Zobrazeno 1 - 10
of 53
pro vyhledávání: '"MCAO, middle cerebral artery occlusion"'
Autor:
Haigang Li, Yi Zhou, Luanfeng Liao, Hongyi Tan, Yejun Li, Zibo Li, Bilan Zhou, Meihua Bao, Binsheng He
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Aim: In China, warfarin is usually prescribed with Chuanxiong Rhizoma for treating thromboembolism diseases. However, the reason for their combination is still being determined. The present study explored the pharmacokinetics interactions of warfarin
Externí odkaz:
https://doaj.org/article/d40f067c431e4ffe91187d6e557fe533
Autor:
Lane J. Liddle, Christine A. Dirks, Brittany A. Fedor, Mohammed Almekhlafi, Frederick Colbourne
Publikováno v:
Frontiers in Neurology, Vol 11 (2021)
Background: As not all ischemic stroke patients benefit from currently available treatments, there is considerable need for neuroprotective co-therapies. Therapeutic hypothermia is one such co-therapy, but numerous issues have hampered its clinical u
Externí odkaz:
https://doaj.org/article/198455bf679d4d7b99419aa7a7b8c75e
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 7, Pp 1767-1788 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Ischemic stroke is a cerebrovascular disease normally caused by interrupted blood supply to the brain. Ischemia would initiate the cascade reaction consisted of multiple biochemical events in the damaged areas of the brain, where the ischemic cascade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f69f164eb91d122d8129e948fdf80fcb
http://www.sciencedirect.com/science/article/pii/S2211383520308194
http://www.sciencedirect.com/science/article/pii/S2211383520308194
Autor:
Xueyuan Yang, Soo K. Shin, Jin Xie, Kylee J. Duberstein, Madison M. Fagan, Simon R. Platt, Kelly M. Scheulin, Erin E. Kaiser, Holly A. Kinder, Elizabeth S. Waters, Julie Jeon, Franklin D. West, Anil Kumar, Hea Jin Park
Publikováno v:
IBRO Neuroscience Reports
IBRO Neuroscience Reports, Vol 10, Iss, Pp 18-30 (2021)
IBRO Neuroscience Reports, Vol 10, Iss, Pp 18-30 (2021)
Background The absolute number of new stroke patients is annually increasing and there still remains only a few Food and Drug Administration (FDA) approved treatments with significant limitations available to patients. Tanshinone IIA (Tan IIA) is a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f797c86f00c6b2f76590c2d6fd382a6
http://europepmc.org/articles/PMC8019951
http://europepmc.org/articles/PMC8019951
Akademický článek
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Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 2, Pp 239-248 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Nowadays, nanotechnology is revolutionizing the approaches to different fields from manufacture to health. Carbon nanotubes (CNTs) as promising candidates in nanomedicine have great potentials in developing novel entities for central nervous system p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::733fff34f30ef2de86219e20aec8517f
http://www.sciencedirect.com/science/article/pii/S2211383519306069
http://www.sciencedirect.com/science/article/pii/S2211383519306069
Autor:
Aftab Alam, Abuzer Ali, Mohd Amir, Farhan Jalees Ahmad, Wasim Ahmad, Niyaz Ahmad, Rizwan Ahmad
Publikováno v:
Saudi Journal of Biological Sciences, Vol 27, Iss 1, Pp 500-517 (2020)
Saudi Journal of Biological Sciences
Saudi Journal of Biological Sciences
Graphical abstract
Objective Here, the aim is to improve the bioavailability of Naringenin (NRG) in brain and to establish the highest remedial benefit from a novel anti-ischemic medicine i.e. NRG. Methods A novel Naringenin-loaded-nanoemulsion
Objective Here, the aim is to improve the bioavailability of Naringenin (NRG) in brain and to establish the highest remedial benefit from a novel anti-ischemic medicine i.e. NRG. Methods A novel Naringenin-loaded-nanoemulsion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbf9305501d6bea3502fb47e997e300
http://www.sciencedirect.com/science/article/pii/S1319562X19302402
http://www.sciencedirect.com/science/article/pii/S1319562X19302402
Autor:
Arina G. Shokhina, Gijsbert J. van Belle, A. A. Borodinova, Dörthe M. Katschinski, Vsevolod V. Belousov, M. S. Pochechuev, Aleksei M. Zheltikov, Anastasiya S. Panova, Roman I. Raevskii, Viktor S. Tarabykin, Marcus Conrad, Ilya V. Kelmanson, Thorsten R. Doeppner, Valeriy V. Pak, Aleksandr A. Moshchenko, Ivan Bogeski, Alexandra Ivanova, Yulia G. Ermakova, Maxim A. Solotenkov, Ilya V. Fedotov, Daria A. Kotova, Pavel M. Balaban, E. A. Stepanov, Dmitry S. Bilan, Mathias Bähr, Andrei B. Fedotov, Alexander I. Kostyuk
Publikováno v:
Redox Biol. 48:102178 (2021)
Redox Biology
Redox Biology, Vol 48, Iss, Pp 102178-(2021)
Redox Biology
Redox Biology, Vol 48, Iss, Pp 102178-(2021)
Ischemic cerebral stroke is one of the leading causes of death and disability in humans. However, molecular processes underlying the development of this pathology remain poorly understood. There are major gaps in our understanding of metabolic change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5efeb3d788e8ec892843d2b9cf08ecc
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63520
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63520
Autor:
Hongquan Guo, Xinfeng Liu, Juanji Li, Xiaolei Shi, Yi Xie, Pengfei Xu, Yunzi Li, Qian Liu, Rui Sun, Ye Hong, Mengna Peng, Gelin Xu
Publikováno v:
Redox Biology
Redox Biology, Vol 18, Iss, Pp 158-172 (2018)
Redox Biology, Vol 18, Iss, Pp 158-172 (2018)
Cellular oxidative stress plays a vital role in the pathological process of neural damage in cerebral ischemia/reperfusion (I/R). The breast cancer susceptibility protein 1 (BRCA1), a tumor suppressor, can modulate cellular antioxidant response and D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e034e7c5102b1e7cd98f372f511aac
https://doi.org/10.1016/j.redox.2018.06.012
https://doi.org/10.1016/j.redox.2018.06.012
Autor:
Xiaozhong Qu, Zhenzhong Yang, Haiqiang Jin, Yuanyuan Liu, Wei Cui, Yongan Sun, Hongjun Hao, Yining Huang, Yuming Teng, Mengnan Li, Ding Nan, Pu Lv, Chenghe Fan
Publikováno v:
Bioactive Materials, Vol 3, Iss 1, Pp 102-109 (2018)
Bioactive Materials
Bioactive Materials
The urokinase-type plasminogen activator (uPA) loaded hollow nanogels (nUK) were synthesized by a one-step reaction of glycol chitosan and aldehyde capped poly (ethylene oxide). The resultant formulation is sensitive to diagnostic ultrasound (US) of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6bb1f9e9e459d9c227cf201d447a691
http://www.sciencedirect.com/science/article/pii/S2452199X17300737
http://www.sciencedirect.com/science/article/pii/S2452199X17300737