Zobrazeno 1 - 10
of 64
pro vyhledávání: '"MATIAS A AVILA"'
Autor:
Edurne San José-Enériz, Xabier Agirre, Obdulia Rabal, Amaia Vilas-Zornoza, Juan A. Sanchez-Arias, Estibaliz Miranda, Ana Ugarte, Sergio Roa, Bruno Paiva, Ander Estella-Hermoso de Mendoza, Rosa María Alvarez, Noelia Casares, Victor Segura, José I. Martín-Subero, François-Xavier Ogi, Pierre Soule, Clara M. Santiveri, Ramón Campos-Olivas, Giancarlo Castellano, Maite Garcia Fernandez de Barrena, Juan Roberto Rodriguez-Madoz, Maria José García-Barchino, Juan Jose Lasarte, Matias A Avila, Jose Angel Martinez-Climent, Julen Oyarzabal, Felipe Prosper
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Epigenetic drugs are emerging as a powerful therapeutic option for cancer treatment. Here, the authors synthesized selective chemical probes that simultaneously inhibit the G9a and DNMTs methyltransferase activity and demonstrate their anti-tumour ac
Externí odkaz:
https://doaj.org/article/286f3156e84448249eb1c05f274be064
Autor:
Natalia Pydyn, Anna Ferenc, Katarzyna Trzos, Ewelina Pospiech, Mateusz Wilamowski, Olga Mucha, Piotr Major, Justyna Kadluczka, Pedro M. Rodrigues, Jesus M. Banales, Jose M. Herranz, Matias A. Avila, Tomasz Hutsch, Piotr Malczak, Dorota Radkowiak, Andrzej Budzynski, Jolanta Jura, Jerzy Kotlinowski
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 6, Pp 887-906 (2024)
Background & Aims: Hepatic fibrosis is characterized by enhanced deposition of extracellular matrix (ECM), which results from the wound healing response to chronic, repeated injury of any etiology. Upon injury, hepatic stellate cells (HSCs) activate
Externí odkaz:
https://doaj.org/article/a8639a414f0d4d65bfedfeb983af94c3
Autor:
Sofia Lachiondo-Ortega, Claudia M. Rejano-Gordillo, Jorge Simon, Fernando Lopitz-Otsoa, Teresa C. Delgado, Krystyna Mazan-Mamczarz, Naroa Goikoetxea-Usandizaga, L. Estefanía Zapata-Pavas, Ana García-del Río, Pietro Guerra, Patricia Peña-Sanfélix, Natalia Hermán-Sánchez, Ruba Al-Abdulla, Carmen Fernandez-Rodríguez, Mikel Azkargorta, Alejandro Velázquez-Cruz, Joris Guyon, César Martín, Juan Diego Zalamea, Leire Egia-Mendikute, Arantza Sanz-Parra, Marina Serrano-Maciá, Irene González-Recio, Monika Gonzalez-Lopez, Luis Alfonso Martínez-Cruz, Patrizia Pontisso, Ana M. Aransay, Rosa Barrio, James D. Sutherland, Nicola G.A. Abrescia, Félix Elortza, Amaia Lujambio, Jesus M. Banales, Raúl M. Luque, Manuel D. Gahete, Asís Palazón, Matias A. Avila, Jose J. G. Marin, Supriyo De, Thomas Daubon, Antonio Díaz-Quintana, Irene Díaz-Moreno, Myriam Gorospe, Manuel S. Rodríguez, María Luz Martínez-Chantar
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113924- (2024)
Summary: The posttranslational modification of proteins critically influences many biological processes and is a key mechanism that regulates the function of the RNA-binding protein Hu antigen R (HuR), a hub in liver cancer. Here, we show that HuR is
Externí odkaz:
https://doaj.org/article/ac05448b67bf43d08eefd6737eb5e995
Autor:
Sergio Barace, Eva Santamaría, Stefany Infante, Sara Arcelus, Jesus De La Fuente, Enrique Goñi, Ibon Tamayo, Idoia Ochoa, Miguel Sogbe, Bruno Sangro, Mikel Hernaez, Matias A. Avila, Josepmaria Argemi
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 653 (2024)
Whole-tissue transcriptomic analyses have been helpful to characterize molecular subtypes of hepatocellular carcinoma (HCC). Metabolic subtypes of human HCC have been defined, yet whether these different metabolic classes are clinically relevant or d
Externí odkaz:
https://doaj.org/article/849503fa0ca248918b9f5150dce46864
Autor:
Josepmaria Argemi, Maria U. Latasa, Stephen R. Atkinson, Ilya O. Blokhin, Veronica Massey, Joel P. Gue, Joaquin Cabezas, Juan J. Lozano, Derek Van Booven, Aaron Bell, Sheng Cao, Lawrence A. Vernetti, Juan P. Arab, Meritxell Ventura-Cots, Lia R. Edmunds, Constantino Fondevila, Peter Stärkel, Laurent Dubuquoy, Alexandre Louvet, Gemma Odena, Juan L. Gomez, Tomas Aragon, Jose Altamirano, Juan Caballeria, Michael J. Jurczak, D. Lansing Taylor, Carmen Berasain, Claes Wahlestedt, Satdarshan P. Monga, Marsha Y. Morgan, Pau Sancho-Bru, Philippe Mathurin, Shinji Furuya, Carolin Lackner, Ivan Rusyn, Vijay H. Shah, Mark R. Thursz, Jelena Mann, Matias A. Avila, Ramon Bataller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/65a267dd546740ec9b7190c3e67982ab
Autor:
Paula Olaizola, Pui Yuen Lee-Law, Maite G. Fernandez-Barrena, Laura Alvarez, Massimiliano Cadamuro, Mikel Azkargorta, Colm J. O’Rourke, Francisco J. Caballero-Camino, Irene Olaizola, Rocio I.R. Macias, Jose J.G. Marin, Marina Serrano-Maciá, Maria L. Martinez-Chantar, Matias A. Avila, Patricia Aspichueta, Diego F. Calvisi, Matthias Evert, Luca Fabris, Rui E. Castro, Felix Elortza, Jesper B. Andersen, Luis Bujanda, Pedro M. Rodrigues, Maria J. Perugorria, Jesus M. Banales
Publikováno v:
Olaizola, P, Lee-Law, P Y, Fernandez-Barrena, M G, Alvarez, L, Cadamuro, M, Azkargorta, M, O'Rourke, C J, Caballero-Camino, F J, Olaizola, I, Macias, R I R, Marin, J J G, Serrano-Maciá, M, Martinez-Chantar, M L, Avila, M A, Aspichueta, P, Calvisi, D F, Evert, M, Fabris, L, Castro, R E, Elortza, F, Andersen, J B, Bujanda, L, Rodrigues, P M, Perugorria, M J & Banales, J M 2022, ' Targeting NAE1-mediated protein hyper-NEDDylation halts cholangiocarcinogenesis and impacts on tumor-stroma crosstalk in experimental models ', Journal of Hepatology, vol. 77, no. 1, pp. 177-190 . https://doi.org/10.1016/j.jhep.2022.02.007
Addi. Archivo Digital para la Docencia y la Investigación
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Addi. Archivo Digital para la Docencia y la Investigación
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[EN] BACKGROUND & AIMS: Cholangiocarcinoma (CCA) comprises a heterogeneous group of malignant tumors associated with dismal prognosis. Alterations in post-translational modifications (PTMs), including NEDDylation, result in abnormal protein dynamics,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc951961d3c4bc25aa43db66243e451
https://doi.org/10.1016/j.jhep.2022.02.007
https://doi.org/10.1016/j.jhep.2022.02.007
Multiple seasonalities often appear in high-frequency data. In this context multiple seasonal components are usually modelled in a deterministic way by trigonometric functions or dummy variables. This assumption may be too strict. Instead, a more fle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89f08e47b54a8749160fe6b50be74ab3
https://doi.org/10.21203/rs.3.rs-2860239/v1
https://doi.org/10.21203/rs.3.rs-2860239/v1
Autor:
Ruben Hernaez, MATIAS A AVILA
Publikováno v:
Gut. 72:7-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d568fd28dddc8057db9938ba7748f83
https://doi.org/10.1136/gutjnl-2022-327132
https://doi.org/10.1136/gutjnl-2022-327132
Autor:
Christopher Ledford, Ryan R. Dehoff, V. M. Miller, Christopher Rock, Tim Horn, Harvey West, Matias Garcia-Avila, Mark Pankow
Publikováno v:
Metallurgical and Materials Transactions B. 52:676-688
Gas-atomized nickel alloy ATI 718™ powders with a nominal particle distribution of 15 to 45 µm were used in a laser powder bed fusion (LPBF) additive manufacturing (AM) process for ten sequential builds without refreshing with new powder. The repe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d737b6bd4933b1926072f42fa704ae50
https://doi.org/10.1007/s11663-020-02040-2
https://doi.org/10.1007/s11663-020-02040-2
Autor:
Leticia Colyn, Gloria Alvarez-Sola, M. Ujue Latasa, Iker Uriarte, Jose M. Herranz, Maria Arechederra, George Vlachogiannis, Colin Rae, Antonio Pineda-Lucena, Andrea Casadei-Gardini, Federica Pedica, Luca Aldrighetti, Angeles López-López, Angeles López-Gonzálvez, Coral Barbas, Sergio Ciordia, Sebastiaan M. Van Liempd, Juan M. Falcón-Pérez, Jesus Urman, Bruno Sangro, Silve Vicent, Maria J. Iraburu, Felipe Prosper, Leonard J. Nelson, Jesus M. Banales, Maria Luz Martinez-Chantar, Jose J. G. Marin, Chiara Braconi, Christian Trautwein, Fernando J. Corrales, F. Javier Cubero, Carmen Berasain, Maite G. Fernandez-Barrena, Matias A. Avila
Publikováno v:
Journal of experimental & clinical cancer research 41, 183 (2022). doi:10.1186/s13046-022-02386-2
J Exp Clin Cancer Res.
J Exp Clin Cancer Res.
Journal of experimental & clinical cancer research 41, 183 (2022). doi:10.1186/s13046-022-02386-2
Published by Springer, Berlin ; Heidelberg
Published by Springer, Berlin ; Heidelberg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6c46428d16570219a805fadcba88f7
https://pubmed.ncbi.nlm.nih.gov/35619118
https://pubmed.ncbi.nlm.nih.gov/35619118