Zobrazeno 1 - 10
of 158
pro vyhledávání: '"MATTHEW CARTER"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10425 (2024)
The binding of small molecules to sarcomeric myosin can elicit powerful effects on the chemomechanical cycle, making them effective therapeutics in the clinic and research tools at the benchtop. However, these myotropes can have complex effects that
Externí odkaz:
https://doaj.org/article/912518b6246e49c9ac6d5701a29948fb
Autor:
Ahmet Fuat, Emmanuel Ako, David Hargroves, Douglas Holden, Amrit Caleyachetty, Matthew Carter, James Harris, Carol Roberts, Nnanyelu Nzeakor, Burcu Vardar, Helen Williams
Publikováno v:
Journal of Market Access & Health Policy, Vol 11, Iss 1 (2023)
ABSTRACTObjective Direct oral anticoagulants (DOACs) are first-line therapy for stroke prevention for 1.4 million atrial fibrillation (AF) patients in the UK. However, the rates of DOAC dosing below evidence-based recommendations are estimated betwee
Externí odkaz:
https://doaj.org/article/d4a42c313ec6431dae5aa6bf519eaf1c
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
In chronic lymphocytic leukaemia (CLL), immune dysregulation is common and can manifest as immune thrombocytopenia (ITP). Corticosteroids are the mainstay for front-line management of CLL-associated ITP. Therapy refractoriness represents a clinical c
Externí odkaz:
https://doaj.org/article/a4a7699e92f24c6aacda9dabd5e5fc99
Autor:
Jessica X. Chong, Matthew Carter Childers, Colby T. Marvin, Anthony J. Marcello, Hernan Gonorazky, Lili-Naz Hazrati, James J. Dowling, Fatema Al Amrani, Yasemin Alanay, Yolanda Nieto, Miguel Á Marín Gabriel, Arthur S. Aylsworth, Kati J. Buckingham, Kathryn M. Shively, Olivia Sommers, Kailyn Anderson, Michael Regnier, Michael J. Bamshad
Publikováno v:
HGG Advances, Vol 4, Iss 3, Pp 100213- (2023)
Summary: Contraction of the human sarcomere is the result of interactions between myosin cross-bridges and actin filaments. Pathogenic variants in genes such as MYH7, TPM1, and TNNI3 that encode parts of the cardiac sarcomere cause muscle diseases th
Externí odkaz:
https://doaj.org/article/08f67d5e060d475c83319e61695d173d
Autor:
Matthew Carter
Publikováno v:
Religions, Vol 15, Iss 1, p 13 (2023)
Shakespeare’s Henry VI trilogy is jam-packed with spectacle: heads are severed and made to kiss, women dress as men and lead armies, ghosts predict the future, and a plethora of miracles take place all over the various locales we visit across fifte
Externí odkaz:
https://doaj.org/article/41e458988fad4607bd0db4883253f08c
Autor:
Simon W. Young, Nina Zeng, Mei Lin Tay, David Fulker, Christina Esposito, Matthew Carter, Ali Bayan, Bill Farrington, Rupert Van Rooyen, Matthew Walker
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Improving the functional outcome following total knee arthroplasty (TKA) by using different alignment techniques remains controversial. The surgical techniques and technologies used so far to obtain these alignments have all suffe
Externí odkaz:
https://doaj.org/article/3ce38bf9ee4c436ea03125758cee288e
Autor:
Conor Rosato, Robert E. Moore, Matthew Carter, John Heap, John Harris, Jose Storopoli, Simon Maskell
Publikováno v:
Information, Vol 14, Iss 3, p 170 (2023)
The emergence of the novel coronavirus (COVID-19) generated a need to quickly and accurately assemble up-to-date information related to its spread. In this research article, we propose two methods in which Twitter is useful when modelling the spread
Externí odkaz:
https://doaj.org/article/8026228b471d4c1a93253561dd51c4ec
Autor:
Athanasios R Paliouras, Marta Buzzetti, Lei Shi, Ian J Donaldson, Peter Magee, Sudhakar Sahoo, Hui‐Sun Leong, Matteo Fassan, Matthew Carter, Gianpiero Di Leva, Matthew G Krebs, Fiona Blackhall, Christine M Lovly, Michela Garofalo
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 7, Pp 1-16 (2020)
Abstract A subset of lung adenocarcinomas is driven by the EML4‐ALK translocation. Even though ALK inhibitors in the clinic lead to excellent initial responses, acquired resistance to these inhibitors due to on‐target mutations or parallel pathwa
Externí odkaz:
https://doaj.org/article/6544b05e1c244d05b4afe550ea63b803
Publikováno v:
Brain Multiphysics, Vol 3, Iss , Pp 100054- (2022)
During protein synthesis, aminoacyl-tRNA synthetases covalently link amino acids with their cognate tRNAs. Amino acid mutations in glycyl-tRNA synthetase can disrupt protein synthesis and lead to a neurological disorder known as Charcot-Marie-Tooth d
Externí odkaz:
https://doaj.org/article/692267c55c98424db67483c287042e74
Autor:
Justin Michael Clark, Sharon Sanders, Matthew Carter, David Honeyman, Gina Cleo, Yvonne Auld, Debbie Booth, Patrick Condron, Christine Dalais, Sarah Bateup, Bronwyn Linthwaite, Nikki May, Jo Munn, Lindy Ramsay, Kirsty Rickett, Cameron Rutter, Angela Smith, Peter Sondergeld, Margie Wallin, Mark Jones, Elaine Beller
Publikováno v:
Journal of the Medical Library Association, Vol 108, Iss 2 (2020)
Background: Searching for studies to include in a systematic review (SR) is a time- and labor-intensive process with searches of multiple databases recommended. To reduce the time spent translating search strings across databases, a tool called the P
Externí odkaz:
https://doaj.org/article/9fa1ba635adb4736a3b9ef6ae888d5bf