Zobrazeno 1 - 10
of 67
pro vyhledávání: '"MDSC, myeloid derived suppressor cells"'
Autor:
Ling-Wei Wang
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/a6b5b1f6390c4d5db6baf411277f2068
Autor:
Chiara Musiu, Francesca Lupo, Antonio Agostini, Gabriella Lionetto, Michele Bevere, Salvatore Paiella, Carmine Carbone, Vincenzo Corbo, Stefano Ugel, Francesco De Sanctis
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Despite the efforts, pancreatic ductal adenocarcinoma (PDAC) is still highly lethal. Therapeutic challenges reside in late diagnosis and establishment of peculiar tumor microenvironment (TME) supporting tumor outgrowth. This stromal landscape is high
Externí odkaz:
https://doaj.org/article/45ea383fc8e649cc854103c3a4f8f1fd
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/fd4267aaff8f4d3897eb2ac65a6cbe3f
Autor:
Yin Celeste Cheuk, Shihao Xu, Dong Zhu, Yongsheng Luo, Tian Chen, Juntao Chen, Jiawei Li, Yi Shi, Yi Zhang, Ruiming Rong
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Background: Accumulating evidence indicates that mesenchymal stem cells (MSCs) are precursors of myofibroblasts, which play a vital role in renal fibrosis. The close interaction between MSCs and other immune cells regulates the development of multipl
Externí odkaz:
https://doaj.org/article/ab3900a717c842a7af465ceae7f4a2ff
Autor:
Sultan Tousif, Yong Wang, Joshua Jackson, Kenneth P. Hough, John G. Strenkowski, Mohammad Athar, Victor J. Thannickal, Robert H. McCusker, Selvarangan Ponnazhagan, Jessy S. Deshane
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Regulatory B cells (Breg) are IL-10 producing subsets of B cells that contribute to immunosuppression in the tumor microenvironment (TME). Breg are elevated in patients with lung cancer; however, the mechanisms underlying Breg development and their f
Externí odkaz:
https://doaj.org/article/1942612f213d4139803771b8c0d5424a
Autor:
Khalil Khalaf, Doris Hana, Jadzia Tin-Tsen Chou, Chandpreet Singh, Andrzej Mackiewicz, Mariusz Kaczmarek
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The tumor microenvironment (TME) is a complex and ever-changing “rogue organ” composed of its own blood supply, lymphatic and nervous systems, stroma, immune cells and extracellular matrix (ECM). These complex components, utilizing both benign an
Externí odkaz:
https://doaj.org/article/f0ddcf318e8f48f7ba81c91c8d6f4875
Autor:
Pacôme Lecot, Matthieu Sarabi, Manuela Pereira Abrantes, Julie Mussard, Leo Koenderman, Christophe Caux, Nathalie Bendriss-Vermare, Marie-Cécile Michallet
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Neutrophils have been extensively described in the pathophysiology of autoimmune and infectious diseases. Accumulating evidence also suggests the important role of neutrophils in cancer progression through their interaction with cancer and immune cel
Externí odkaz:
https://doaj.org/article/3d9194726ca04b33a4dcf1b280e6681b
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Objective: To investigate the role of myeloid-derived suppressor cells (MDSC) in cancer progression after the stress of operative removal and the potential treatment value of MDSC depletion.Summary Background Data: Surgery is the most important treat
Externí odkaz:
https://doaj.org/article/fa18e325738a4f3498c7079eae9450a1
Autor:
Kerstin Junker, Oybek Khalmurzaev, Hagen Loertzer, Isabelle Ariane Bley, Katrin Thieser, Nicole Ludwig, Sigrun Smola, Viktoria Wagner, Heiko Wunderlich, Vsevolod Borisovich Matveev, Arndt Hartmann, Anabel Zwick, Philine Loertzer, Alexey Pryalukhin, Holger Kalthoff, Carsten Maik Naumann, Carol-Immanuel Geppert, Stefan Lohse, Muriel Charlotte Hans
Publikováno v:
Translational Oncology
Translational Oncology, Vol 15, Iss 1, Pp 101267-(2022)
Translational Oncology, Vol 15, Iss 1, Pp 101267-(2022)
Highlights • Elevated expression of Wnt pathway associated factors in HPV-positive penile cancer cells. • lacking nuclear beta-catenin translocation indicated an actively abrogated Wnt signaling. • elevated expression of the Wnt antagonist DKK1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c45b7c4b2cb28b9bba333158a6f866
Autor:
Iñaki F. Trocóniz, Juan Jose Perez-Ruixo, Xavier Woot de Trixhe, Eduardo Asín-Prieto, Kim Stuyckens, Zinnia P. Parra-Guillen, José David Gómez Mantilla, Joris Vandenbossche
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4997-5007 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4997-5007 (2021)
Graphical abstract
Highlights • Mechanistic model characterizing acute immune response and HBV system interactions. • Key role of the cellular and regulatory response triggering hepatitis B chronicity. • Modelling framework to easily incor
Highlights • Mechanistic model characterizing acute immune response and HBV system interactions. • Key role of the cellular and regulatory response triggering hepatitis B chronicity. • Modelling framework to easily incor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::722cc9968b8cd803c557713cd9269da2
http://europepmc.org/articles/PMC8449028
http://europepmc.org/articles/PMC8449028