Zobrazeno 1 - 10 of 35 pro vyhledávání: '"MAY TRUONGCAO"'
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Akademický článek
GPC3-mediated metabolic rewiring of diabetic mesenchymal stromal cells enhances their cardioprotective functions via PKM2 activation
Autor: Darukeshwara Joladarashi, Charan Thej, Vandana Mallaredy, Ajit Magadum, Maria Cimini, Carolina Gonzalez, May Truongcao, Joseph T. Nigro, Manveen K. Sethi, Andrew A. Gibb, Cindy Benedict, Walter J. Koch, Raj Kishore
Publikováno v: iScience, Vol 27, Iss 10, Pp 111021- (2024)
Summary: Mesenchymal stromal cells (MSC) are promising stem cell therapy for treating cardiovascular and other degenerative diseases. Diabetes affects the functional capability of MSC and impedes cell-based therapy. Despite numerous studies, the impa
Externí odkaz: https://doaj.org/article/3a9a8135cbdf48ae9273925cf1080a09
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5
Abstract P3081: Glypican 3 Regulates Diabetes Induced Mesenchymal Stromal Cells Dysfunctions
Autor: Darukeshwara Joladarashi, Charan T Gurrala, Ajit Magadum, Maria Cimini, Vandana Mallaredy, Carolina Gonzalez, Anna Maria Lucchese, May Truongcao, Chunlin Wang, Cindy Benedict, Zhongjian Cheng, Raj Kishore
Publikováno v: Circulation Research. 131
Mesenchymal stromal cells (MSC) based therapies are considered as an ideal stem cell-based treatment for cardiovascular diseases due to their immunosuppressive characteristics, anti-inflammatory properties, and differentiation potential. Diabetic mic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::51f4a68d766065a3574397a4a2ad158c
https://doi.org/10.1161/res.131.suppl_1.p3081
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6
Abstract P1128: Myocardial Delivery Of Modified Mrna For Exosomal Protein Induces Cardiac Regeneration
Autor: Ajit Magadum, Vandana Mallaredy, Rajika Roy, Chunlin Wang, Darukeshwara Joladarashi, Charan Thej Gurrala, Zhongjian Cheng, May Truongcao, Anna Maria Lucchese, Cindy Benedict, Vagner O Rigaud, Mohsin Khan, Raj Kishore
Publikováno v: Circulation Research. 131
Permanent loss of cardiomyocytes (CM) after myocardial infarction (MI) and limited cardiac regenerative capacity leads to heart failure. Recent studies from zebrafish, newt, and even 1-day old neonatal mice showed that they could regenerate their hea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b079ae220bfaf1ccfd0f817546914aa
https://doi.org/10.1161/res.131.suppl_1.p1128
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7
Abstract P2022: Tipifarnib Mediated Protection By Reduction Of Circulating Exosomes In Pressure Overloaded Cardiac Hypertrophy
Autor: Vandana Mallaredy, Rajika Roy, Zhongjian Cheng, Darukeshwara Joladarashi, Ajit Magadum, Charan Thej Gurrala, Maria Cimini, Grace Huang, Venkata Naga Srikanth Garikipati, Chunlin Wang, May Truongcao, Cindy Benedict, Carolina Gonzalez, Walter J Koch, Raj Kishore
Publikováno v: Circulation Research. 131
Hypertrophic cardiomyopathy (HCM) in response to pathophysiological stress is one of the leading causes of heart failure. A growing body of evidence emphasizes the crucial role of exosomes and their modulated content in aggravating cardiac damage due
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e52cd003f88dfa5f0572ed13b0d38b87
https://doi.org/10.1161/res.131.suppl_1.p2022
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8
Abstract P2053: Role Of Podoplanin Positive Cells Exosomes In Cardiac Inflammation And Amyloidosis
Autor: Maria Cimini, Carolina Gonzalez, Cagla Tukel, Mary Barbe, Anna Maria Lucchese, Chunlin Wang, MAY TRUONGCAO, Grace Huang, Andrea Elia, Vandana Mallaredy, Cindy Benedict, Raj Kishore
Publikováno v: Circulation Research. 131
The extra-cellular-matrix (ECM) composition of scar tissue after myocardial infarction (MI)has been largely investigated. Although fibronectin and collagen are favorable for newmyocyte formation, other components that may increase the scar stiffness
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5dfc413c5bc3b9dea73bbe90ff67cbc1
https://doi.org/10.1161/res.131.suppl_1.p2053
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9
Interleukin-10 Deficiency Alters Endothelial Progenitor Cell–Derived Exosome Reparative Effect on Myocardial Repair via Integrin-Linked Kinase Enrichment
Autor: Zhongjian Cheng, Maria Cimini, Chunlin Wang, Venkata Naga Srikanth Garikipati, Cindy Benedict, Rajika Roy, Yujia Yue, Grace Huang, Raj Kishore, May Truongcao, Walter J. Koch
Publikováno v: Circ Res
Rationale: Systemic inflammation compromises the reparative properties of endothelial progenitor cell (EPC) and their exosomes on myocardial repair, although the underlying mechanism of loss of function of exosomes from inflamed EPCs is still obscure
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b20b9c07ea0d0c16f4e4261fe87d36d
https://doi.org/10.1161/circresaha.119.315829
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10
Abstract 11286: Human-Induced Pluripotent Stem Cell Derived Exosomal Protein Induces Cardiac Regeneration
Autor: Ajit Magadum, Vandana Mallaredy, Rajika Roy, Darukeshwara Joladarashi, Charan Thej Gurrala, Zhongjian Cheng, Maria Cimini, Grace Huang, Chunlin Wang, Anna Maria Lucchese, May Truongcao, Cindy Benedict, Raj Kishore
Publikováno v: Circulation. 144
Introduction: Cardiovascular diseases are the leading causes of death worldwide. After myocardial infarction (MI), there is a permanent loss of cardiomyocytes (CMs), and as the mammalian heart has limited regenerative capacity, it leads to Heart Fail
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::996c33f2ab283b1280287abd8b343a8d
https://doi.org/10.1161/circ.144.suppl_1.11286
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