In-Vitro Antiviral Activities of Extracts of Plants of The Brazilian Cerrado against the Avian Metapneumovirus (aMPV)

Autor: LK Kohn, MA Foglio, RA Rodrigues, IM de O Sousa, MC Martini, MA Padilla, DF de Lima Neto, CW Arns

Publikováno v: Brazilian Journal of Poultry Science, Vol 17, Iss 3, Pp 275-280 (2015)

ABSTRACTAvian metapneumovirus (aMPV) is a negative-sense single-stranded RNA enveloped virus of the Metapneumovirus genus belonging to theParamyxoviridae family. This virus may cause significant economic losses to the poultry industry, despite vaccin

Externí odkaz: https://doaj.org/article/2d0b040ab8694255b5eec56717adc00c

Mycobacterial RNase E cleaves with a distinct sequence preference and controls the degradation rates of most Mycolicibacterium smegmatis mRNAs.

Autor: Zhou Y; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, USA., Sun H; Program in Bioinformatics and Computational Biology, Worcester Polytechnic Institute, Worcester, Massachusetts, USA., Rapiejko AR; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, USA., Vargas-Blanco DA; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, USA., Martini MC; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, USA., Chase MR; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA., Joubran SR; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, USA., Davis AB; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, USA., Dainis JP; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, USA., Kelly JM; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, USA., Ioerger TR; Department of Computer Science & Engineering, Texas A&M University, College Station, Texas, USA., Roberts LA; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, USA., Fortune SM; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA., Shell SS; Department of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, Massachusetts, USA. Electronic address: sshell@wpi.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2023 Nov; Vol. 299 (11), pp. 105312. Date of Electronic Publication: 2023 Oct 05.

SARS-CoV-2 uses CD4 to infect T helper lymphocytes.

Autor: Brunetti NS; Autoimmune Research Laboratory, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Davanzo GG; Laboratory of Immunometabolism, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., de Moraes D; Laboratory of Aging Biology, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil.; Department of Structural and Functional Biology, Institute of Biosciences, Sao Paulo State University (UNESP), Botucatu, Brazil., Ferrari AJR; Institute of Chemistry and Center for Computing in Engineering and Sciences, University of Campinas, Campinas (UNICAMP), Campinas, Brazil., Souza GF; Laboratory of Emerging Viruses, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Muraro SP; Laboratory of Emerging Viruses, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Knittel TL; Laboratory of Aging Biology, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Boldrini VO; Autoimmune Research Laboratory, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Monteiro LB; Laboratory of Immunometabolism, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Virgílio-da-Silva JV; Laboratory of Immunometabolism, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Profeta GS; Laboratory of Aging Biology, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Wassano NS; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Nunes Santos L; Brazilian Laboratory on Silencing Technologies (BLaST), Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Carregari VC; Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Dias AHS; Institute of Chemistry and Center for Computing in Engineering and Sciences, University of Campinas, Campinas (UNICAMP), Campinas, Brazil., Veras FP; Center of Research in Inflammatory Diseases, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.; Department of BioMolecular Sciences, School of Pharmaceutical Sciences, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto,, São Paulo, Brazil., Tavares LA; Department of Cell and Molecular Biology, Center for Virology Research, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Forato J; Laboratory of Emerging Viruses, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Castro IMS; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil., Silva-Costa LC; Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Palma AC; Department of Internal Medicine, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil., Mansour E; Department of Internal Medicine, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil., Ulaf RG; Department of Internal Medicine, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil., Bernardes AF; Department of Internal Medicine, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil., Nunes TA; Department of Internal Medicine, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil., Ribeiro LC; Department of Internal Medicine, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil., Agrela MV; Department of Internal Medicine, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil., Moretti ML; Department of Internal Medicine, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil., Buscaratti LI; Brazilian Laboratory on Silencing Technologies (BLaST), Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Crunfli F; Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Ludwig RG; Laboratory of Aging Biology, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Gerhardt JA; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Munhoz-Alves N; Autoimmune Research Laboratory, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Marques AM; Autoimmune Research Laboratory, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Sesti-Costa R; Autoimmune Research Laboratory, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil.; Hematology and Hemotherapy Center, University of Campinas (UNICAMP), Campinas, Brazil., Amorim MR; Laboratory of Emerging Viruses, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Toledo-Teixeira DA; Laboratory of Emerging Viruses, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Parise PL; Laboratory of Emerging Viruses, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Martini MC; Laboratory of Emerging Viruses, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Bispos-Dos-Santos K; Laboratory of Emerging Viruses, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Simeoni CL; Laboratory of Emerging Viruses, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Granja F; Laboratory of Emerging Viruses, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Silvestrini VC; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., de Oliveira EB; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Faca VM; Department of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil., Carvalho M; National Biosciences Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.; Brazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil., Castelucci BG; National Biosciences Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil.; Brazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil., Pereira AB; National Biosciences Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil., Coimbra LD; National Biosciences Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil., Dias MMG; National Biosciences Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil., Rodrigues PB; Laboratory of Immunoinflammation, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil;, Campinas, Brazil., Gomes ABSP; Laboratory of Immunoinflammation, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil;, Campinas, Brazil., Pereira FB; Hematology and Hemotherapy Center, University of Campinas (UNICAMP), Campinas, Brazil., Santos LMB; Neuroimmunology Unit, Department of Genetics, Microbiology and Immunology, University of Campinas (UNICAMP), Campinas, Brazil.; National Institute of Science and Technology on Neuroimmunomodulation (INCT-NIM) - Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil., Bloyet LM; Washington University in St Louis, Department of Molecular Microbiology, St. Louis, United States., Stumpf S; Washington University in St Louis, Department of Molecular Microbiology, St. Louis, United States., Pontelli MC; Washington University in St Louis, Department of Molecular Microbiology, St. Louis, United States., Whelan S; Washington University in St Louis, Department of Molecular Microbiology, St. Louis, United States., Sposito AC; Laboratory of Vascular Biology and Arteriosclerosis, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil., Carvalho RF; Department of Structural and Functional Biology, Institute of Biosciences, Sao Paulo State University (UNESP), Botucatu, Brazil., Vieira AS; Laboratory of Electrophysiology, Neurobiology and Behavior, University of Campinas (UNICAMP), Campinas, Brazil., Vinolo MAR; Laboratory of Immunoinflammation, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil;, Campinas, Brazil.; Experimental Medicine Research Cluster (EMRC), University of Campinas (UNICAMP), Campinas, Brazil.; Obesity and Comorbidities Research Center (OCRC), University of Campinas (UNICAMP), Campinas, Brazil., Damasio A; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil.; Experimental Medicine Research Cluster (EMRC), University of Campinas (UNICAMP), Campinas, Brazil., Velloso L; Department of Internal Medicine, School of Medical Sciences, University of Campinas (UNICAMP), Campinas, Brazil.; Obesity and Comorbidities Research Center (OCRC), University of Campinas (UNICAMP), Campinas, Brazil., Figueira ACM; National Biosciences Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil., da Silva LLP; Center of Research in Inflammatory Diseases, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Cunha TM; Center of Research in Inflammatory Diseases, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto,, São Paulo, Brazil., Nakaya HI; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil., Marques-Souza H; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil.; Brazilian Laboratory on Silencing Technologies (BLaST), Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil., Marques RE; National Biosciences Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, Brazil., Martins-de-Souza D; Laboratory of Neuroproteomics, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil.; Experimental Medicine Research Cluster (EMRC), University of Campinas (UNICAMP), Campinas, Brazil.; D'Or Institute for Research and Education (IDOR), São Paulo, Brazil.; National Institute of Science and Technology in Biomarkers for Neuropsychiatry (INCTINBION), São Paulo, Brazil., Skaf MS; Institute of Chemistry and Center for Computing in Engineering and Sciences, University of Campinas, Campinas (UNICAMP), Campinas, Brazil., Proenca-Modena JL; Laboratory of Emerging Viruses, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil.; Experimental Medicine Research Cluster (EMRC), University of Campinas (UNICAMP), Campinas, Brazil., Moraes-Vieira PMM; Laboratory of Immunometabolism, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil.; Experimental Medicine Research Cluster (EMRC), University of Campinas (UNICAMP), Campinas, Brazil.; Obesity and Comorbidities Research Center (OCRC), University of Campinas (UNICAMP), Campinas, Brazil., Mori MA; Laboratory of Aging Biology, Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil.; Experimental Medicine Research Cluster (EMRC), University of Campinas (UNICAMP), Campinas, Brazil.; Obesity and Comorbidities Research Center (OCRC), University of Campinas (UNICAMP), Campinas, Brazil., Farias AS; Autoimmune Research Laboratory, Department of Genetics, Microbiology and Immunology, Institute of Biology, University of Campinas (UNICAMP), Campinas, Brazil.; Washington University in St Louis, Department of Molecular Microbiology, St. Louis, United States.; Experimental Medicine Research Cluster (EMRC), University of Campinas (UNICAMP), Campinas, Brazil.; Obesity and Comorbidities Research Center (OCRC), University of Campinas (UNICAMP), Campinas, Brazil.

Publikováno v: ELife [Elife] 2023 Jul 31; Vol. 12. Date of Electronic Publication: 2023 Jul 31.

SARS-CoV-2 infects adipose tissue in a fat depot- and viral lineage-dependent manner.

Autor: Saccon TD; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Mousovich-Neto F; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Ludwig RG; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Carregari VC; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Dos Anjos Souza AB; Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil., Dos Passos ASC; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.; Center for Research in Inflammatory Diseases, Ribeirão Preto, SP, Brazil., Martini MC; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Barbosa PP; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., de Souza GF; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Muraro SP; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Forato J; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Amorim MR; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Marques RE; Brazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, SP, Brazil., Veras FP; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.; Center for Research in Inflammatory Diseases, Ribeirão Preto, SP, Brazil.; Department of Biomolecular Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, SP, Brazil., Barreto E; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.; Center for Research in Inflammatory Diseases, Ribeirão Preto, SP, Brazil., Gonçalves TT; Center for Research in Inflammatory Diseases, Ribeirão Preto, SP, Brazil.; Department of Pharmacology, Faculty of Medical Sciences, University of Campinas, Campinas, SP, Brazil., Paiva IM; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.; Center for Research in Inflammatory Diseases, Ribeirão Preto, SP, Brazil., Fazolini NPB; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Onodera CMK; Hematology-Hemotherapy Center, University of Campinas, Campinas, SP, Brazil., Martins Junior RB; Virology Research Center, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil., de Araújo PHC; Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil., Batah SS; Department of Pathology and Legal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil., Viana RMM; Virology Research Center, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil., de Melo DM; Virology Research Center, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil., Fabro AT; Department of Pathology and Legal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil., Arruda E; Virology Research Center, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil., Queiroz Cunha F; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.; Center for Research in Inflammatory Diseases, Ribeirão Preto, SP, Brazil., Cunha TM; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil.; Center for Research in Inflammatory Diseases, Ribeirão Preto, SP, Brazil., Pretti MAM; Laboratory of Bioinformatics and Computational Biology, Division of Experimental and Translational Research, Brazilian National Cancer Institute (INCA), Rio de Janeiro, Brazil., Smith BJ; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Marques-Souza H; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Knittel TL; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Ruiz GP; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Profeta GS; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil., Fontes-Cal TCM; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil.; Obesity and Comorbidities Research Center (OCRC), University of Campinas, Campinas, SP, Brazil., Boroni M; Laboratory of Bioinformatics and Computational Biology, Division of Experimental and Translational Research, Brazilian National Cancer Institute (INCA), Rio de Janeiro, Brazil.; Experimental Medicine Research Cluster (EMRC), University of Campinas, Campinas, SP, Brazil., Vinolo MAR; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, SP, Brazil.; Obesity and Comorbidities Research Center (OCRC), University of Campinas, Campinas, SP, Brazil.; Experimental Medicine Research Cluster (EMRC), University of Campinas, Campinas, SP, Brazil., Farias AS; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, SP, Brazil.; Obesity and Comorbidities Research Center (OCRC), University of Campinas, Campinas, SP, Brazil.; Experimental Medicine Research Cluster (EMRC), University of Campinas, Campinas, SP, Brazil., Moraes-Vieira PMM; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, SP, Brazil.; Obesity and Comorbidities Research Center (OCRC), University of Campinas, Campinas, SP, Brazil.; Experimental Medicine Research Cluster (EMRC), University of Campinas, Campinas, SP, Brazil., Bizzacchi JMA; Hematology-Hemotherapy Center, University of Campinas, Campinas, SP, Brazil., Teesalu T; Laboratory of Precision and Nanomedicine, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia., Chaim FDM; Department of Surgery, Faculty of Medical Sciences, University of Campinas, Campinas, SP, Brazil., Cazzo E; Department of Surgery, Faculty of Medical Sciences, University of Campinas, Campinas, SP, Brazil., Chaim EA; Department of Surgery, Faculty of Medical Sciences, University of Campinas, Campinas, SP, Brazil., Proença-Módena JL; Department of Genetics, Evolution, Microbiology and Immunology, Institute of Biology, University of Campinas, Campinas, SP, Brazil.; Experimental Medicine Research Cluster (EMRC), University of Campinas, Campinas, SP, Brazil., Martins-de-Souza D; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil. dmsouza@unicamp.br.; Obesity and Comorbidities Research Center (OCRC), University of Campinas, Campinas, SP, Brazil. dmsouza@unicamp.br.; Experimental Medicine Research Cluster (EMRC), University of Campinas, Campinas, SP, Brazil. dmsouza@unicamp.br.; D'Or Institute for Research and Education (IDOR), São Paulo, SP, Brazil. dmsouza@unicamp.br.; Instituto Nacional de Biomarcadores em Neuropsiquiatria, Conselho Nacional de Desenvolvimento Científico e Tecnológico, São Paulo, SP, Brazil. dmsouza@unicamp.br., Osako MK; Department of Cell and Molecular Biology and Pathogenic Bioagents, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil. mko@fmrp.usp.br., Leiria LO; Department of Pharmacology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil. luizleiria@usp.br.; Center for Research in Inflammatory Diseases, Ribeirão Preto, SP, Brazil. luizleiria@usp.br., Mori MA; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil. morima@unicamp.br.; Obesity and Comorbidities Research Center (OCRC), University of Campinas, Campinas, SP, Brazil. morima@unicamp.br.; Experimental Medicine Research Cluster (EMRC), University of Campinas, Campinas, SP, Brazil. morima@unicamp.br.; Instituto Nacional de Obesidade e Diabetes, Conselho Nacional de Desenvolvimento Científico e Tecnológico, Campinas, SP, Brazil. morima@unicamp.br.

Publikováno v: Nature communications [Nat Commun] 2022 Sep 29; Vol. 13 (1), pp. 5722. Date of Electronic Publication: 2022 Sep 29.

Morphological, cellular, and molecular basis of brain infection in COVID-19 patients.

Autor: Crunfli F; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Carregari VC; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Veras FP; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Silva LS; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Nogueira MH; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Antunes ASLM; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Vendramini PH; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Valença AGF; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Brandão-Teles C; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Zuccoli GDS; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Reis-de-Oliveira G; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Silva-Costa LC; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Saia-Cereda VM; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Smith BJ; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Codo AC; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., de Souza GF; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Muraro SP; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Parise PL; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Toledo-Teixeira DA; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Santos de Castro ÍM; University of São Paulo, São Paulo, 05508-220, Brazil., Melo BM; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Almeida GM; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Firmino EMS; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Paiva IM; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Silva BMS; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Guimarães RM; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Mendes ND; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Ludwig RL; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Ruiz GP; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Knittel TL; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Davanzo GG; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Gerhardt JA; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Rodrigues PB; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Forato J; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Amorim MR; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Brunetti NS; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Martini MC; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Benatti MN; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Batah SS; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Siyuan L; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., João RB; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Aventurato ÍK; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Rabelo de Brito M; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Mendes MJ; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., da Costa BA; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Alvim MKM; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., da Silva Júnior JR; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Damião LL; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., de Sousa IMP; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., da Rocha ED; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Gonçalves SM; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Lopes da Silva LH; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Bettini V; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Campos BM; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Ludwig G; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Tavares LA; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Pontelli MC; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Viana RMM; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Martins RB; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Vieira AS; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Alves-Filho JC; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Arruda E; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Podolsky-Gondim GG; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Santos MV; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Neder L; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Damasio A; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Rehen S; D'Or Institute for Research and Education, 04502001, Brazil.; Institute of Biomedical Science, Federal University of Rio de Janeiro, Rio de Janeiro, 21941590, Brazil., Vinolo MAR; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Munhoz CD; University of São Paulo, São Paulo, 05508-220, Brazil., Louzada-Junior P; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Oliveira RD; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Cunha FQ; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Nakaya HI; University of São Paulo, São Paulo, 05508-220, Brazil., Mauad T; University of São Paulo, São Paulo, 05508-220, Brazil., Duarte-Neto AN; University of São Paulo, São Paulo, 05508-220, Brazil., Ferraz da Silva LF; University of São Paulo, São Paulo, 05508-220, Brazil., Dolhnikoff M; University of São Paulo, São Paulo, 05508-220, Brazil., Saldiva PHN; University of São Paulo, São Paulo, 05508-220, Brazil., Farias AS; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Cendes F; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Moraes-Vieira PMM; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Fabro AT; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Sebollela A; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Proença-Modena JL; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Yasuda CL; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Mori MA; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil., Cunha TM; Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, 14049900, Brazil., Martins-de-Souza D; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, 13083862, Brazil.; D'Or Institute for Research and Education, 04502001, Brazil.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2022 Aug 30; Vol. 119 (35), pp. e2200960119. Date of Electronic Publication: 2022 Aug 11.