Zobrazeno 1 - 10
of 278
pro vyhledávání: '"MATTHIAS A. HEDIGER"'
Autor:
Jonai Pujol‐Giménez, Ghayda Mirzaa, Elizabeth E. Blue, Giuseppe Albano, Danny E. Miller, Aimee Allworth, James T. Bennett, Peter H. Byers, Sirisak Chanprasert, Jingheng Chen, Daniel Doherty, Andrew B. Folta, Madelyn A. Gillentine, Ian Glass, Anne Hing, Martha Horike‐Pyne, Kathleen A. Leppig, Azma Parhin, Jane Ranchalis, Wendy H. Raskind, Elisabeth A. Rosenthal, Ulrike Schwarze, Sam Sheppeard, Samuel Strohbehn, Virginia P. Sybert, Andrew Timms, Mark Wener, University of Washington Center for Mendelian Genomics (UW‐CMG)a, Undiagnosed Diseases Network (UDN), Michael J. Bamshad, Fuki M. Hisama, Gail P. Jarvik, Katrina M. Dipple, Matthias A. Hediger, Andrew B. Stergachis
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 6, Pp 1046-1053 (2023)
Abstract SLC1A4 is a trimeric neutral amino acid transporter essential for shuttling L‐serine from astrocytes into neurons. Individuals with biallelic variants in SLC1A4 are known to have spastic tetraplegia, thin corpus callosum, and progressive m
Externí odkaz:
https://doaj.org/article/7c78457d1e624c4ca4136b621b913e02
Autor:
Jonai Pujol-Giménez, Sven P. Baumann, Tin Manh Ho, Bartlomiej Augustynek, Matthias A. Hediger
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 771 (2024)
The peptide/histidine transporter PHT1 (SLC15A4) is expressed in the lysosomal membranes of immune cells where it plays an important role in metabolic and inflammatory signaling. PHT1 is an H+-coupled/histidine symporter that can transport a wide ran
Externí odkaz:
https://doaj.org/article/66fcbfc7ec1149e886b544ead8f811aa
Autor:
Palanivel Kandasamy, Inti Zlobec, Damian T. Nydegger, Jonai Pujol‐Giménez, Rajesh Bhardwaj, Senji Shirasawa, Toshiyuki Tsunoda, Matthias A. Hediger
Publikováno v:
Molecular Oncology, Vol 15, Iss 10, Pp 2782-2800 (2021)
Oncogenic KRAS mutations develop unique metabolic dependencies on nutrients to support tumor metabolism and cell proliferation. In particular, KRAS mutant cancer cells exploit amino acids (AAs) such as glutamine and leucine, to accelerate energy meta
Externí odkaz:
https://doaj.org/article/b6fc7ae16925449f8d9d9da78bd65412
Autor:
Jonas Zaugg, Jonai Pujol Giménez, Romina Silvia Cabra, Wilhelm Hofstetter, Matthias A. Hediger, Christiane Albrecht
Publikováno v:
CHIMIA, Vol 76, Iss 12 (2022)
The TransCure project entitled 'Iron Transporters DMT1 and FPN1' took an interdisciplinary approach combining structural biology, chemistry and physiology to gain new insights into iron transport. Proteins studied included Divalent Metal Transporter
Externí odkaz:
https://doaj.org/article/385c83b9963448e295b5e51816f86205
Autor:
Sami Havukainen, Jonai Pujol-Giménez, Mari Valkonen, Matthias A. Hediger, Christopher P. Landowski
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-20 (2021)
Abstract Background Lignocellulose biomass has been investigated as a feedstock for second generation biofuels and other value-added products. Some of the processes for biofuel production utilize cellulases and hemicellulases to convert the lignocell
Externí odkaz:
https://doaj.org/article/720301a9224049f8a88ab1ef4ee090c9
Autor:
Sami Havukainen, Jonai Pujol-Giménez, Mari Valkonen, Ann Westerholm-Parvinen, Matthias A. Hediger, Christopher P. Landowski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Trichoderma reesei is an ascomycete fungus known for its capability to secrete high amounts of extracellular cellulose- and hemicellulose-degrading enzymes. These enzymes are utilized in the production of second-generation biofuels and T. re
Externí odkaz:
https://doaj.org/article/a3f3643ea6a143de8f982d5be4fdd2fb
Autor:
Damian T. Nydegger, Jonai Pujol-Giménez, Palanivel Kandasamy, Bruno Vogt, Matthias A. Hediger
Publikováno v:
Viruses, Vol 15, Iss 7, p 1432 (2023)
As the COVID-19 pandemic progresses, new variants of SARS-CoV-2 continue to emerge. This underscores the need to develop optimized tools to study such variants, along with new coronaviruses that may arise in the future. Such tools will also be instru
Externí odkaz:
https://doaj.org/article/361b3b779b334dd38385edaad36bf202
Autor:
Sophia N. Verouti, Jonai Pujol-Giménez, Paola Bermudez-Lekerika, Laeticia Scherler, Rajesh Bhardwaj, Aurélien Thomas, Sébastien Lenglet, Mark Siegrist, Willy Hofstetter, Daniel G. Fuster, Matthias A. Hediger, Geneviève Escher, Bruno Vogt
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The metal ion transporter ZIP8 (SLC39A8) mediates cellular uptake of vital divalent metal ions. Genome-wide association studies (GWAS) showed that the single-nucleotide polymorphism (SNP) variant A391T (rs13107325) is associated with numerous human t
Externí odkaz:
https://doaj.org/article/4dd0962652ae49ec91bde16de4444a7d
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The SLC9 gene family encodes Na+/H+ exchangers (NHEs), a group of membrane transport proteins critically involved in the regulation of cytoplasmic and organellar pH, cell volume, as well as systemic acid-base and volume homeostasis. NHEs of the SLC9A
Externí odkaz:
https://doaj.org/article/3a4d224ddee94a589c4f07ffcc77b1d7
Autor:
Rajesh Bhardwaj, Bartłomiej S. Augustynek, Ebru Ercan-Herbst, Palanivel Kandasamy, Matthias Seedorf, Christine Peinelt, Matthias A. Hediger
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 2, Pp 252-270 (2020)
Externí odkaz:
https://doaj.org/article/849fcf9fda36415285c2f661c862b70e