Zobrazeno 1 - 10
of 38
pro vyhledávání: '"MEM, minimum essential medium"'
Autor:
Teruki Nii, Yasuhiko Tabata
Publikováno v:
Regenerative Therapy, Vol 18, Iss, Pp 516-522 (2021)
Regenerative Therapy
Regenerative Therapy
Introduction The objective of this study is to design a co-culture system of cancer cells and three-dimensional (3D) mesenchymal stem cells (MSC) aggregates for the in vitro evaluation of cancer invasion. Methods First, the MSC of an immunosuppressiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30478d0d874b865560a7aa85190b7a7e
http://hdl.handle.net/2433/277951
http://hdl.handle.net/2433/277951
Autor:
Shinichiro Ono, Kyoichiro Maekawa, Kengo Kanetaka, Mampei Yamashita, Tamotsu Kuroki, Masaaki Hidaka, Toshiyuki Adachi, Naomi Matsumura, Susumu Eguchi, Tomohiko Adachi, Yusuke Sakai
Publikováno v:
Regenerative Therapy, Vol 16, Iss, Pp 42-52 (2021)
Regenerative Therapy
Regenerative Therapy
Introduction Intraportal islet transplantation is a promising therapeutic approach for patients with type 1 diabetes mellitus (T1DM). However, despite being minimally invasive, the method has some limitations, such as short-term graft loss, portal ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::893c069593595c8b4c866ee01a5eb3c2
http://www.sciencedirect.com/science/article/pii/S2352320420301012
http://www.sciencedirect.com/science/article/pii/S2352320420301012
Autor:
Fatemeh Namazi, Seifollah Dehghani Nazhvani, Iman Haghani, Abbas Ghaderi, Fatemeh Dehghani Nazhvani
Publikováno v:
Annals of Medicine and Surgery
Background Liver cirrhosis is a chronic disease in which normal liver tissue is replaced by fibrous tissue, leads to liver malfunction. Although transplantation is the most certain cure, stem cell therapies are shedding light on efforts to regenerate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e51e3c9f52533e5f37abaa05301d5f
http://europepmc.org/articles/PMC7593263
http://europepmc.org/articles/PMC7593263
Autor:
Dushyantha Jayaweera, Aisha Khan, Xian Ming Chu, Huilan Wang, Michael A. Bellio, Andrea da Fonseca Ferreira, Chunming Dong, Lukun Zhang, Qianhuan Zhang, Joshua M. Hare, Jianqing Wei, Liyong Wang
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • EVs derived from young, but not aged, MSCs rejuvenate senescent EPCs in vitro, recapitulating the effect of MSC transplantation. • Aged MSCs can be genetically modified to produce tailored EVs with increased EPC
Highlights • EVs derived from young, but not aged, MSCs rejuvenate senescent EPCs in vitro, recapitulating the effect of MSC transplantation. • Aged MSCs can be genetically modified to produce tailored EVs with increased EPC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2afc19ee994840a31f2daf0844a791
http://europepmc.org/articles/PMC7691285
http://europepmc.org/articles/PMC7691285
Autor:
Ping Zhang, Dingyuan Ma, Li-Ying Peng, Ning-Yuan Sun, Jun Chen, Xiao-Wei Zhang, Weiwei Tang, Lin An
Publikováno v:
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1397-1413 (2020)
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1397-1413 (2020)
Pyroptosis is a form of programmed cell death, and recently described as a new molecular mechanism of chemotherapy drugs in the treatment of tumors. Miltirone, a derivative of phenanthrene-quinone isolated from the root of Salvia miltiorrhiza Bunge,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750fb5bad337ad6389f2c3000e4927a2
http://europepmc.org/articles/PMC7488361
http://europepmc.org/articles/PMC7488361
Publikováno v:
Regenerative Therapy
Regenerative Therapy, Vol 14, Iss, Pp 196-204 (2020)
Regenerative Therapy, Vol 14, Iss, Pp 196-204 (2020)
Introduction The objective of this study is to design a cancer invasion model where the cancer invasion rate can be regulated in vitro. Methods Cancer-associated fibroblasts (CAF) aggregates incorporating gelatin hydrogel microspheres (GM) containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c948a87e79509c3976bbda11d75b658e
http://europepmc.org/articles/PMC7058408
http://europepmc.org/articles/PMC7058408
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 686-695 (2020)
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 686-695 (2020)
Graphical abstract
Hepatocellular carcinoma (HCC) is an essentially incurable inflammation-related cancer. We have previously shown by network analysis of proteomic data that the flavonoids epigallocatechin gallate (EGCG) and fisetin (FIS) effic
Hepatocellular carcinoma (HCC) is an essentially incurable inflammation-related cancer. We have previously shown by network analysis of proteomic data that the flavonoids epigallocatechin gallate (EGCG) and fisetin (FIS) effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc2b7c496c6b1b9ca88af07fd67f672e
https://doi.org/10.1016/j.csbj.2020.03.006
https://doi.org/10.1016/j.csbj.2020.03.006
Autor:
Salvatore Santamaria, Josefin Ahnström, Kazuhiro Yamamoto, Daniel R. Martin, Xiangyi Dong, Suneel S. Apte
Publikováno v:
JOURNAL OF BIOLOGICAL CHEMISTRY
The Journal of Biological Chemistry
The Journal of Biological Chemistry
A disintegrin-like and metalloprotease domain with thrombospondin type 1 motifs (ADAMTS)8 is a secreted protease, which was recently implicated in pathogenesis of pulmonary arterial hypertension (PAH). However, the substrate repertoire of ADAMTS8 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3115da798faea6b0b44fa4b59c972eb
Autor:
Skyler Kuhn, Michael M Gottesman, Frances Maher, Da Yin, Robert W. Robey, Jordan M. Hotz, Sachi Horibata, Ruchi P. Patel
Publikováno v:
Translational Oncology
Translational Oncology, Vol 14, Iss 1, Pp 100917-(2021)
Translational Oncology, Vol 14, Iss 1, Pp 100917-(2021)
Highlights • Subpopulations of cisplatin-resistant cells are cross-resistant to anti-microtubule drugs. • Resistance mechanisms in cisplatin-resistant ovarian cancer cells are diverse. • Increased TNF and NFκB signaling found in cisplatin-resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636ba93dc8cc9508c9c866f6ce289f2c
http://europepmc.org/articles/PMC7586247
http://europepmc.org/articles/PMC7586247
Publikováno v:
Redox Biology, Vol 28, Iss, Pp-(2020)
Redox Biology
Redox Biology
Secondary bile acids promote gastrointestinal (GI) tract permeabilization both in vivo and in vitro. Consumption of high fat diets increases bile acid levels in the GI tract which can contribute to intestinal permeabilization and consequent local and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4af562de8ff014cc32a110b05441027
https://ueaeprints.uea.ac.uk/id/eprint/72745/
https://ueaeprints.uea.ac.uk/id/eprint/72745/