Single and two-dose typhoid conjugate vaccine safety and immunogenicity in HIV-exposed uninfected and HIV-unexposed uninfected Malawian children.

Autor: Nampota-Nkomba N; Blantyre Malaria Project, Kamuzu University of Health Sciences, Blantyre, Malawi.; Graduate Program in Life Sciences, University of Maryland School of Medicine, Baltimore, MD, USA., Nyirenda OM; Blantyre Malaria Project, Kamuzu University of Health Sciences, Blantyre, Malawi., Mapemba V; Blantyre Malaria Project, Kamuzu University of Health Sciences, Blantyre, Malawi., Masonga R; Blantyre Malaria Project, Kamuzu University of Health Sciences, Blantyre, Malawi., Patel PD; Malawi-Liverpool-Wellcome Program, Kamuzu University of Health Sciences, Blantyre, Malawi., Misiri T; Malawi-Liverpool-Wellcome Program, Kamuzu University of Health Sciences, Blantyre, Malawi., Mwakiseghile F; Malawi-Liverpool-Wellcome Program, Kamuzu University of Health Sciences, Blantyre, Malawi., Wachepa R; Malawi-Liverpool-Wellcome Program, Kamuzu University of Health Sciences, Blantyre, Malawi., Ndaferankhande JM; Malawi-Liverpool-Wellcome Program, Kamuzu University of Health Sciences, Blantyre, Malawi., Lipenga B; Malawi-Liverpool-Wellcome Program, Kamuzu University of Health Sciences, Blantyre, Malawi., Patel P; Malawi-Liverpool-Wellcome Program, Kamuzu University of Health Sciences, Blantyre, Malawi., Banda H; Malawi-Liverpool-Wellcome Program, Kamuzu University of Health Sciences, Blantyre, Malawi., Oshinsky J; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA., Pasetti MF; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA., Heyderman RS; Malawi-Liverpool-Wellcome Program, Kamuzu University of Health Sciences, Blantyre, Malawi.; Department of Infection, Division of Infectious Diseases, University College London, London, UK., Jamka LP; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA., Hosangadi D; Graduate Program in Life Sciences, University of Maryland School of Medicine, Baltimore, MD, USA., Datta S; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA., Gordon MA; Malawi-Liverpool-Wellcome Program, Kamuzu University of Health Sciences, Blantyre, Malawi.; Malawi-Liverpool-Wellcome Program, University of Liverpool, Liverpool, UK., Neuzil KM; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA.; Fogarty International Center, National Institute of Health, Bethesda, MD, USA., Laurens MB; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA.

Publikováno v: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2024 Dec 31; Vol. 20 (1), pp. 2384760. Date of Electronic Publication: 2024 Sep 12.

Children with hemoglobin C or S trait have low serologic responses to a subset of malaria variant surface antigens.

Autor: Bailey RD; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., HSF1 Room 480, Baltimore, MD 21201, United States of America. Electronic address: rbailey@som.umaryland.edu., Lawton JG; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., HSF1 Room 480, Baltimore, MD 21201, United States of America. Electronic address: JLawton@som.umaryland.edu., Niangaly A; Malaria Research and Training Center, University Science, Techniques and Technologies of Bamako, BP 1805, Point G, Bamako, Mali. Electronic address: niangaly@mrtcbko.org., Stucke EM; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., HSF1 Room 480, Baltimore, MD 21201, United States of America. Electronic address: Emily.Stucke@umaryland.edu., Bailey JA; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., HSF1 Room 480, Baltimore, MD 21201, United States of America. Electronic address: JBailey@som.umaryland.edu., Berry AA; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., HSF1 Room 480, Baltimore, MD 21201, United States of America. Electronic address: aberry@som.umaryland.edu., Ouattara A; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., HSF1 Room 480, Baltimore, MD 21201, United States of America. Electronic address: amouattara@som.umaryland.edu., Coulibaly D; Malaria Research and Training Center, University Science, Techniques and Technologies of Bamako, BP 1805, Point G, Bamako, Mali. Electronic address: coulibalyd@icermali.org., Lyke KE; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., HSF1 Room 480, Baltimore, MD 21201, United States of America. Electronic address: klyke@som.umaryland.edu., Laurens MB; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., HSF1 Room 480, Baltimore, MD 21201, United States of America. Electronic address: MLaurens@som.umaryland.edu., Zhou AE; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., HSF1 Room 480, Baltimore, MD 21201, United States of America. Electronic address: Albert.Zhou@som.umaryland.edu., Pablo J; Division of Infectious Diseases, Department of Medicine, University of California, 101 The City Drive, Orange, CA 92868, United States of America. Electronic address: jozelynp@gmail.com., Jasinskas A; Division of Infectious Diseases, Department of Medicine, University of California, 101 The City Drive, Orange, CA 92868, United States of America. Electronic address: ajasinsk@uci.edu., Nakajima R; Division of Infectious Diseases, Department of Medicine, University of California, 101 The City Drive, Orange, CA 92868, United States of America. Electronic address: rie3@uci.edu., Adams M; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., HSF1 Room 480, Baltimore, MD 21201, United States of America. Electronic address: madams@som.umaryland.edu., Takala-Harrison S; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., HSF1 Room 480, Baltimore, MD 21201, United States of America. Electronic address: STakala@som.umaryland.edu., Kouriba B; Malaria Research and Training Center, University Science, Techniques and Technologies of Bamako, BP 1805, Point G, Bamako, Mali. Electronic address: kouriba@icermali.org., Kone AK; Malaria Research and Training Center, University Science, Techniques and Technologies of Bamako, BP 1805, Point G, Bamako, Mali. Electronic address: fankone@icermali.org., Guindo A; Malaria Research and Training Center, University Science, Techniques and Technologies of Bamako, BP 1805, Point G, Bamako, Mali. Electronic address: aldguindo@icermali.org., Rowe JA; Center for Immunity, Infection and Evolution, Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Charlotte Auerbach Road, Edinburgh EH9 3FL, United Kingdom. Electronic address: Alex.Rowe@ed.ac.uk., Diallo DA; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., HSF1 Room 480, Baltimore, MD 21201, United States of America. Electronic address: dadiallo@icermali.org., Doumbo OK; Malaria Research and Training Center, University Science, Techniques and Technologies of Bamako, BP 1805, Point G, Bamako, Mali. Electronic address: okd@icermali.org., Felgner PL; Division of Infectious Diseases, Department of Medicine, University of California, 101 The City Drive, Orange, CA 92868, United States of America. Electronic address: pfelgner@uci.edu., Plowe CV; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., HSF1 Room 480, Baltimore, MD 21201, United States of America. Electronic address: plowe.chris@gmail.com., Thera MA; Malaria Research and Training Center, University Science, Techniques and Technologies of Bamako, BP 1805, Point G, Bamako, Mali. Electronic address: mthera@icermali.org., Travassos MA; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, 685 W. Baltimore St., HSF1 Room 480, Baltimore, MD 21201, United States of America. Electronic address: mtravass@som.umaryland.edu.

Publikováno v: The Journal of infection [J Infect] 2024 Oct; Vol. 89 (4), pp. 106257. Date of Electronic Publication: 2024 Aug 30.

A new landscape for malaria vaccine development.

Autor: Laurenson AJ; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.; Molecular Microbiology and Immunology Program, Graduate Program in Life Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States of America., Laurens MB; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2024 Jun 27; Vol. 20 (6), pp. e1012309. Date of Electronic Publication: 2024 Jun 27 (Print Publication: 2024).

Gene expression analyses reveal differences in children's response to malaria according to their age.

Autor: Tebben K; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA., Yirampo S; Malaria Research and Training Center, University of Sciences, Techniques and Technologies, Bamako, Mali., Coulibaly D; Malaria Research and Training Center, University of Sciences, Techniques and Technologies, Bamako, Mali., Koné AK; Malaria Research and Training Center, University of Sciences, Techniques and Technologies, Bamako, Mali., Laurens MB; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA., Stucke EM; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA., Dembélé A; Malaria Research and Training Center, University of Sciences, Techniques and Technologies, Bamako, Mali., Tolo Y; Malaria Research and Training Center, University of Sciences, Techniques and Technologies, Bamako, Mali., Traoré K; Malaria Research and Training Center, University of Sciences, Techniques and Technologies, Bamako, Mali., Niangaly A; Malaria Research and Training Center, University of Sciences, Techniques and Technologies, Bamako, Mali., Berry AA; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA., Kouriba B; Malaria Research and Training Center, University of Sciences, Techniques and Technologies, Bamako, Mali., Plowe CV; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA., Doumbo OK; Malaria Research and Training Center, University of Sciences, Techniques and Technologies, Bamako, Mali., Lyke KE; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA., Takala-Harrison S; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA., Thera MA; Malaria Research and Training Center, University of Sciences, Techniques and Technologies, Bamako, Mali., Travassos MA; Malaria Research Program, Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA., Serre D; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA. dserre@som.umaryland.edu.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA. dserre@som.umaryland.edu.

Publikováno v: Nature communications [Nat Commun] 2024 Mar 06; Vol. 15 (1), pp. 2021. Date of Electronic Publication: 2024 Mar 06.

DON in pediatric cerebral malaria, a phase I/IIA dose-escalation safety study: study protocol for a clinical trial.

Autor: Nampota-Nkomba N; Blantyre Malaria Project, Kamuzu University of Health Sciences, Blantyre, Malawi., Nyirenda OM; Blantyre Malaria Project, Kamuzu University of Health Sciences, Blantyre, Malawi., Mallewa J; Department of Internal Medicine, Kamuzu University of Health Sciences, Blantyre, Malawi., Chimalizeni Y; Department of Paediatrics and Child Health, Kamuzu University of Health Sciences, Blantyre, Malawi., Dzabala N; Department of Pharmacy, Kamuzu University of Health Sciences, Blantyre, Malawi., Fay MP; Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA., Gopalakrishnan M; Center for Translational Medicine, University of Maryland School of Pharmacy, Baltimore, MD, USA., Laurens MB; Center for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, MD, USA., O'Brien NF; Department of Pediatrics, Division of Critical Care Medicine, Nationwide Children's Hospital, Columbus, OH, USA., Miller LH; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA., Pierce SK; Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA., Riggle BA; Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, USA. brittany.riggle@nih.gov., Postels DG; Division of Neurology, The George Washington University/ Children's National Medical Center, Washington, DC, USA. dpostels@childrensnational.org.

Publikováno v: Trials [Trials] 2024 Jan 26; Vol. 25 (1), pp. 87. Date of Electronic Publication: 2024 Jan 26.