Zobrazeno 1 - 10
of 278
pro vyhledávání: '"MATSUHIKO HAYASHI"'
Autor:
Tsuneo Takenaka, Arif Hasan, Takeshi Marumo, Tsutomu Inoue, Takashi Miyazaki, Hiromichi Suzuki, Yoshifumi Kurosaki, Naohito Ishii, Akira Nishiyama, Matsuhiko Hayashi
Publikováno v:
Kidney & Blood Pressure Research, Pp 1-1 (2023)
Introduction: While recent investigations show that klotho exerts reno-protective actions, it has not been fully addressed whether klotho protein supplementation reverses renal damage. Methods: The impacts of subcutaneous klotho supplementation on ra
Externí odkaz:
https://doaj.org/article/bb794bd802e6476990d5baa2e0a9c81e
Autor:
Toru Hyodo, Masafumi Fukagawa, Nobuhito Hirawa, Matsuhiko Hayashi, Kosaku Nitta, Sovandy Chan, Phanekham Souvannamethy, Minjur Dorji, Chuluuntsetseg Dorj, I. Gde Raka Widiana
Publikováno v:
Renal Replacement Therapy, Vol 5, Iss 1, Pp 1-11 (2019)
Abstract Since 2015, the Committee for International Communication on Academic Research of the Japanese Society for Dialysis Therapy has held its Asian symposium during the society’s Annual Congress to discuss the present status of and demand for d
Externí odkaz:
https://doaj.org/article/62588013a86a4789a70bfbc7b015a4cf
Autor:
Taro Tsujimura, Osamu Takase, Masahiro Yoshikawa, Etsuko Sano, Matsuhiko Hayashi, Kazuto Hoshi, Tsuyoshi Takato, Atsushi Toyoda, Hideyuki Okano, Keiichi Hishikawa
Publikováno v:
eLife, Vol 9 (2020)
While regulation of gene-enhancer interaction is intensively studied, its application remains limited. Here, we reconstituted arrays of CTCF-binding sites and devised a synthetic topological insulator with tetO for chromatin-engineering (STITCH). By
Externí odkaz:
https://doaj.org/article/e842a9a8a27747c1b1211b39efd6f45f
Autor:
Taro Tsujimura, Osamu Takase, Masahiro Yoshikawa, Etsuko Sano, Matsuhiko Hayashi, Tsuyoshi Takato, Atsushi Toyoda, Hideyuki Okano, Keiichi Hishikawa
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-17 (2018)
Abstract Background Contact domains of chromatin serve as a fundamental unit to regulate action of enhancers for target genes. Looping between a pair of CCCTC-binding factor (CTCF)-binding sites in convergent orientations underlies the formation of c
Externí odkaz:
https://doaj.org/article/21d3e1b888ca4dc0b086557c206f7e6d
Autor:
Koshu Okubo, Mako Kamiya, Yasuteru Urano, Hiroshi Nishi, Jan M. Herter, Tanya Mayadas, Daigoro Hirohama, Kazuo Suzuki, Hiroshi Kawakami, Mototsugu Tanaka, Miho Kurosawa, Shinji Kagaya, Keiichi Hishikawa, Masaomi Nangaku, Toshiro Fujita, Matsuhiko Hayashi, Junichi Hirahashi
Publikováno v:
EBioMedicine, Vol 10, Iss C, Pp 204-215 (2016)
Neutrophils are central players in the innate immune system. They generate neutrophil extracellular traps (NETs), which protect against invading pathogens but are also associated with the development of autoimmune and/or inflammatory diseases and thr
Externí odkaz:
https://doaj.org/article/e0ab3864351b42569f8d92f288f0f789
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 11 (2017)
BackgroundHyperphosphatemia is a major factor promoting the formation of arterial medial calcification in chronic kidney disease (CKD). However, arterial medial calcification begins to occur during the early stages of CKD, when hyperphosphatemia is n
Externí odkaz:
https://doaj.org/article/8808fea8d80b4cd3b23ce422b6b638b8
Autor:
Shigeru Shibata, Taiji Furukawa, Maho Yamashita, Matsuhiko Hayashi, Junichi Hirahashi, Yoshihide Fujigaki, Jinping Li, Osamu Yamazaki, George Seki, Tadashi Yoshida, Fumika Ochiai-Homma, Ken Kozuma
Publikováno v:
American Journal of Physiology-Renal Physiology. 321:F771-F784
Electrogenic Na+/[Formula: see text] cotransporter 1-A (NBCe1-A) in the proximal tubule regulates the acid/base balance and fluid volume homeostasis. From the National Center for Biotechnology Information dbSNP database, we identified the I551F varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34ecea85e1b9bae1577b19a74c0f0992
https://doi.org/10.1152/ajprenal.00584.2020
https://doi.org/10.1152/ajprenal.00584.2020
Autor:
Takeshi Marumo, Akira Nishiyama, Arif Ul Hasan, Hiroyuki Kobori, Matsuhiko Hayashi, Tsuneo Takenaka, Naohito Ishii, Hiromichi Suzuki, Tsutomu Inoue, Takashi Miyazaki
Publikováno v:
Journal of Hypertension. 39:1567-1576
Background Klotho interacts with various membrane proteins, such as transforming growth factor-β (TGFβ) and insulin-like growth factor (IGF) receptors. The renal expression of klotho is diminished in chronic kidney disease. Method In this study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f9fb22f7477ee7e089da433e8c8f97
https://doi.org/10.1097/hjh.0000000000002845
https://doi.org/10.1097/hjh.0000000000002845
Autor:
Tsuneo Takenaka, Tsutomu Inoue, Naohito Ishii, Takashi Miyazaki, Hiroyuki Kobori, Akira Nishiyama, Matsuhiko Hayashi, Hiromichi Suzuki
Publikováno v:
American Journal of Physiology-Renal Physiology. 318:F557-F564
Klotho interacts with various membrane proteins such as receptors for transforming growth factor-β (TGF-β) and insulin-like growth factor (IGF). Renal expression of klotho is diminished in polycystic kidney disease (PKD). In the present study, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39a6759b33f3a7fa8c476365a876078
https://doi.org/10.1152/ajprenal.00299.2019
https://doi.org/10.1152/ajprenal.00299.2019
Autor:
Osamu, Yamazaki, Maho, Yamashita, Jinping, Li, Fumika, Ochiai-Homma, Tadashi, Yoshida, Junichi, Hirahashi, Taiji, Furukawa, Ken, Kozuma, Yoshihide, Fujigaki, George, Seki, Matsuhiko, Hayashi, Shigeru, Shibata
Publikováno v:
American journal of physiology. Renal physiology. 321(6)
Homozygous mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5e469996fda7dc1ceb9f2bf29e51b333
https://pubmed.ncbi.nlm.nih.gov/34719949
https://pubmed.ncbi.nlm.nih.gov/34719949