Zobrazeno 1 - 10
of 2 247
pro vyhledávání: '"MED/04 PATOLOGIA GENERALE"'
Autor:
Giuseppe Di Mauro, Roberta Amoriello, Neus Lozano, Alberto Carnasciali, Daniele Guasti, Maurizio Becucci, Giada Cellot, Kostas Kostarelos, Clara Ballerini, Laura Ballerini
Publikováno v:
ACS Nano. 17:1965-1978
Publikováno v:
Current Atherosclerosis Reports. 24:995-1004
Purpose of Review Since the clinical benefit of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors occurs in a setting of reducing low-density lipoprotein-cholesterol (LDL-C) to unprecedentedly low levels, it becomes of interest to inve
Autor:
Samuele Notarbartolo, Sergio Abrignani
Publikováno v:
Seminars in Immunopathology. 44:883-901
CD4+and CD8+T lymphocytes mediate most of the adaptive immune response against tumors. Naïve T lymphocytes specific for tumor antigens are primed in lymph nodes by dendritic cells. Upon activation, antigen-specific T cells proliferate and differenti
Autor:
Fanny Pojero, Francesco Gervasi, Salvatore Davide Fiore, Anna Aiello, Sonia Bonacci, Rosalia Caldarella, Alessandro Attanzio, Giuseppina Candore, Calogero Caruso, Mattia Emanuela Ligotti, Antonio Procopio, Ignazio Restivo, Luisa Tesoriere, Mario Allegra, Giulia Accardi
Immunosenescence and inflammaging facilitate the insurgence of chronic diseases. The Mediterranean diet is a non-invasive intervention to improve the chronic low-grade inflammatory status associated with aging. Olive oil oleuropein (OLE) and hydroxyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3658::4705211760343fb287092addc937ce1e
https://hdl.handle.net/10447/599173
https://hdl.handle.net/10447/599173
Autor:
Ligotti, Mattia Emanuela, Accardi, Giulia, Aiello, Anna, Aprile, Stefano, Calabrò, Anna, Caldarella, Rosalia, Caruso, Calogero, Ciaccio, Marcello, Corsale, Anna Maria, Dieli, Francesco, Di Simone, Marta, Giammanco, Giovanni Maurizio, Mascarella, Chiara, Akbar, Arne N, Meraviglia, Serena, Candore, Giuseppina
The immunophenotype of oldest centenarians, i.e., semi- and supercentenarians, could provide important information about their ability to adapt to factors associated with immune changes, including ageing per se and chronic Cytomegalovirus infection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3658::f249e8a7486695257a921baf0c5bb5d5
https://hdl.handle.net/10447/601434
https://hdl.handle.net/10447/601434
Autor:
Martina Musella, Andrea Guarracino, Nicoletta Manduca, Claudia Galassi, Eliana Ruggiero, Alessia Potenza, Ester Maccafeo, Gwenola Manic, Luca Mattiello, Sara Soliman Abdel Rehim, Michele Signore, Marco Pietrosanto, Manuela Helmer-Citterich, Matteo Pallocca, Maurizio Fanciulli, Tiziana Bruno, Francesca De Nicola, Giacomo Corleone, Anna Di Benedetto, Cristiana Ercolani, Edoardo Pescarmona, Laura Pizzuti, Francesco Guidi, Francesca Sperati, Sara Vitale, Daniele Macchia, Massimo Spada, Giovanna Schiavoni, Fabrizio Mattei, Adele De Ninno, Luca Businaro, Valeria Lucarini, Laura Bracci, Eleonora Aricò, Giovanna Ziccheddu, Francesco Facchiano, Stefania Rossi, Massimo Sanchez, Alessandra Boe, Mauro Biffoni, Ruggero De Maria, Ilio Vitale, Antonella Sistigu
Publikováno v:
Nature Immunology. 23:1379-1392
Cancer stem cells (CSCs) are a subpopulation of cancer cells endowed with high tumorigenic, chemoresistant and metastatic potential. Nongenetic mechanisms of acquired resistance are increasingly being discovered, but molecular insights into the evolu
Publikováno v:
Current Atherosclerosis Reports. 24:791-801
Purpose of Review The aim of creating an orally active non-statin cholesterol-lowering drug was achieved with bempedoic acid, a small linear molecule providing both a significant low-density lipoprotein cholesterol (LDL-C) reduction and an anti-infla