Zobrazeno 1 - 8
of 8
pro vyhledávání: '"MEI-SHENG LAU"'
Autor:
Mei Sheng Lau, Zhenhua Hu, Xiaodan Zhao, Yaw Sing Tan, Jinyue Liu, Hua Huang, Clarisse Jingyi Yeo, Hwei Fen Leong, Oleg V. Grinchuk, Justin Kaixuan Chan, Jie Yan, Wee-Wei Tee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Regulation of global transcription output is important for normal development and disease, but little is known about the mechanisms involved. DNA topoisomerase I (TOP1) is an enzyme well-known for its role in relieving DNA supercoils for ena
Externí odkaz:
https://doaj.org/article/07b9f7d58a174f738ea42b0c54df09f6
SummaryPolycomb group (PcG) proteins maintain the repressed state of lineage-inappropriate genes and are therefore essential for embryonic development and adult tissue homeostasis. One critical function of PcG complexes is modulating chromatin struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e4bd4dfa9d5de8ba1f36ee96644e3ca
https://doi.org/10.1101/2022.08.25.505322
https://doi.org/10.1101/2022.08.25.505322
Autor:
Benjamin Jieming Chen, Esther Sook Miin Wong, Haihan Tan, Wee-Wei Tee, Hwei Fen Leong, Zhenhua Hu, Dennis E.K. Tan, Baojiang Wu, Mei Sheng Lau, Ying Swan Ho, Siqin Bao, Gloryn Chia, Xuezhi Bi, Dongxiao Yang, Kelly Tan
Publikováno v:
Nature Cell Biology. 22:175-186
Mouse embryonic stem cells (ESCs) sporadically transit into an early embryonic-like state characterized by the expression of 2-cell (2C) stage-restricted transcripts. Here, we identify a maternal factor-negative elongation factor A (NELFA)-whose hete
Autor:
Clifford J. Tabin, Sharmistha Kundu, Sharon K. Marr, Ruslan I. Sadreyev, Peggy I. Wang, Andrej J. Savol, Matthew G. Schwartz, Daniel J. Grau, Patrick Schorderet, Robert E. Kingston, Mei Sheng Lau
Publikováno v:
Science. 355:1081-1084
Polycomb group gene silencing Histone proteins wrap around DNA to form nucleosomes that package metazoan DNA into the nucleus. Chromatin compaction is also believed to be critical for the repression of homeotic genes by the Polycomb repressive comple
Autor:
Zhenhua, Hu, Dennis Eng Kiat, Tan, Gloryn, Chia, Haihan, Tan, Hwei Fen, Leong, Benjamin Jieming, Chen, Mei Sheng, Lau, Kelly Yu Sing, Tan, Xuezhi, Bi, Dongxiao, Yang, Ying Swan, Ho, Baojiang, Wu, Siqin, Bao, Esther Sook Miin, Wong, Wee-Wei, Tee
Publikováno v:
Nature cell biology. 22(2)
Mouse embryonic stem cells (ESCs) sporadically transit into an early embryonic-like state characterized by the expression of 2-cell (2C) stage-restricted transcripts. Here, we identify a maternal factor-negative elongation factor A (NELFA)-whose hete
Publikováno v:
Gene Therapy & Regulation (World Scientific Publishing Company). Dec2009, Vol. 4 Issue 1, p81-104. 24p. 2 Diagrams, 2 Charts.
Autor:
Boon Seng Soh, Mikael Huss, Na-Yu Chia, Huck-Hui Ng, Jianming Jiang, Pin Li, Frederic Bard, Thomas Lufkin, Xinyi Lu, Yun-Shen Chan, Pankaj Kumar, Lin Yang, Neil D. Clarke, Bo Feng, Bing Lim, Mei-Sheng Lau, Petra Kraus, Dimitri Moreau, Yuriy L. Orlov
Publikováno v:
Nature. 468(7321)
The derivation of human ES cells (hESCs) from human blastocysts represents one of the milestones in stem cell biology. The full potential of hESCs in research and clinical applications requires a detailed understanding of the genetic network that gov
Autor:
Na-Yu Chia, Yun-Shen Chan, Bo Feng, Xinyi Lu, Orlov, Yuriy L., Moreau, Dimitri, Kumar, Pankaj, Lin Yang, Jianming Jiang, Mei-Sheng Lau, Huss, Mikael, Boon-Seng Soh, Kraus, Petra, Li, Pin, Lufkin, Thomas, Lim, Bing, Clarke, Neil D., Bard, Frederic, Ng, Huck-Hui
Publikováno v:
Nature; 11/11/2010, Vol. 468 Issue 7321, p316-320, 5p, 1 Diagram, 3 Graphs