Zobrazeno 1 - 10
of 722
pro vyhledávání: '"MENG Pan"'
Autor:
Qingya Liu, Yun Yang, Meng Pan, Kun Shi, Dong Mo, Yicong Li, Meng Wang, Linfeng Guo, Zhiyong Qian
Publikováno v:
Bioactive Materials, Vol 41, Iss , Pp 413-426 (2024)
Camptothecin (CPT) exhibits potent antitumor activity; however, its clinical application is limited by significant gastrointestinal adverse effects (GAEs). Although the severity of GAEs associated with CPT derivatives has decreased, the incidence rat
Externí odkaz:
https://doaj.org/article/781146cb3c244788a055150516694bb6
Autor:
Tingyu Yang, Liqun Dai, Jie Liu, Yi Lu, Meng Pan, Lili Pan, Lin Ye, Liping Yuan, Xicheng Li, Zhongwu Bei, Zhiyong Qian
Publikováno v:
Bioactive Materials, Vol 44, Iss , Pp 447-460 (2025)
Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, characterised by a short survival period, high malignancy, strong invasiveness, and high rates of recurrence and metastasis. Due to its unique molecular phenotype,
Externí odkaz:
https://doaj.org/article/73b0b7f8f9d44b40816b0aecf44255e4
Autor:
Afiba Manza-A Agovi, Caitlin T. Thompson, Kevin J. Craten, Esther Fasanmi, Meng Pan, Rohit P. Ojha, Erika L. Thompson
Publikováno v:
Implementation Science Communications, Vol 5, Iss 1, Pp 1-11 (2024)
Abstract Background Long-acting injectable cabotegravir plus rilpivirine (LAI CAB/RPV) has several potential benefits over daily oral formulations for HIV treatment, including the potential to facilitate long-term adherence and reduce pill fatigue. W
Externí odkaz:
https://doaj.org/article/00cf97ea2cd54d16bfcb2508621911db
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionMRTX1133 is a selective and reversible small molecule inhibitor of KRAS (G12D), which significantly delays the progression of solid tumors. However, no study on the absorption, distribution, and excretion of MRTX1133.MethodsA fast ultra-h
Externí odkaz:
https://doaj.org/article/e5a6cd78a1f2477b9c22217978656cfd
Autor:
Yun Yang, Qingya Liu, Meng Wang, Lang Li, Yan Yu, Meng Pan, Danrong Hu, Bingyang Chu, Ying Qu, Zhiyong Qian
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract Cell membrane-camouflaged nanoparticles possess inherent advantages derived from their membrane structure and surface antigens, including prolonged circulation in the bloodstream, specific cell recognition and targeting capabilities, and pot
Externí odkaz:
https://doaj.org/article/246d337172cb4032a02d1c258ca1c5e6
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundMyasthenia Gravis (MG) is an autoimmune disease that causes muscle weakness in 80% of patients, most of whom test positive for anti-acetylcholine receptor (AChR) antibodies (AChR-Abs). Predicting and improving treatment outcomes are necessa
Externí odkaz:
https://doaj.org/article/453db45df3254b6c966d3a5c2e5c1ae6
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract The treatment of colorectal cancer is always a major challenge in the field of cancer research. The number of estimated new cases of colorectal cancer worldwide in 2020 is 1 148 515, and the estimated number of deaths is 576 858, revealing t
Externí odkaz:
https://doaj.org/article/b88f0ebe3d5a4e789a3f2052a872c4f4
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 9, p 321 (2024)
Hepatic fibrosis is a major public health problem that endangers human wellbeing. In recent years, a number of studies have revealed the important impact of metabolic reprogramming on the occurrence and development of hepatic fibrosis. Among them, th
Externí odkaz:
https://doaj.org/article/ee0e4973d9994a1a9d58c863d2f5d500
Publikováno v:
Materials Today Bio, Vol 25, Iss , Pp 100980- (2024)
Pulmonary fibrosis (PF) is a serious and progressive fibrotic interstitial lung disease that is possibly life-threatening and that is characterized by fibroblast accumulation and collagen deposition. Nintedanib and pirfenidone are currently the only
Externí odkaz:
https://doaj.org/article/aabaaec7ae8749d09c1a220c2624e099
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 7, Pp 2926-2954 (2023)
Sonodynamic therapy (SDT) is an emerging noninvasive treatment modality that utilizes low-frequency and low-intensity ultrasound (US) to trigger sensitizers to kill tumor cells with reactive oxygen species (ROS). Although SDT has attracted much atten
Externí odkaz:
https://doaj.org/article/fb3b1c95cb5145e5aae09b28c46d0ac2