Zobrazeno 1 - 10
of 1 125
pro vyhledávání: '"MEANINGFUL CHANGE"'
Determining meaningful thresholds for evaluating treatment efficacy in patients with alopecia areata
Autor:
Ernest H. Law, Nicole J. Williams, Dane Korver, Randall H. Bender, Debanjali Mitra, Gregor Schaefer, Lauren M. Nelson
Publikováno v:
JEADV Clinical Practice, Vol 3, Iss 4, Pp 1119-1131 (2024)
Abstract Background The Severity of Alopecia Tool (SALT) is a clinician‐reported outcome measure of scalp hair loss in alopecia areata (AA). Objectives To characterise the magnitudes of change in SALT scores corresponding to meaningful treatment be
Externí odkaz:
https://doaj.org/article/2cb9541bc0234dd5939ad852143bd8fb
Autor:
Nathan A. Clarke, Brendon Wong, Rachael Lawrance, Anders Ingelgård, Ingolf Griebsch, David Cella, Andrew Trigg
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract Background Breast cancer is one of the most common cancers in women. Patient-reported outcome measures are used to evaluate patients’ health-related quality of life in clinical breast cancer studies. This study evaluated the structure, val
Externí odkaz:
https://doaj.org/article/c8c133fb5818480080b343a7b39677fb
Autor:
William R. Lenderking, Yulia Savva, Mark J. Atkinson, Renee Campbell, Isabelle Chabot, Margaret Moline, Genevieve Meier, Charles M. Morin
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract Background The Insomnia Severity Index (ISI) is a widely used measure of insomnia severity. Various ISI research findings suggest different factor solutions and meaningful within-individual change (MWIC) to detect treatment response in patie
Externí odkaz:
https://doaj.org/article/7f9f97c9d0c94205b47b1870f1dab97e
Autor:
Sally Zingelman, Dominique A. Cadilhac, Joosup Kim, Marissa Stone, Sam Harvey, Carolyn Unsworth, Robyn O'Halloran, Deborah Hersh, Kathryn Mainstone, Sarah J. Wallace
Publikováno v:
Health Expectations, Vol 27, Iss 4, Pp n/a-n/a (2024)
ABSTRACT Introduction Outcome measurement instruments (OMIs) are used to gauge the effects of treatment. In post‐stroke aphasia rehabilitation, benchmarks for meaningful change are needed to support the interpretation of patient outcomes. This stud
Externí odkaz:
https://doaj.org/article/a77c5e4205e049c4b2e7fb38c5ae3ca0
Publikováno v:
Journal of Patient-Reported Outcomes, Vol 8, Iss 1, Pp 1-4 (2024)
Abstract Background As patient-reported outcome measures (PROMs) become available to clinicians for routine clinical decision-making, many wonder how to define a meaningful change in a patient’s PROM score. Some PROMs have a specific threshold that
Externí odkaz:
https://doaj.org/article/509b9573db38422ba1dd7483c2d8268f
Autor:
Rawan Tarawneh, Vernon S. Pankratz
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract CLARITY-AD is an 18-month, double-blinded, placebo-controlled, phase 3 trial which examined the safety and efficacy of the anti-amyloid agent, lecanemab, in mild cognitive impairment and mild dementia due to Alzheimer disease (AD). Lecanemab
Externí odkaz:
https://doaj.org/article/f65bc19e94974fe2bd35a2c16ac06002
Autor:
Nicole Chemaly, Mathieu Kuchenbuch, Théo Teng, Elodie Marie, Gianluca D'Onofrio, Tommaso Lo Barco, Isabella Brambilla, Silke Flege, Anne‐Sophie Hallet, Rima Nabbout
Publikováno v:
Epilepsia Open, Vol 9, Iss 1, Pp 388-396 (2024)
Abstract We aimed to identify caregivers' opinions on the outcome measures that matter in clinical trials in individuals with Dravet syndrome (DS). We conducted a prospective European multicenter study based on an 11 closed questions survey developed
Externí odkaz:
https://doaj.org/article/05f5880e27fe45268bf963808043bab8
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
ObjectivesThe objective of this research was to generate psychometric evidence supporting the myasthenia gravis (MG) symptoms patient-reported outcome (PRO) scales as a fit-for-purpose measure of severity of core symptoms of MG and provide informatio
Externí odkaz:
https://doaj.org/article/bec1fe3766134ae297bd3459e552a7f8
Publikováno v:
Patient Related Outcome Measures, Vol Volume 14, Pp 313-335 (2023)
Michael Chladek,1 Claire Burbridge,2 Elizabeth Gibbons,2 Tom Willgoss,3 Janice Smith,4 Susanne Clinch3 1Clinical Outcome Assessments, Clinical Outcomes Solutions LLC, Chicago, IL, USA; 2Clinical Outcome Assessments, Clinical Outcomes Solutions Ltd, F
Externí odkaz:
https://doaj.org/article/8e56604dc21645efb1c1675c108454fa
Publikováno v:
Patient Related Outcome Measures, Vol Volume 14, Pp 337-354 (2023)
Susanne Clinch,1 Stacie Hudgens,2 Elizabeth Gibbons,3 Tom Willgoss,1 Janice Smith,4 Ela Polek,5 Claire Burbridge3 1Patient Centered Outcomes Research, Roche Products Ltd, Welwyn Garden City, Hertfordshire, UK; 2Quantitative Sciences, Clinical Outcome
Externí odkaz:
https://doaj.org/article/a946b623d45d41a9b56dc01381e056b9