Výsledky vyhledávání - "ME. Gutierrez-Castillo"

Akademický článek

Focused ultrasound on the substantia nigra enables safe neurotensin-polyplex nanoparticle-mediated gene delivery to dopaminergic neurons intranasally and by blood circulation

Autor: Juan U. Mascotte-Cruz, Arturo Vera, Lorenzo Leija, Francisco E. Lopez-Salas, Michael Gradzielski, Joachim Koetz, Bismark Gatica-García, C. P. Rodríguez-Oviedo, Irais E. Valenzuela-Arzeta, Lourdes Escobedo, David Reyes-Corona, ME. Gutierrez-Castillo, Minerva Maldonado-Berny, Armando J. Espadas-Alvarez, Carlos E. Orozco-Barrios, Daniel Martinez-Fong

Publikováno v: Discover Nano, Vol 19, Iss 1, Pp 1-24 (2024)

Abstract Neurotensin-polyplex nanoparticles provide efficient gene transfection of nigral dopaminergic neurons when intracerebrally injected in preclinical trials of Parkinson’s disease because they do not cross the blood–brain barrier (BBB). The

Externí odkaz: https://doaj.org/article/50dc39fbb81043508cc35ba8c82dfc8a

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Akademický článek

Unilateral rNurr1-V5 transgene expression in nigral dopaminergic neurons mitigates bilateral neuropathology and behavioral deficits in parkinsonian rats with α-synucleinopathy

Autor: Bismark Gatica-Garcia, Michael J Bannon, Irma Alicia Martínez-Dávila, Luis O Soto-Rojas, David Reyes-Corona, Lourdes Escobedo, Minerva Maldonado-Berny, ME Gutierrez-Castillo, Armando J Espadas-Alvarez, Manuel A Fernandez-Parrilla, Juan U Mascotte-Cruz, CP Rodríguez-Oviedo, Irais E Valenzuela-Arzeta, Claudia Luna-Herrera, Francisco E Lopez-Salas, Jaime Santoyo-Salazar, Daniel Martinez-Fong

Publikováno v: Neural Regeneration Research, Vol 19, Iss 9, Pp 2057-2067 (2024)

[INLINE:1] Parkinsonism by unilateral, intranigral β-sitosterol β-D-glucoside administration in rats is distinguished in that the α-synuclein insult begins unilaterally but spreads bilaterally and increases in severity over time, thus replicating

Externí odkaz: https://doaj.org/article/9b9457524ca44836abbf77cbfbe9fce8

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