Zobrazeno 1 - 10
of 1 851
pro vyhledávání: '"MEGALIN"'
Autor:
Anna Durinova, Lucie Smutna, Pavel Barta, Rajamanikkam Kamaraj, Tomas Smutny, Bernhard Schmierer, Petr Pavek, Frantisek Trejtnar
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-16 (2024)
Abstract Background Megalin (LRP2 receptor) mediates the endocytosis of radiolabeled peptides into proximal tubular kidney cells, which may cause nephrotoxicity due to the accumulation of a radioactive tracer. The study aimed to develop a cellular mo
Externí odkaz:
https://doaj.org/article/597d143506c24767ad940c67ab4c86df
Autor:
Akour, A.1 a.akour@ju.edu.jo, Kasabri, V.1, Bulatova, N.1, Al-Motassem, Y.1, Fahmawi, H.1, Momani, M.1, Zayed, A.1, Alquoqa, R.1, AlHawari, H.1
Publikováno v:
Bratislava Medical Journal / Bratislavské Lekárske Listy. Jul2019, Vol. 120 Issue 7, p532-535. 4p.
Akademický článek
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Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36679- (2024)
Background: miRNA has been implicated in regulating cholesterol homeostasis, a critical factor in gallstone formation. Here, we focused on elucidating the role of miR-146a in this pathological process. Methods: C57BL/6 mice were fed with lithogenic d
Externí odkaz:
https://doaj.org/article/49c9408e1ec64e989bf8b314205f0700
Publikováno v:
陆军军医大学学报, Vol 46, Iss 5, Pp 434-441 (2024)
Objective To observe the distribution of membrane transporters, Megalin and Cubilin, in the renal development of mice, and to reveal the temporal and spatial rules of their functional differentiation during renal development. Methods C57BL/6 mice wer
Externí odkaz:
https://doaj.org/article/f11dc63eb76a43b7815d742f27a17c77
Publikováno v:
FEBS Open Bio, Vol 14, Iss 2, Pp 322-330 (2024)
Tubular activation and deposition of filtered complement proteins have been implicated in the progression of proteinuric kidney disease. The potent C3b‐specific nanobody inhibitor of the alternative pathway, EWE‐hC3Nb1, is likely freely filtered
Externí odkaz:
https://doaj.org/article/1ee955e7bd1f47098aedcfb79eb5d01d
Autor:
Sudharshan Jagennath, Vadivelan Mehalingam, Prashant S Adole, Gandhipuram Periyasamy Senthilkumar
Publikováno v:
Journal of Family Medicine and Primary Care, Vol 13, Iss 2, Pp 635-639 (2024)
Purpose: Megalin is a glycoprotein molecule found on proximal renal tubular epithelial cells. The objectives of this study were to determine urinary megalin levels in non-diabetic subjects and in patients with and without type 2 diabetic nephropathy
Externí odkaz:
https://doaj.org/article/f5a59ecab5394c93ac1d068b2e801d0d
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Proximal tubule (PT) cells maintain a high-capacity apical endocytic pathway to recover essentially all proteins that escape the glomerular filtration barrier. The multi ligand receptors megalin and cubilin play pivotal roles in the endocytic uptake
Externí odkaz:
https://doaj.org/article/6b94c10a7dd042539ac83512d59ec578
Autor:
Jensen, Danny1,2 doktordanny@gmail.com, Kierulf-Lassen, Casper3, Kristensen, Marie Louise Vindvad3, Nørregaard, Rikke3, Weyer, Kathrin1, Nielsen, Rikke1, Christensen, Erik Ilsø1, Birn, Henrik1,2
Publikováno v:
PLoS ONE. 6/2/2017, Vol. 12 Issue 6, p1-13. 13p.
Autor:
Bartolome, Fernando1,2, Antequera, Desiree1,2, Tavares, Eva3, Pascual, Consuelo1,2, Maldonado, Rosario3, Camins, Antoni2,4, Carro, Eva1,2 carroeva@h12o.es
Publikováno v:
Journal of Neuroinflammation. 1/31/2017, Vol. 14, p1-10. 10p.