Zobrazeno 1 - 10
of 3 823
pro vyhledávání: '"MDSC"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Glioblastoma (GBM) is a malignant astrocytic tumor and its progression involves the regulation of vascular endothelial growth factor-A (VEGFA). However, the mechanism of VEGFA in regulating GBM progression remains unclear. Methods
Externí odkaz:
https://doaj.org/article/f92603400b7e48cb8541712ef534d2d7
Autor:
Safaa H. El-Taweel
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract The impact of adding ethylene vinyl acetate copolymer (EVA 80) and 1 wt% TiO2 nanoparticles on the morphology and crystallization behavior of poly(lactic acid) blends was investigated using DSC, SEM, and POM. Thermal analysis revealed the en
Externí odkaz:
https://doaj.org/article/26503541f227420599d2e0cb47f14223
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 7, Pp 830-838 (2024)
Tumor microenvironment (TME) is a complex cellular environment where tumor cells reside, along with various types of cells and extracellular components surrounding the tumor cells. Immune cells are key components of TME, including tumor-associated ma
Externí odkaz:
https://doaj.org/article/8b7c54b7f8e0499f8c03c4638141bdbf
Autor:
Tianxiang Hu, Bo Cheng, Atsuko Matsunaga, Ting Zhang, Xiaocui Lu, Hui Fang, Stephanie F. Mori, Xuexiu Fang, Gavin Wang, Hongyan Xu, Huidong Shi, John K. Cowell
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-20 (2024)
Abstract Background Leukemias driven by activated, chimeric FGFR1 kinases typically progress to AML which have poor prognosis. Mouse models of this syndrome allow detailed analysis of cellular and molecular changes occurring during leukemogenesis. We
Externí odkaz:
https://doaj.org/article/4bb949b779d9401693749daf13e351b5
Autor:
Anne-Béatrice Notarantonio, Allan Bertrand, Romain Piucco, Ghislain Fievet, Hervé Sartelet, Laura Boulangé, Natalia de Isla, Marcelo De Carvalho Bittencourt, Sébastien Hergalant, Marie-Thérèse Rubio, Maud D’Aveni
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-6 (2024)
Abstract Background Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only curative treatment for myeloid malignancies such as some acute myeloid leukemias (AML) and high-risk myelodysplastic syndromes (MDS). It aims to eradicate
Externí odkaz:
https://doaj.org/article/93db9b55384743518fd9aa8c038be339
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37060- (2024)
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by producing remarkable clinical outcomes for patients with various cancer types. However, only a subset of patients benefits from immunotherapeutic interventions due to the pri
Externí odkaz:
https://doaj.org/article/44896130478948b7baea88728551d416
Publikováno v:
Heliyon, Vol 10, Iss 16, Pp e36016- (2024)
Objective: Osteosarcoma (OS) is the most common primary bone sarcoma with a high propensity for local invasion and metastasis. Although the antitumor effect of apatinib has been well confirmed in advanced OS, the synergistic effect of apatinib and im
Externí odkaz:
https://doaj.org/article/37b033263c1d415ab2e2c2a4a5697dba
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Ovarian cancer is currently the second most common malignant tumor among gynecological cancers worldwide, primarily due to challenges in early diagnosis, high recurrence rates, and resistance to existing treatments. Current therapeutic options are in
Externí odkaz:
https://doaj.org/article/89685efe4b9f41e5a9fa61656c22798d
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117040- (2024)
Invariant natural killer T cell (iNKT) cells produce large amounts of cytokines in response to α-Galactosylceramide (α-GalCer) stimulation. An analog containing two phenyl rings on the acyl chain, C34, was previously found to be more Th1-biased tha
Externí odkaz:
https://doaj.org/article/af79b31128db4c6c9d8b7b90e3895a42
Autor:
Valéria Lima Kaminski, Bruno Montanari Borges, Bianca Vieira Santos, Nycolas Willian Preite, Vera Lucia Garcia Calich, Flávio Vieira Loures
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
BackgroundParacoccidioidomycosis (PCM) is a systemic endemic fungal disease prevalent in Latin America. Previous studies revealed that host immunity against PCM is tightly regulated by several suppressive mechanisms mediated by tolerogenic plasmacyto
Externí odkaz:
https://doaj.org/article/11d84f92488b4fcf9accbaf4d1190a89