Zobrazeno 1 - 10
of 81
pro vyhledávání: '"MEF, mouse embryonic fibroblast"'
Publikováno v:
Regenerative Therapy, Vol 18, Iss, Pp 117-126 (2021)
Regenerative Therapy
Regenerative Therapy
Introduction Currently, embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) can be induced to differentiate at the cellular level but not to form mature tissues or organs suitable for transplantation. ESCs/iPSCs form immature terat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0302a91815aa58e9988fab6419f42486
http://www.sciencedirect.com/science/article/pii/S2352320421000432
http://www.sciencedirect.com/science/article/pii/S2352320421000432
Publikováno v:
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences, Vol 28, Iss 11, Pp 6653-6673 (2021)
Saudi Journal of Biological Sciences, Vol 28, Iss 11, Pp 6653-6673 (2021)
Graphical abstract
Several plants have traditionally been used since antiquity to treat various gastroenteritis and respiratory symptoms similar to COVID-19 outcomes. The common symptoms of COVID-19 include fever or chills, cold, cough, flu, hea
Several plants have traditionally been used since antiquity to treat various gastroenteritis and respiratory symptoms similar to COVID-19 outcomes. The common symptoms of COVID-19 include fever or chills, cold, cough, flu, hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb3987308abcc1d8a8d204193a54c90
https://doi.org/10.1016/j.sjbs.2021.07.036
https://doi.org/10.1016/j.sjbs.2021.07.036
Autor:
Hui Liu, Sara Maimouni, Sara Coppola, Ye Zhang, Jianliang Shen, Yijun Wang, Shenglan Gao, Ying-Tang Gao, Fengmei Wang, Heineken Queen Daguplo, Wei-Xing Zong, Junrong Yan, Zhi Du, Fang Wang, Yongbo Wang, Peng Wang, Bin Yang, Qin Zhang, Grace L. Guo, Kesong Peng, Wen-Xing Ding, Weiwei Dai, Fei Tang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1369-1385 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1369-1385 (2021)
Background and Aims TRIM21 is a ubiquitin E3 ligase that is implicated in numerous biological processes including immune response, cell metabolism, redox homeostasis, and cancer development. We recently reported that TRIM21 can negatively regulate th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f585b89cd7f24b7e5100047070b705c
https://doi.org/10.1016/j.jcmgh.2021.01.007
https://doi.org/10.1016/j.jcmgh.2021.01.007
Autor:
Jennifer T. Saville, Ainslie L. K. Derrick-Roberts, Brett V. Johnson, Megan S. Lord, Maria Fuller, Ha Na Kim, Lachlan A. Jolly, Rebecca J. Lehmann, Sharon Byers
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 29, Iss, Pp 100811-(2021)
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports
Mucopolysaccharidosis type IIIA (MPS IIIA) is characterised by a progressive neurological decline leading to early death. It is caused by bi-allelic loss-of-function mutations in SGSH encoding sulphamidase, a lysosomal enzyme required for heparan sul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8319b125d94dfde1df85ea9122f3ab4d
http://www.sciencedirect.com/science/article/pii/S2214426921001063
http://www.sciencedirect.com/science/article/pii/S2214426921001063
Autor:
Michael D. Onken, Sarah E. Noda, Kevin M. Kaltenbronn, Cheryl Frankfater, Carol M. Makepeace, Nikki Fettig, Kisha D. Piggott, Philip L. Custer, Joseph E. Ippolito, Kendall J. Blumer
Publikováno v:
The Journal of Biological Chemistry
Metabolic reprogramming has been shown to occur in uveal melanoma (UM), the most common intraocular tumor in adults. Mechanisms driving metabolic reprogramming in UM are poorly understood. Elucidation of these mechanisms could inform development of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75e9c1da7a1bf50b5ce0880b781fb6f
http://europepmc.org/articles/PMC8761705
http://europepmc.org/articles/PMC8761705
Autor:
Salvatore Santamaria, Josefin Ahnström, Kazuhiro Yamamoto, Daniel R. Martin, Xiangyi Dong, Suneel S. Apte
Publikováno v:
JOURNAL OF BIOLOGICAL CHEMISTRY
The Journal of Biological Chemistry
The Journal of Biological Chemistry
A disintegrin-like and metalloprotease domain with thrombospondin type 1 motifs (ADAMTS)8 is a secreted protease, which was recently implicated in pathogenesis of pulmonary arterial hypertension (PAH). However, the substrate repertoire of ADAMTS8 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3115da798faea6b0b44fa4b59c972eb
Autor:
Anouk Becker, Chih Hang Anthony Tang, Djenet Bousbaine, Matthias C. Truttmann, Corey M. Porter, Angelina M. Bilate, Chih-Chi Andrew Hu, Charlotte Wijne, Bhaskar K. Chatterjee, Hidde L. Ploegh, Nicholas McCaul
Publikováno v:
The Journal of Biological Chemistry
Fic domain-containing AMP transferases (fic AMPylases) are conserved enzymes that catalyze the covalent transfer of AMP to proteins. This posttranslational modification regulates the function of several proteins, including the ER-resident chaperone G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8454b6a2fe50baa7e5b5675a4d56b5
http://europepmc.org/articles/PMC8441161
http://europepmc.org/articles/PMC8441161
Autor:
Edwin Antony, Urvashi Mahajan, Susana Gonzalo, Simona Graziano, Barbara Teodoro-Castro, Alessandro Vindigni, Sahiti Kuppa, Elena Shashkova, Jessica Jackson, Núria Coll-Bonfill
Publikováno v:
The Journal of Biological Chemistry
Lamin A/C provides a nuclear scaffold for compartmentalization of genome function that is important for genome integrity. Lamin A/C dysfunction is associated with cancer, aging, and degenerative diseases. The mechanisms whereby lamin A/C regulates ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41a81d1c7d4b7e8ad53fa68be97c006
https://pubmed.ncbi.nlm.nih.gov/34648766
https://pubmed.ncbi.nlm.nih.gov/34648766
Autor:
Sjoerd J L van Wijk, Anne-Kathrin Knuth, Stefanie Rösler, Barbara Schenk, Lisa Kowald, Simone Fulda
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 1, Pp 74-81 (2019)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Interferons (IFNs) are key players in the tumor immune response and act by inducing the expression of IFN-stimulated genes (ISGs). Here, we identify the mixed-lineage kinase domain-like pseudokinase (MLKL) as an ISG in various cancer cell lines. Both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5938629e1af1e96d676b42488b98ebbd
http://www.sciencedirect.com/science/article/pii/S1476558618304366
http://www.sciencedirect.com/science/article/pii/S1476558618304366
Publikováno v:
The Journal of Biological Chemistry
The aryl hydrocarbon receptor (AHR) is a transcription factor activated by exogenous halogenated polycyclic aromatic hydrocarbon compounds, including the environmental toxin TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin, and naturally occurring dietary a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73e2b5476cf6c1e1f9ee2bcbc8cd8049
https://pubmed.ncbi.nlm.nih.gov/34146543
https://pubmed.ncbi.nlm.nih.gov/34146543