Dual stimulation by autoantigen and CpG fosters the proliferation of exhausted rheumatoid factor-specific CD21low B cells in hepatitis C virus-cured mixed cryoglobulinemia

Autor: Martina Del Padre, Ramona Marrapodi, Ylenia A. Minafò, Eva Piano Mortari, Giovanna Radicchio, Chiara Bocci, Laura Gragnani, Alessandro Camponeschi, Stefania Colantuono, Lucia Stefanini, Stefania Basili, Rita Carsetti, Massimo Fiorilli, Milvia Casato, Marcella Visentini

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

IntroductionHepatitis C virus (HCV) causes mixed cryoglobulinemia (MC) by driving clonal expansion of B cells expressing B cell receptors (BCRs), often encoded by the VH1-69 variable gene, endowed with both rheumatoid factor (RF) and anti-HCV specifi

Externí odkaz: https://doaj.org/article/d49f38d62d5f405ca13c841ecf93fe1c

The Sex-Specific Detrimental Effect of Diabetes and Gender-Related Factors on Pre-admission Medication Adherence Among Patients Hospitalized for Ischemic Heart Disease: Insights From EVA Study

Autor: Valeria Raparelli, Marco Proietti, Giulio Francesco Romiti, Andrea Lenzi, Stefania Basili, The EVA Collaborative Group, Claudio Tiberti, Federica Panimolle, Andrea Isidori, Elisa Giannetta, Mary Anna Venneri, Laura Napoleone, Marta Novo, Silvia Quattrino, Simona Ceccarelli, Eleni Anastasiadou, Francesca Megiorni, Cinzia Marchese, Enrico Mangieri, Gaetano Tanzilli, Nicola Viceconte, Francesco Barillà, Carlo Gaudio, Vincenzo Paravati, Guglielmo Tellan, Evaristo Ettorre, Adriana Servello, Fabio Miraldi, Andrea Moretti, Alessandra Tanzilli, Piergiovanni Mazzonna, Suleyman Al Kindy, Riccardo Iorio, Martina Di Iorio, Gennaro Petriello, Laura Gioffrè, Eleonora Indolfi, Gaetano Pero, Nino Cocco, Loredana Iannetta, Sara Giannuzzi, Emilio Centaro, Sonia Cristina Sergi, Filippo Toriello, Eleonora Ruscio, Tommaso Todisco, Nicolò Sperduti, Giuseppe Santangelo, Giacomo Visioli, Marco Vano, Marco Borgi, Ludovica Maria Antonini, Silvia Robuffo, Claudia Tucci, Agostino Rossoni, Valeria Spugnardi, Annarita Vernile, Mariateresa Santoliquido, Verdiana Santori, Giulia Tosti, Fabrizio Recchia, Francesco Morricone, Roberto Scacciavillani, Alice Lipari, Andrea Zito, Floriana Testa, Giulia Ricci, Ilaria Vellucci, Marianna Vincenti, Silvia Pietropaolo, Camilla Scala, Nicolò Rubini, Marta Tomassi, Daria Amoroso, Lucia Stefanini, Simona Bartimoccia, Giovanni Talerico, Pasquale Pignatelli, Roberto Cangemi, Salvatore Minisola, Sergio Morelli, Antonio Fraioli, Silvia Nocchi, Mario Fontana, Sebastiano Filetti, Massimo Fiorilli, Danilo Toni, Anne Falcou, Louise Pilote, Tabeth Tsitsi Jiri, Muhammad Ahmer Wali, Amanpreet Kaur, Malik Elharram, Anna Rita Vestri, Patrizia Ferroni, Clara Crescioli, Cristina Antinozzi, Francesca Serena Pignataro, Tiziana Bellini, Alessandro Trentini, Roberto Carnevale, Cristina Nocella, Carlo Catalano, Iacopo Carbone, Nicola Galea, Giuliano Bertazzoni, Marianna Suppa, Antonello Rosa, Gioacchino Galardo, Maria Alessandroni, Lorena Cipollone, Alessandro Coppola, Mariangela Palladino, Giulio Illuminati, Fabrizio Consorti, Paola Mariani, Fabrizio Neri, Paolo Salis, Antonio Segatori, Laurent Tellini, Gianluca Costabile

Publikováno v: Frontiers in Endocrinology, Vol 10 (2019)

Background: Sex and gender-related factors have been under-investigated as relevant determinants of health outcomes across non-communicable chronic diseases. Poor medication adherence results in adverse clinical outcomes and sex differences have been

Externí odkaz: https://doaj.org/article/4ae1451f249f4c12b6d5178d6535b92b

Correction to: Management of mixed cryoglobulinemia with rituximab: evidence and consensus-based recommendations from the Italian Study Group of Cryoglobulinemia (GISC)

Autor: Luca Quartuccio, Alessandra Bortoluzzi, Carlo Alberto Scirè, Antonio Marangoni, Giulia Del Frate, Elena Treppo, Laura Castelnovo, Francesco Saccardo, Roberta Zani, Marco Candela, Paolo Fraticelli, Cesare Mazzaro, Piero Renoldi, Patrizia Scaini, Davide Antonio Filippini, Marcella Visentini, Salvatore Scarpato, Dilia Giuggioli, Maria Teresa Mascia, Marco Sebastiani, Anna Linda Zignego, Gianfranco Lauletta, Massimo Fiorilli, Milvia Casato, Clodoveo Ferri, Maurizio Pietrogrande, Pietro Enrico Pioltelli, Salvatore De Vita, Giuseppe Monti, Massimo Galli

Publikováno v: Clinical Rheumatology. 42:641-642

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::55506befcb2e628bb4c29693e21964cd
https://doi.org/10.1007/s10067-022-06414-6

Flares of mixed cryoglobulinaemia vasculitis after vaccination against SARS-CoV-2

Autor: Lucia Stefanini, Anna Linda Zignego, Luisa Petraccia, Milvia Casato, Stefania Basili, Francesca La Gualana, Silvia Marri, Clodoveo Ferri, Massimo Fiorilli, Serena Lorini, Marcella Visentini, Stefano Angelo Santini, Laura Gragnani, Francesco Madia, Andrea Palladino, T. Urraro, Monica Monti, Annalisa Villa

Studies on the safety and immunogenicity of SARS-CoV-2 vaccination in patients with inflammatory rheumatic diseases have so far not included mixed cryoglobulinaemia (MC) vasculitis.1–3 We report a prospective observational multicentre study on this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f68397d31ac8d2ed847797be8f906f
http://hdl.handle.net/11573/1593424

Clinico-immunological outcomes of HCV-cured cryoglobulinemia: Lower relapse rate with interferon-based than interferon-free therapy

Autor: Martina Del Padre, Giulia Garzi, Stefania Colantuono, Stefania Basili, Marcella Visentini, Massimo Fiorilli, Adriano De Santis, Milvia Casato, Giulia Collalti, Ramona Marrapodi

Publikováno v: Liver international : official journal of the International Association for the Study of the LiverREFERENCES. 41(1)

Sustained virological response (SVR) obtained with interferon (IFN) or with direct-acting antivirals (DAAs) is commonly followed by response of hepatitis C virus (HCV)-associated mixed cryoglobulinemia vasculitis (MCV), but relapse of MCV despite SVR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1759f2324bd277ea01a299a0a3943a2
https://pubmed.ncbi.nlm.nih.gov/33064930