Zobrazeno 1 - 10
of 496
pro vyhledávání: '"MATTER PATHOLOGY"'
Autor:
Xiaoyun Xu, Matthew Cowan, Flavio Beraldo, Amy Schranz, Patrick McCunn, Nicole Geremia, Zalman Brown, Maitray Patel, Karen L. Nygard, Reza Khazaee, Lihong Lu, Xingyu Liu, Michael J. Strong, Gregory A. Dekaban, Ravi Menon, Robert Bartha, Mark Daley, Haojie Mao, Vania Prado, Marco A. M. Prado, Lisa Saksida, Tim Bussey, Arthur Brown
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-27 (2021)
Abstract We have previously reported long-term changes in the brains of non-concussed varsity rugby players using magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI) and functional magnetic imaging (fMRI). Others have reported cogni
Externí odkaz:
https://doaj.org/article/8a4b058cb2f44d0f99bb08a4296f09b7
Publikováno v:
NeuroImage: Clinical, Vol 29, Iss , Pp 102555- (2021)
Objective: Phenylketonuria (PKU) is an autosomal recessive disorder whereby deficiencies in phenylalanine metabolism cause progressive neurological dysfunction. Managing PKU is challenging, with disease monitoring focussed on short-term phenylalanine
Externí odkaz:
https://doaj.org/article/fb5db6c61ae74cd0bfee97d7ea7b4b0e
Autor:
Josine E. G. Vaes, Marit A. Vink, Caroline G. M. de Theije, Freek E. Hoebeek, Manon J. N. L. Benders, Cora H. A. Nijboer
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Diffuse white matter injury (dWMI) is a major cause of morbidity in the extremely preterm born infant leading to life-long neurological impairments, including deficits in cognitive, motor, sensory, psychological, and behavioral functioning. At presen
Externí odkaz:
https://doaj.org/article/09e936b3a0154045b4efc4a5b7a70fd5
Akademický článek
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Autor:
Sygrid van der Zee, Jeffrey M. Boertien, Gilles N. Stormezand, Teus van Laar, Muhammad Nazmuddin, Jan-Willem van Dalen, Harm J. van der Horn, Ronald Borra
Publikováno v:
Parkinsonism & Related Disorders, 93, 43-49
Parkinsonism & Related Disorders, 93, 43-49. Elsevier
Parkinsonism & Related Disorders, 93, pp. 43-49
Parkinsonism & Related Disorders, 93, 43-49. Elsevier
Parkinsonism & Related Disorders, 93, pp. 43-49
INTRODUCTION: The postural instability gait difficulty motor subtype of patients with Parkinson's disease (PIGD-PD) has been associated with more severe cognitive pathology and a higher risk on dementia compared to the tremor-dominant subtype (TD-PD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07bace3e33f6930987f537dbfec0c904
https://doi.org/10.1016/j.parkreldis.2021.11.010
https://doi.org/10.1016/j.parkreldis.2021.11.010
Autor:
Man, Jodie H.K., van Gelder, Charlotte A.G.H., Breur, Marjolein, Okkes, Daniel, Molenaar, Douwe, van der Sluis, Sophie, Abbink, Truus, Altelaar, Maarten, van der Knaap, Marjo S., Bugiani, Marianna, Afd Biomol.Mass Spect. and Proteomics, Biomolecular Mass Spectrometry and Proteomics
Publikováno v:
Cells, 11(22):3581, 1-19. MDPI Multidisciplinary Digital Publishing Institute
Cells, 11(22):3581. MDPI Multidisciplinary Digital Publishing Institute
Cells; Volume 11; Issue 22; Pages: 3581
Man, J H K, van Gelder, C A G H, Breur, M, Okkes, D, Molenaar, D, van der Sluis, S, Abbink, T, Altelaar, M, van der Knaap, M S & Bugiani, M 2022, ' Cortical Pathology in Vanishing White Matter ', Cells, vol. 11, no. 22, 3581 . https://doi.org/10.3390/cells11223581
Man, J H K, van Gelder, C A G H, Breur, M, Okkes, D, Molenaar, D, van der Sluis, S, Abbink, T, Altelaar, M, van der Knaap, M S & Bugiani, M 2022, ' Cortical Pathology in Vanishing White Matter ', Cells, vol. 11, no. 22, 3581, pp. 1-19 . https://doi.org/10.3390/cells11223581
Cells, 11(22), 1. Multidisciplinary Digital Publishing Institute (MDPI)
Cells, 11(22):3581. MDPI Multidisciplinary Digital Publishing Institute
Cells; Volume 11; Issue 22; Pages: 3581
Man, J H K, van Gelder, C A G H, Breur, M, Okkes, D, Molenaar, D, van der Sluis, S, Abbink, T, Altelaar, M, van der Knaap, M S & Bugiani, M 2022, ' Cortical Pathology in Vanishing White Matter ', Cells, vol. 11, no. 22, 3581 . https://doi.org/10.3390/cells11223581
Man, J H K, van Gelder, C A G H, Breur, M, Okkes, D, Molenaar, D, van der Sluis, S, Abbink, T, Altelaar, M, van der Knaap, M S & Bugiani, M 2022, ' Cortical Pathology in Vanishing White Matter ', Cells, vol. 11, no. 22, 3581, pp. 1-19 . https://doi.org/10.3390/cells11223581
Cells, 11(22), 1. Multidisciplinary Digital Publishing Institute (MDPI)
Vanishing white matter (VWM) is classified as a leukodystrophy with astrocytes as primary drivers in its pathogenesis. Magnetic resonance imaging has documented the progressive thinning of cortices in long-surviving patients. Routine histopathologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fecb064340957e0f3d17d0b89014109
https://research.vu.nl/en/publications/1b885d5e-da05-43dd-9050-0a4041dd3d23
https://research.vu.nl/en/publications/1b885d5e-da05-43dd-9050-0a4041dd3d23
Autor:
Sophie Quick, Tessa V. Procter, Jonathan Moss, Luise Seeker, Marc Walton, Angus Lawson, Serena Baker, Anna Beletski, Daniela Jaime Garcia, Mehreen Mohammad, William Mungall, Ami Onishi, Zuzanna Tobola, Michael Stringer, Maurits A. Jansen, Antoine Vallatos, Ylenia Giarratano, Miguel O. Bernabeu, Joanna M. Wardlaw, Anna Williams
Publikováno v:
Quick, S, Procter, T, Moss, J, Seeker, L, Walton, M, Lawson, A, Baker, S, Beletski, A, Jaime Garcia, D, Mohammad, M, Mungall, W, Onishi, A, Tobola, Z, Stringer, M, Jansen, M, Vallatos, A, Giarratano, Y, Bernabeu, M O, Wardlaw, J M & Williams, A C 2022, ' Loss of the heterogeneous expression of flippase ATP11B leads to cerebral small vessel disease in a normotensive rat model ', Acta Neuropathologica, vol. 144, no. 2, pp. 283-303 . https://doi.org/10.1007/s00401-022-02441-4
Cerebral small vessel disease (SVD) is the leading cause of vascular dementia, causes a quarter of strokes, and worsens stroke outcomes. The disease is characterised by patchy cerebral small vessel and white matter pathology, but the underlying mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9b07d7548a989cc06a0f836a7abaac
https://www.pure.ed.ac.uk/ws/files/280682874/ANEU_D_22_00297_R1_1_.pdf
https://www.pure.ed.ac.uk/ws/files/280682874/ANEU_D_22_00297_R1_1_.pdf
Autor:
Jemima J. Burden, Lucy Brooks, Zane Jaunmuktane, Daniela Kocher, Simona Parrinello, Megan Woodberry, Luca Richards, Leila Zakka, Steven M. Pollard, Sebastian Brandner, Melanie Clements, Peter B. Dirks, Michael J. Ellis, Gillian Morrison, Samuel Marguerat, Sara Castro Devesa
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Brooks, L J, Clements, M P, Burden, J J, Kocher, D, Richards, L, Devesa, S C, Zakka, L, Woodberry, M, Ellis, M, Jaunmuktane, Z, Brandner, S, Morrison, G, Pollard, S M, Dirks, P B, Marguerat, S & Parrinello, S 2021, ' The white matter is a pro-differentiative niche for glioblastoma ', Nature Communications, vol. 12, no. 1, pp. 2184 . https://doi.org/10.1038/s41467-021-22225-w
Nature Communications
Brooks, L J, Clements, M P, Burden, J J, Kocher, D, Richards, L, Devesa, S C, Zakka, L, Woodberry, M, Ellis, M, Jaunmuktane, Z, Brandner, S, Morrison, G, Pollard, S M, Dirks, P B, Marguerat, S & Parrinello, S 2021, ' The white matter is a pro-differentiative niche for glioblastoma ', Nature Communications, vol. 12, no. 1, pp. 2184 . https://doi.org/10.1038/s41467-021-22225-w
Nature Communications
Glioblastomas are hierarchically organised tumours driven by glioma stem cells that retain partial differentiation potential. Glioma stem cells are maintained in specialised microenvironments, but whether, or how, they undergo lineage progression out
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c97b883e7b966040527328ba18effa
https://doaj.org/article/1dfd4c8671124520ac4d6ba779864aae
https://doaj.org/article/1dfd4c8671124520ac4d6ba779864aae
Autor:
Johannes A. Hainfellner, Victoria-Elisabeth Gruber, Thomas Czech, Angelika Mühlebner, Martha Feucht, Gregor Kasprian, Theresa Scholl, Lisette Hoogendijk, Eleonora Aronica, Sharon Samueli, Roy J. Reinten, Reinhard Lehner
Publikováno v:
Journal of neuropathology and experimental neurology, 80(3), 274-282. Lippincott Williams and Wilkins
Complex cortical malformations (CCMs), such as hemimegalencephaly and polymicrogyria, are associated with drug-resistant epilepsy and developmental impairment. They share certain neuropathological characteristics including mammalian target of rapamyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7a15c10ecda4c0621df2b7c82896eee
https://doi.org/10.1093/jnen/nlaa159
https://doi.org/10.1093/jnen/nlaa159
Autor:
Sheng-Han Lee, Ta-Fu Chen, Boon Lead Teem, Ching-Chou Hsu, Charles C.-K. Chou, Ming-Jang Chiu, Tsun-Jen Cheng, Kuan-Hung Cho, Li-Wei Kuo, Wan-Ru Zheng
Publikováno v:
Particle and Fibre Toxicology. 19
Background Air pollution, especially fine particulate matter (PM), can cause brain damage, cognitive decline, and an increased risk of neurodegenerative disease, especially alzheimer’s disease (AD). Typical pathological findings of amyloid and tau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a6f61e38aaad03a85d756a071f5aff
https://doi.org/10.1186/s12989-022-00485-8
https://doi.org/10.1186/s12989-022-00485-8