Zobrazeno 1 - 10
of 330
pro vyhledávání: '"MEF2A"'
Autor:
Yufen Chen, Zhen Wang, Xiaolu Qu, Bangmin Song, Yueting Tang, Bugao Li, Guoqing Cao, Guoqiang Yi
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
BackgroundPorcine skeletal muscle development is pivotal for improving meat production. TP63, a transcription factor, regulates vital cellular processes, yet its role in skeletal muscle proliferation is unclear.MethodsThe effects of TP63 on skeletal
Externí odkaz:
https://doaj.org/article/7e52151642c14c0da6afda43ebc8232f
Autor:
Zhao Wang, Menghan Luo, Qian Liang, Ke Zhao, Yuelin Hu, Wei Wang, Xiangling Feng, Bolang Hu, Jianjin Teng, Tianyi You, Ran Li, Zhengkai Bao, Wenhao Pan, Tielong Yang, Chao Zhang, Ting Li, Xiaobao Dong, Xianfu Yi, Ben Liu, Li Zhao, Miaoxin Li, Kexin Chen, Weihong Song, Jilong Yang, Mulin Jun Li
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-32 (2023)
Abstract Background The high mutation rate throughout the entire melanoma genome presents a major challenge in stratifying true driver events from the background mutations. Numerous recurrent non-coding alterations, such as those in enhancers, can sh
Externí odkaz:
https://doaj.org/article/ea2c5d7f313e4e34877e64882a16ffd9
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-13 (2023)
Abstract Background This study aimed to investigate the role of histone deacetylase 5 (HDAC5) in ventricular remodeling and explore the therapeutic potential of the HDAC5 inhibitor LMK235. Methods A transverse aortic constriction (TAC) mouse model an
Externí odkaz:
https://doaj.org/article/cf1e580085694ba49c8ea65b3edf1939
Autor:
Alfan Kurniawan, Muhammad Halim Natsir, Suyadi Suyadi, Osfar Sjofjan, Yuli Frita Nuningtyas, Ari Ardiantoro, Ahmad Furqon, Suci Puji Lestari
Publikováno v:
Journal of Genetic Engineering and Biotechnology, Vol 21, Iss 1, Pp 1-9 (2023)
Abstract Background Myogenic enhancer transcription factor 2A (MEF2A) is a transcription factor known for its role in controlling skeletal muscle regeneration and metabolic processes, while activating transcription factor 3 (ATF3) is a stress-induced
Externí odkaz:
https://doaj.org/article/7b59d24a1da548fcbb5140949351eba7
Akademický článek
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Publikováno v:
Anatolian Journal of Cardiology, Vol 26, Iss 5, Pp 373-381 (2022)
Background: Myocardial infarction, a coronary heart disease, is a serious hazard to human health. Cardiomyocyte oxidative stress and apoptosis have been considered as the main causes of myocardial infarction. Here, we aimed to investigate the role of
Externí odkaz:
https://doaj.org/article/b17a16b1958242e0839dc6f731125e0e
Autor:
Xinmiao Wang, Rui Li, Luping Wu, Yang Chen, Shaopeng Liu, Hui Zhao, Yifan Wang, Lin Wang, Zhe Shao
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Background Epigenetic reprogramming is involved in multiple steps of human cancer evolution and is mediated by a variety of chromatin-modifying enzymes. Specifically, the histone lysine methyltransferase KMT2D is among the most frequently mu
Externí odkaz:
https://doaj.org/article/443d4463a66f46c5b0edb93b6f209a9a
Autor:
Yankang Cui, Chenkui Miao, Shouyong Liu, Jingyuan Tang, Jing Zhang, Hengtao Bu, Yuhao Wang, Chao Liang, Meiling Bao, Chao Hou, Jiajin Wu, Xiaochao Chen, Xiang Zhang, Zengjun Wang, Bianjiang Liu
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 26, Iss , Pp 1336-1350 (2021)
Seminoma is the most common subtype of testicular germ cell tumor, with an increasing incidence worldwide. Clusterin (CLU) expression was found to be downregulated in testicular seminoma in our previous study. We now expanded the sample size, and fur
Externí odkaz:
https://doaj.org/article/5892ed501ea840abbc07b33ffcaf8bb9
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 12, p 324 (2022)
Background: Cholangiocytes are primary targets in chronic cholestatic liver diseases. Myocyte enhancer factor 2A (MEF2A) is a transcription factor with a crucial role in some fibrogenic diseases. However, whether it contributes to cholestatic liver f
Externí odkaz:
https://doaj.org/article/b67b4f60e2244e009d785fc2f422de29