Zobrazeno 1 - 10
of 177
pro vyhledávání: '"MATHIAS UHLEN"'
Autor:
Sunjae Lee, Victoria Meslier, Gholamreza Bidkhori, Fernando Garcia-Guevara, Lucie Etienne-Mesmin, Frederick Clasen, Junseok Park, Florian Plaza Oñate, Haizhuang Cai, Emmanuelle Le Chatelier, Nicolas Pons, Marcela Pereira, Maike Seifert, Fredrik Boulund, Lars Engstrand, Doheon Lee, Gordon Proctor, Adil Mardinoglu, Stéphanie Blanquet-Diot, David Moyes, Mathieu Almeida, S. Dusko Ehrlich, Mathias Uhlen, Saeed Shoaie
Publikováno v:
npj Biofilms and Microbiomes, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract Species composition of the healthy adult gut microbiota tends to be stable over time. Destabilization of the gut microbiome under the influence of different factors is the main driver of the microbial dysbiosis and subsequent impacts on host
Externí odkaz:
https://doaj.org/article/a887eb4803374d36b77690db31148648
Autor:
Bouchra Ezzamouri, Dorines Rosario, Gholamreza Bidkhori, Sunjae Lee, Mathias Uhlen, Saeed Shoaie
Publikováno v:
npj Systems Biology and Applications, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract The human gut microbiome has been associated with several metabolic disorders including type 2 diabetes mellitus. Understanding metabolic changes in the gut microbiome is important to elucidate the role of gut bacteria in regulating host met
Externí odkaz:
https://doaj.org/article/89849651f01544f3b2f52806c5993f83
Autor:
Neelu Begum, Sunjae Lee, Theo John Portlock, Aize Pellon, Shervin Dokht Sadeghi Nasab, Jens Nielsen, Mathias Uhlen, David L. Moyes, Saeed Shoaie
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Metabolic differences between Candida species are uncovered using the BioFung database alongside genomic and metabolic analysis.
Externí odkaz:
https://doaj.org/article/ed773267446344fa9204e94dfdd48fed
Autor:
Fei Wang, Peiwen Ding, Xue Liang, Xiangning Ding, Camilla Blunk Brandt, Evelina Sjöstedt, Jiacheng Zhu, Saga Bolund, Lijing Zhang, Laura P. M. H. de Rooij, Lihua Luo, Yanan Wei, Wandong Zhao, Zhiyuan Lv, János Haskó, Runchu Li, Qiuyu Qin, Yi Jia, Wendi Wu, Yuting Yuan, Mingyi Pu, Haoyu Wang, Aiping Wu, Lin Xie, Ping Liu, Fang Chen, Jacqueline Herold, Joanna Kalucka, Max Karlsson, Xiuqing Zhang, Rikke Bek Helmig, Linn Fagerberg, Cecilia Lindskog, Fredrik Pontén, Mathias Uhlen, Lars Bolund, Niels Jessen, Hui Jiang, Xun Xu, Huanming Yang, Peter Carmeliet, Jan Mulder, Dongsheng Chen, Lin Lin, Yonglun Luo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Pigs are important large animal models for biomedical research. Here, the authors construct a single-cell landscape of pig tissues, unravelling the phenotypic heterogeneity of blood endothelial cells in adipose tissues and the evolutionally conserved
Externí odkaz:
https://doaj.org/article/c21d50994fe24c6aa783a0e4f2146142
Autor:
Max Karlsson, Evelina Sjöstedt, Per Oksvold, Åsa Sivertsson, Jinrong Huang, María Bueno Álvez, Muhammad Arif, Xiangyu Li, Lin Lin, Jiaying Yu, Tao Ma, Fengping Xu, Peng Han, Hui Jiang, Adil Mardinoglu, Cheng Zhang, Kalle von Feilitzen, Xun Xu, Jian Wang, Huanming Yang, Lars Bolund, Wen Zhong, Linn Fagerberg, Cecilia Lindskog, Fredrik Pontén, Jan Mulder, Yonglun Luo, Mathias Uhlen
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background There is a need for functional genome-wide annotation of the protein-coding genes to get a deeper understanding of mammalian biology. Here, a new annotation strategy is introduced based on dimensionality reduction and density-base
Externí odkaz:
https://doaj.org/article/1a4c2eb074664d69abac78894b05f1bc
Publikováno v:
Gut Microbes, Vol 14, Iss 1 (2022)
Fungal communities (mycobiome) have an important role in sustaining the resilience of complex microbial communities and maintenance of homeostasis. The mycobiome remains relatively unexplored compared to the bacteriome despite increasing evidence hig
Externí odkaz:
https://doaj.org/article/bb285fef3efa469dbc6ffcb6d20e50a2
Autor:
Cheng Zhang, Mengnan Shi, Woonghee Kim, Muhammad Arif, Martina Klevstig, Xiangyu Li, Hong Yang, Cemil Bayram, Ismail Bolat, Özlem Özdemir Tozlu, Ahmet Hacımuftuoglu, Serkan Yıldırım, Jihad Sebhaoui, Shazia Iqbal, Yongjun Wei, Xiaojing Shi, Jens Nielsen, Hasan Turkez, Mathias Uhlen, Jan Boren, Adil Mardinoglu
Publikováno v:
EBioMedicine, Vol 83, Iss , Pp 104214- (2022)
Summary: Background: Non-alcoholic fatty liver disease (NAFLD) encompasses a wide spectrum of liver pathologies. However, no medical treatment has been approved for the treatment of NAFLD. In our previous study, we found that PKLR could be a potentia
Externí odkaz:
https://doaj.org/article/36818a6a57cf492cbc5540d8d174de87
Autor:
Ceri Proffitt, Gholamreza Bidkhori, Sunjae Lee, Abdellah Tebani, Adil Mardinoglu, Mathias Uhlen, David L. Moyes, Saeed Shoaie
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104513- (2022)
Summary: The human gut microbiome has been associated with metabolic disorders including obesity, type 2 diabetes, and atherosclerosis. Understanding the contribution of microbiome metabolic changes is important for elucidating the role of gut bacter
Externí odkaz:
https://doaj.org/article/1218c72e51e849f2b695c26beafefd83
Autor:
Umberto Maria Battisti, Leticia Monjas, Fady Akladios, Josipa Matic, Eric Andresen, Carolin H. Nagel, Malin Hagkvist, Liliana Håversen, Woonghee Kim, Mathias Uhlen, Jan Borén, Adil Mardinoğlu, Morten Grøtli
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 668 (2023)
The inhibition of liver pyruvate kinase could be beneficial to halt or reverse non-alcoholic fatty liver disease (NAFLD), a progressive accumulation of fat in the liver that can lead eventually to cirrhosis. Recently, urolithin C has been reported as
Externí odkaz:
https://doaj.org/article/030b7f82a2c046bcb5af2aeb60b25820
Autor:
Fei Wang, Peiwen Ding, Xue Liang, Xiangning Ding, Camilla Blunk Brandt, Evelina Sjöstedt, Jiacheng Zhu, Saga Bolund, Lijing Zhang, Laura P. M. H. de Rooij, Lihua Luo, Yanan Wei, Wandong Zhao, Zhiyuan Lv, János Haskó, Runchu Li, Qiuyu Qin, Yi Jia, Wendi Wu, Yuting Yuan, Mingyi Pu, Haoyu Wang, Aiping Wu, Lin Xie, Ping Liu, Fang Chen, Jacqueline Herold, Joanna Kalucka, Max Karlsson, Xiuqing Zhang, Rikke Bek Helmig, Linn Fagerberg, Cecilia Lindskog, Fredrik Pontén, Mathias Uhlen, Lars Bolund, Niels Jessen, Hui Jiang, Xun Xu, Huanming Yang, Peter Carmeliet, Jan Mulder, Dongsheng Chen, Lin Lin, Yonglun Luo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/d4cf4c7a7e6b438db4f2246d1eed4075