Zobrazeno 1 - 10
of 539
pro vyhledávání: '"MEK/ERK pathway"'
Autor:
Haiping Liu, Limin Wang
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Objective To explore the mechanism of action of MicroRNAs-34a (miR-34a) and Eurite growth guiding factor 1 (Netrin1) in cisplatin resistance in gastric cancer (GC), providing new clues for overcoming tumor resistance and optimizing anti-tumo
Externí odkaz:
https://doaj.org/article/42ecb4f15d1c43a7b02eb07d4d9402c7
Autor:
Yosuke Tabei, Yoshihiro Nakajima
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Epithelial–mesenchymal transition (EMT) is a cellular process in embryonic development, wound healing, organ fibrosis, and cancer metastasis. Previously, we and others have reported that proinflammatory cytokine interleukin-1β (IL-1β) in
Externí odkaz:
https://doaj.org/article/d20b3ab2fe964bcfb34ff7e812d986e3
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-17 (2024)
Abstract Background Osteosarcoma is a diverse and aggressive bone tumor. Driver genes regulating osteosarcoma initiation and progression remains incompletely defined. Zinc finger protein 692 (ZNF692), a kind of Krüppel C2H2 zinc finger transcription
Externí odkaz:
https://doaj.org/article/bfae2eb996c44fd89a2ab5ba11b4f4b2
Autor:
Liangming Zhang, Xiongfeng Chen, Jianwei Wang, Meihong Chen, Juan Chen, Wanzhen Zhuang, Yu Xia, Zhixin Huang, Yue Zheng, Yi Huang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Cysteine protease inhibitor 1 (CST1) is a cystatin superfamily protein that inhibits cysteine protease activity and is reported to be involved in the development of many malignancies. Mitochondrial oxidative phosphorylation (OXPHOS) also pla
Externí odkaz:
https://doaj.org/article/77e5bc931213410190d160d2d1321dab
Publikováno v:
Heliyon, Vol 10, Iss 8, Pp e29556- (2024)
Objective: Long-term alcohol consumption can cause organic damage to the brain, resulting in mental and nervous system abnormalities and intellectual impairment. Huanglian Jiedu decoction (HLJDD) is the classic representative of clearing heat and det
Externí odkaz:
https://doaj.org/article/8a8006adac2f42e3809fa4805de9f604
Autor:
Hantae Jo, Eun-Young Lee, Hyun Sang Cho, Md Abu Rayhan, Ahyoung Cho, Chang-Suk Chae, Hye Jin You
Publikováno v:
Medicina, Vol 60, Iss 6, p 1009 (2024)
Background and Objectives: As modulators of the tumor microenvironment, macrophages have been extensively studied for their potential in developing anticancer strategies, particularly in regulating macrophage polarization towards an antitumorigenic (
Externí odkaz:
https://doaj.org/article/460bb30e82d8485ca3acbda42eefd60b
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
Though DNMTs inhibitors were widely used in myelodysplastic syndrome and leukaemia, their application in solid tumours has been limited by low response rate and lack of optimal combination strategies. In gastric cancer (GC), the therapeutic implicati
Externí odkaz:
https://doaj.org/article/cf65dc01fb1246bf9492b518d01e632f
Publikováno v:
Regenerative Therapy, Vol 21, Iss , Pp 216-224 (2022)
Introduction: Chronic obstructive pulmonary disease (COPD) is a leading cause of high mortality and heavy burden in the world. Unfortunately, emphysema, as an important component of COPD, has no curative treatments currently. Recently, human umbilica
Externí odkaz:
https://doaj.org/article/5875634f8b834e9e982d7ebe7e42216f
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Akademický článek
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