Zobrazeno 1 - 10
of 102
pro vyhledávání: '"MAYA SALEH"'
Autor:
Simon Bissonnette, Valérie Lamantia, Benjamin Ouimet, Yannick Cyr, Marie Devaux, Remi Rabasa-Lhoret, Michel Chrétien, Maya Saleh, May Faraj
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Elevated plasma numbers of atherogenic apoB-lipoproteins (apoB), mostly as low-density lipoproteins (LDL), predict diabetes risk by unclear mechanisms. Upregulation of the NLRP3 inflammasome/interleukin-1 beta (IL-1β) system in white adipos
Externí odkaz:
https://doaj.org/article/0a83e95703d94c1093fe7679d3611bd4
Autor:
Julie Giraud, Domitille Chalopin, Eloïse Ramel, Thomas Boyer, Atika Zouine, Marie-Alix Derieppe, Nicolas Larmonier, Olivier Adotevi, Brigitte Le Bail, Jean-Frédéric Blanc, Christophe Laurent, Laurence Chiche, Marc Derive, Macha Nikolski, Maya Saleh
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113773- (2024)
Summary: Hepatocellular carcinoma (HCC) is an inflammation-associated cancer arising from viral or non-viral etiologies including steatotic liver diseases (SLDs). Expansion of immunosuppressive myeloid cells is a hallmark of inflammation and cancer,
Externí odkaz:
https://doaj.org/article/023f817342b74e968922605adf63aef4
Autor:
Allan Tran, Charlotte Scholtes, Mario Songane, Claudia Champagne, Luc Galarneau, Marie-Pier Levasseur, Nassima Fodil, Catherine Rosa Dufour, Vincent Giguère, Maya Saleh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The estrogen-related receptor alpha (ERRα) is a primary regulator of mitochondrial energy metabolism, function and dynamics, and has been implicated in autophagy and immune regulation. ERRα is abundantly expressed in the intestine and in c
Externí odkaz:
https://doaj.org/article/31be6f5a64804b909ef3f38b8309e70b
Autor:
Sebastian Lillo, Maya Saleh
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The inflammasomes are critical regulators of innate immunity, inflammation and cell death and have emerged as important regulators of cancer development and control. Inflammasomes are assembled by pattern recognition receptors (PRR) following the sen
Externí odkaz:
https://doaj.org/article/aa917a2b6b1d4d7ab711ac1acd02735c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The community of the diverse microorganisms residing in the gastrointestinal tract, known as the gut microbiota, is exceedingly being studied for its impact on health and disease. This community plays a major role in nutrient metabolism, maintenance
Externí odkaz:
https://doaj.org/article/4bca950123d649078c58bd50d9512d29
Autor:
Benjamin AWR Ralph, Melanie Lehoux, Hanna Ostapska, Brendan D. Snarr, Alayna K. Caffrey-Carr, Richard Fraser, Maya Saleh, Joshua J. Obar, Salman T. Qureshi, Donald C. Sheppard
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Aspergillus fumigatus airway infections are associated with increased rates of hospitalizations and declining lung function in patients with chronic lung disease. While the pathogenesis of invasive A. fumigatus infections is well studied, little is k
Externí odkaz:
https://doaj.org/article/d88a9100c3c944109606726bf7d86365
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Hepatocellular carcinoma (HCC) is the most common liver tumor and among the deadliest cancers worldwide. Advanced HCC overall survival is meager and has not improved over the last decade despite approval of several tyrosine kinase inhibitors (TKi) fo
Externí odkaz:
https://doaj.org/article/78944b22f11b4e14b0db4d7295a4281a
Autor:
Yannick Cyr, Valérie Lamantia, Simon Bissonnette, Melanie Burnette, Aurèle Besse‐Patin, Annie Demers, Martin Wabitsch, Michel Chrétien, Gaétan Mayer, Jennifer L. Estall, Maya Saleh, May Faraj
Publikováno v:
Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)
Abstract Background LDL‐cholesterol lowering variants that upregulate receptor uptake of LDL, such as in PCSK9 and HMGCR, are associated with diabetes via unclear mechanisms. Activation of the NLRP3 inflammasome/interleukin‐1 beta (IL‐1β) path
Externí odkaz:
https://doaj.org/article/55e8b3a5fa1f4be4a5bf58b8cf9bb904
Autor:
Gaël Galli, Maya Saleh
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2021)
Macrophages are important effectors of tissue homeostasis, inflammation and host defense. They are equipped with an arsenal of pattern recognition receptors (PRRs) necessary to sense microbial- or danger-associated molecular patterns (MAMPs/DAMPs) an
Externí odkaz:
https://doaj.org/article/24293f6b955f438da53257f35fafd1a0
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Glioblastoma (GBM) are the most common tumors of the central nervous system and among the deadliest cancers in adults. GBM overall survival has not improved over the last decade despite optimization of therapeutic standard-of-care. While immune check
Externí odkaz:
https://doaj.org/article/f0abd702e13a403688890fdf69e92725