CPC-032 Clopidogrel For the Treatment of Children with a Systemic-To-Pulmonary Arterial Shunt

Autor: A Pompilio, L Carloni, Amf Garzone, P Colonna, MC Cerlesi, P Marzioni, E Franchi, F Pinto, M Buccolini, E Andresciani, V Moretti, De Meo, F Ciuccarelli

Publikováno v: European Journal of Hospital Pharmacy. 20:A177.1-A177

Background Clopidogrel is a thienopyridine drug that acts by binding selectively and irreversibly to the adenosine diphosphate P2Y12 receptor on platelets. Platelet aggregation is consequently inhibited. Clopidogrel is used to prevent ischemic events

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d30d2a280a009559c37ececf437d5ce1
https://doi.org/10.1136/ejhpharm-2013-000276.489

A diastereoselective synthesis of Cebranopadol, a novel analgesic showing NOP/mu mixed agonism.

Autor: Fantinati A; Department of Chemical and Pharmaceutical Sciences and LTTA, University of Ferrara, 44121, Ferrara, Italy., Bianco S; Department of Chemical and Pharmaceutical Sciences and LTTA, University of Ferrara, 44121, Ferrara, Italy., Guerrini R; Department of Chemical and Pharmaceutical Sciences and LTTA, University of Ferrara, 44121, Ferrara, Italy., Salvadori S; Department of Chemical and Pharmaceutical Sciences and LTTA, University of Ferrara, 44121, Ferrara, Italy., Pacifico S; Department of Chemical and Pharmaceutical Sciences and LTTA, University of Ferrara, 44121, Ferrara, Italy., Cerlesi MC; Department of Medical Sciences, Section of Pharmacology and National Institute of Neuroscience, University of Ferrara, 44121, Ferrara, Italy., Calo G; Department of Medical Sciences, Section of Pharmacology and National Institute of Neuroscience, University of Ferrara, 44121, Ferrara, Italy., Trapella C; Department of Chemical and Pharmaceutical Sciences and LTTA, University of Ferrara, 44121, Ferrara, Italy. trap@unife.it.

Publikováno v: Scientific reports [Sci Rep] 2017 May 25; Vol. 7 (1), pp. 2416. Date of Electronic Publication: 2017 May 25.

Structure- and conformation-activity studies of nociceptin/orphanin FQ receptor dimeric ligands.

Autor: Pacifico S; Department of Chemical and Pharmaceutical Sciences and LTTA, University of Ferrara, 44121 Ferrara, Italy., Carotenuto A; Department of Pharmacy, University of Naples 'Federico II', 80131 Naples, Italy., Brancaccio D; Department of Agraria (QuaSic.A.Tec.), Università Mediterranea di Reggio Calabria, 89122 - Reggio Calabria, Italy., Novellino E; Department of Pharmacy, University of Naples 'Federico II', 80131 Naples, Italy., Marzola E; Department of Chemical and Pharmaceutical Sciences and LTTA, University of Ferrara, 44121 Ferrara, Italy., Ferrari F; Department of Medical Sciences, Section of Pharmacology and National Institute of Neuroscience, University of Ferrara, 44121 Ferrara, Italy., Cerlesi MC; Department of Medical Sciences, Section of Pharmacology and National Institute of Neuroscience, University of Ferrara, 44121 Ferrara, Italy., Trapella C; Department of Chemical and Pharmaceutical Sciences and LTTA, University of Ferrara, 44121 Ferrara, Italy., Preti D; Department of Chemical and Pharmaceutical Sciences and LTTA, University of Ferrara, 44121 Ferrara, Italy., Salvadori S; Department of Chemical and Pharmaceutical Sciences and LTTA, University of Ferrara, 44121 Ferrara, Italy., Calò G; Department of Medical Sciences, Section of Pharmacology and National Institute of Neuroscience, University of Ferrara, 44121 Ferrara, Italy., Guerrini R; Department of Chemical and Pharmaceutical Sciences and LTTA, University of Ferrara, 44121 Ferrara, Italy.

Publikováno v: Scientific reports [Sci Rep] 2017 Apr 06; Vol. 7, pp. 45817. Date of Electronic Publication: 2017 Apr 06.

In vitro functional characterization of novel nociceptin/orphanin FQ receptor agonists in recombinant and native preparations.

Autor: Ferrari F; Section of Pharmacology, Department of Medical Sciences, and National Institute of Neurosciences, University of Ferrara, Italy., Cerlesi MC; Section of Pharmacology, Department of Medical Sciences, and National Institute of Neurosciences, University of Ferrara, Italy., Malfacini D; Section of Pharmacology, Department of Medical Sciences, and National Institute of Neurosciences, University of Ferrara, Italy., Asth L; Behavioral Pharmacology Laboratory, Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Natal, RN, Brazil., Gavioli EC; Behavioral Pharmacology Laboratory, Department of Biophysics and Pharmacology, Federal University of Rio Grande do Norte, Natal, RN, Brazil., Journigan BV; Astraea Therapeutics, LLC. 320 Logue Avenue, Mountain View, CA, USA., Kamakolanu UG; Astraea Therapeutics, LLC. 320 Logue Avenue, Mountain View, CA, USA., Meyer ME; Astraea Therapeutics, LLC. 320 Logue Avenue, Mountain View, CA, USA., Yasuda D; Astraea Therapeutics, LLC. 320 Logue Avenue, Mountain View, CA, USA., Polgar WE; SRI International, Biosciences Division, 333 Ravenswood Avenue, Menlo Park, CA, USA., Rizzi A; Section of Pharmacology, Department of Medical Sciences, and National Institute of Neurosciences, University of Ferrara, Italy., Guerrini R; Department of Chemical and Pharmaceutical Sciences and LTTA, University of Ferrara, Italy., Ruzza C; Section of Pharmacology, Department of Medical Sciences, and National Institute of Neurosciences, University of Ferrara, Italy., Zaveri NT; Astraea Therapeutics, LLC. 320 Logue Avenue, Mountain View, CA, USA., Calo G; Section of Pharmacology, Department of Medical Sciences, and National Institute of Neurosciences, University of Ferrara, Italy. Electronic address: g.calo@unife.it.

Publikováno v: European journal of pharmacology [Eur J Pharmacol] 2016 Dec 15; Vol. 793, pp. 1-13. Date of Electronic Publication: 2016 Oct 22.

Characterisation of the Novel Mixed Mu-NOP Peptide Ligand Dermorphin-N/OFQ (DeNo).

Autor: Bird MF; Department of Cardiovascular Sciences, University of Leicester, Division of Anaesthesia, Critical Care and Pain Management, Leicester Royal Infirmary, Leicester, LE2 7LX, United Kingdom., Cerlesi MC; Department of Medical Sciences, Section of Pharmacology and National Institute of Neuroscience, University of Ferrara, Ferrara, Italy., Brown M; Department of Cardiovascular Sciences, University of Leicester, Division of Anaesthesia, Critical Care and Pain Management, Leicester Royal Infirmary, Leicester, LE2 7LX, United Kingdom., Malfacini D; Department of Medical Sciences, Section of Pharmacology and National Institute of Neuroscience, University of Ferrara, Ferrara, Italy., Vezzi V; Department of Pharmacology, Istituto Superiore di Sanità, Rome, 00161, Italy., Molinari P; Department of Pharmacology, Istituto Superiore di Sanità, Rome, 00161, Italy., Micheli L; Department of Neuroscience, Psychology, Drug Research and Child Health-Neurofarba, Pharmacology and Toxicology Section, University of Florence, Florence, Italy., Di Cesare Mannelli L; Department of Neuroscience, Psychology, Drug Research and Child Health-Neurofarba, Pharmacology and Toxicology Section, University of Florence, Florence, Italy., Ghelardini C; Department of Neuroscience, Psychology, Drug Research and Child Health-Neurofarba, Pharmacology and Toxicology Section, University of Florence, Florence, Italy., Guerrini R; Department of Chemical and Pharmaceutical Sciences and LTTA, University of Ferrara, Ferrara, Italy., Calò G; Department of Medical Sciences, Section of Pharmacology and National Institute of Neuroscience, University of Ferrara, Ferrara, Italy., Lambert DG; Department of Cardiovascular Sciences, University of Leicester, Division of Anaesthesia, Critical Care and Pain Management, Leicester Royal Infirmary, Leicester, LE2 7LX, United Kingdom.

Publikováno v: PloS one [PLoS One] 2016 Jun 07; Vol. 11 (6), pp. e0156897. Date of Electronic Publication: 2016 Jun 07 (Print Publication: 2016).