
https://doaj.org/article/40f2f2cd18014b5ab8bc4a9c0019fd00
Autor:
Yunhan Ma, Baiyi Xie, Junjun Guo, Yingyu Chen, Mengya Zhong, Qingru Lin, Jianyu Hua, Jiaying Zhong, Xuewei Luo, Guoliang Yan, Helong Dai, Zhongquan Qi
Publikováno v:
Cell Transplantation, Vol 30 (2021)
Xenotransplantation is a potential solution for the severe shortage of human donor organs and tissues. The generation of humanized animal models attenuates strong innate immune responses, such as complement-mediated hyperacute rejection. However, acu
Externí odkaz:
https://doaj.org/article/0b8064bd5a1c498f85293c37590d46d2