Zobrazeno 1 - 10
of 57
pro vyhledávání: '"MB Finch"'
Publikováno v:
The European respiratory journal. 3(7)
Many immunological abnormalities, including circulating immune complexes (CICs), have been described in patients with sarcoidosis. The relationship of these abnormalities to clinical states is uncertain. In 31 proven cases of sarcoidosis we used the
Publikováno v:
British Journal of Clinical Pharmacology. 21:249-258
The beta-adrenoceptor blocking properties and cardioselectivity of ICI 141, 292 were investigated in healthy male subjects. Seven subjects received in random order oral doses of ICI 141,292 20, 50, 100, 200 and 400 mg, atenolol 50 and 100 mg and plac
Autor:
MB Finch, GD Johnston
Publikováno v:
British Journal of Clinical Pharmacology. 20:447-451
The acute effects of increasing doses of diltiazem on peripheral blood flow were observed in six subjects. Each subject received, in random order, a single oral dose of placebo or diltiazem 60, 120 or 180 mg. Supine heart rate, blood pressure, skin t
Publikováno v:
British Journal of Clinical Pharmacology. 16:451-455
Five healthy volunteers (mean age 20.6 years, mean weight 71 kg) received in random order on day 1 and day 8 a single dose of alinidine 40 mg, clonidine 0.1 mg or placebo and on days 2-7 alinidine 40 mg, clonidine 0.1 mg or placebo given three times
Publikováno v:
British Journal of Clinical Pharmacology. 21:359-364
The acute peripheral vascular and diuretic effects of intravenous frusemide 10 mg and 20 mg were compared with those of bumetanide 250 micrograms and 500 micrograms in a group of 10 salt depleted volunteers. Significant reductions in forearm blood fl
Publikováno v:
British Journal of Clinical Pharmacology. 17:353-355
The effects of maintenance indomethacin therapy on single dose digoxin pharmacokinetics and dynamics were studied in six healthy volunteers with normal renal function. Indomethacin did not alter the elimination half-life, systemic clearance or distri
Publikováno v:
British journal of clinical pharmacology. 19(4)
To examine the importance of acute frusemide-induced renin release in the production of the acute peripheral venous and arterial responses to frusemide in man, the effects of two drugs, previously described as inhibitors of acute frusemide-induced re
1 The present study compared the effects in healthy volunteers of the acute and chronic administration of placebo, pindolol and propranolol to see if the partial agonist activity of pindolol was reduced by the beta-adrenoceptor blocking activity of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b629563783365d31617fead7a03dd613
https://europepmc.org/articles/PMC1427788/
https://europepmc.org/articles/PMC1427788/
Autor:
A. N. Brown, D. G. McDevitt, PC O'Connor, Robin G. Shanks, J. M. O. Arnold, MB Finch, D. W. G. Harron, D. B. Galloway, R. J. Francis
Publikováno v:
British journal of clinical pharmacology. 19(3)
The pharmacokinetic and pharmacodynamic effects of Ro31-1118 were examined in groups of healthy volunteers. In three subjects given 10 mg of [14C]-Ro31-1118 orally, peak levels of radioactivity (84 +/- 5 ng/ml) were 16 times those of the parent drug
Publikováno v:
Clinical science (London, England : 1979). 65(4)
1. To examine the importance of angiotensin II formation in the production of frusemide's acute peripheral venous and arterial responses, the effect of pretreatment with captopril was studied. 2. Captopril abolished the acute increases in venous capa