Zobrazeno 1 - 10
of 23
pro vyhledávání: '"MC, methylcellulose"'
Autor:
Bert Chi, Andrew Patron, Michael Saganich, Sara Werner, Catherine Tachdjian, Guy Servant, Amy J. Arthur, Joseph R. Fotsing, Lily Ida, Hanghui Liu, Donald S. Karanewsky
Publikováno v:
Toxicology Reports, Vol 4, Iss, Pp 507-520 (2017)
Toxicology Reports
Toxicology Reports
Graphical abstract The results of the ADME, genotoxicity, rodent toxicology and developmental toxicology studies conducted on a new flavour compound S2218 are reported. S2218 is a positive allosteric modifier (PAM) of the human sweet taste receptor a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcdef84c8da13f7445a16395430628f3
https://doi.org/10.1016/j.toxrep.2017.09.004
https://doi.org/10.1016/j.toxrep.2017.09.004
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 5, Pp 850-860 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Organic anion transporting polypeptide 1B1 and 1B3 (OATP1B1/3) as important uptake transporters play a fundamental role in the transportation of exogenous drugs and endogenous substances into cells. Rat OATP1B2, encoded by the Slco1b2 gene, is homolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3274f81619e66696d12472ba24e85de1
https://pubmed.ncbi.nlm.nih.gov/32528832
https://pubmed.ncbi.nlm.nih.gov/32528832
Publikováno v:
Regenerative Therapy, Vol 3, Iss C, Pp 11-14 (2016)
Regenerative Therapy
Regenerative Therapy
We have previously reported that multi-cellular heteroaggregates comprising murine pancreatic α (αTC1.6) and β (MIN6-m9) cell lines spontaneously acquired islet-like architecture and displayed higher insulin secretion rates. However, the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c02a1eb58481b1c6aba33ebe28acf42
Publikováno v:
Regenerative Therapy
Regenerative Therapy, Vol 3, Iss C, Pp 7-10 (2016)
Regenerative Therapy, Vol 3, Iss C, Pp 7-10 (2016)
Introduction Three-dimensional (3D) multicellular spheroids are useful tools for simulation of cellular functions in vitro. However, it is difficult to culture certain epithelial cell types under 3D spheroid conditions because these cells cannot resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8cd641bc98ed7827bfab1402e8f06b
https://doi.org/10.1016/j.reth.2016.01.007
https://doi.org/10.1016/j.reth.2016.01.007
Autor:
Takumi Takahashi, Miki Maehara, Genya Mitani, Masato Sato, Eriko Toyoda, Masahiko Watanabe, Yoshihiko Nakamura, Tomonori Takagaki, Kosuke Hamahashi
Publikováno v:
Regenerative Therapy
Regenerative Therapy, Vol 10, Iss, Pp 17-26 (2019)
Regenerative Therapy, Vol 10, Iss, Pp 17-26 (2019)
Introduction Cartilage regeneration is a promising therapy for restoring joint function in patients with cartilage defects. The limited availability of autologous chondrocytes or chondrogenic progenitor cells is an obstacle to its clinical applicatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bbacb01d9f60f1d44ab465e22902063
https://pubmed.ncbi.nlm.nih.gov/30525067
https://pubmed.ncbi.nlm.nih.gov/30525067
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 2, Iss C, Pp 1255-1264 (2015)
Toxicology Reports, Vol 2, Iss C, Pp 1255-1264 (2015)
A toxicological evaluation of 4-amino-5-(3-(isopropylamino)-2,2-dimethyl-3-oxopropoxy)-2-methylquinoline-3-carboxylic acid(S9632; CAS 1359963-68-0), a flavour with modifying properties,was completed for the purpose of assessing its safety for use in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::699c950a8ce0809acd4c14174d604f5f
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 3, Iss, Pp 501-512 (2016)
Scipedia Open Access
Scipedia SL
Toxicology Reports, Vol 3, Iss, Pp 501-512 (2016)
Scipedia Open Access
Scipedia SL
A toxicological evaluation of a umami flavour compound, 2-(((3-(2,3-dimethoxyphenyl)-1H-1,2,4-triazol-5-yl)thio)methyl)pyridine (S3643; CAS 902136-79-2), was completed for the purpose of assessing its safety for use in food and beverage applications.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6a45e67d6f656c14275d47a9c3954d9
https://www.scipedia.com/public/Karanewsky_et_al_2016a
https://www.scipedia.com/public/Karanewsky_et_al_2016a
Publikováno v:
Toxicology Reports
Toxicological evaluations of two N-alkyl benzamide umami flavour compounds, N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide (S807, CAS 745047-51-2) and (R)-N-(1-methoxy-4-methylpentan-2-yl)-3,4-dimethylbenzamide (S9229, CAS 851669-60-8), were compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::524e0c72486864471f513cad6066e211
https://pubmed.ncbi.nlm.nih.gov/28959612
https://pubmed.ncbi.nlm.nih.gov/28959612
Publikováno v:
Toxicology Reports
A toxicological evaluation of two novel bitter modifying flavour compounds, 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H-pyrazol-4-yl)-1-(3-hydroxybenzyl)imidazolidine-2,4-dione (S6821, CAS 1119831-25-2) and 3-(1-((3,5-dimethylisoxazol-4-yl)methyl)-1H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e63193896cb3992b91bcd0805ba9f48
https://pubmed.ncbi.nlm.nih.gov/28959552
https://pubmed.ncbi.nlm.nih.gov/28959552
Publikováno v:
Regenerative Therapy
A three-dimensional (3D) bone marrow (BM) culture system may facilitate research into the molecular mechanisms involved in hematopoiesis and BM diseases. However, because >90% of BM cells are composed of non-adherent blood cells, it is difficult to o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::355b85b19571596464eeea4534d5cf4b
https://pubmed.ncbi.nlm.nih.gov/31245470
https://pubmed.ncbi.nlm.nih.gov/31245470