Zobrazeno 1 - 10
of 68
pro vyhledávání: '"MASH-1"'
Publikováno v:
Neural Regeneration Research
To date, it remains poorly understood whether astrocytes can be easily reprogrammed into neurons. Mash1 and Brn2 have been previously shown to cooperate to reprogram fibroblasts into neurons. In this study, we examined astrocytes from 2-month-old Spr
Autor:
Phillip R. Kramer, Susan Wray
Publikováno v:
Developmental Biology. 227:343-357
Neurons differentiating into the luteinizing hormone-releasing hormone (LHRH) neuroendocrine phenotype are derived from the nasal placode. Cells within the vomeronasal organ anlage that turn on LHRH gene and peptide expression subsequently migrate in
Autor:
Katrin Huber
Publikováno v:
Developmental Biology. 298(2):335-343
During the past years considerable progress has been made in understanding the generation of cell diversity in the neural crest (NC). Sympathoadrenal (SA) cells constitute a major lineage among NC derivatives; they give rise to sympathetic neurons, n
Publikováno v:
Developmental Biology. 279(2):501-508
Phox2B, a homeodomain transcription factor closely related to Phox2A, is expressed in peripheral and central noradrenergic neurons. In neural crest (NC) derivatives Phox2B is restricted to sympathetic and parasympathetic ganglia, enteric neurons, and
Publikováno v:
Neuroscience. 130:95-105
Genetic mutations affecting signaling by glial cell line-derived neurotrophic factor (GDNF) perturb development of breathing in mice and are associated with congenital central hypoventilation syndrome in humans. However, the role of GDNF in developme
Autor:
Håkan Axelson
Publikováno v:
Cancer Letters. 204:171-178
Neuroblastoma is a childhood tumor originating from cells of the developing sympathetic nervous system. The disease exhibits a remarkable phenotypic diversity reflected in the outcome, ranging from spontaneous regression to fatal disease. Mammalian a
Autor:
Sharon Wilton, Ilona S. Skerjanc
Publikováno v:
FEBS Letters. 472:53-56
MEF2C is a transcription factor expressed in neural lineages. After transient transfection, the MEF2 family of factors can act synergistically with the neural-specific transcription factor, MASH-1, and activate exogenous neural-specific promoters. To
Requirement of the MASH-1 transcription factor for neuroendocrine differentiation of thyroid C cells
Publikováno v:
Journal of Neurobiology. 34:126-134
Thyroid C cells are neural crest-derived neuroendocrine cells that can acquire features similar to serotonergic neurons. Based on developmental and phenotypic markers, we have previously proposed that C cells and serotonergic enteric neurons arise fr
Autor:
Virginia M. Tennyson, Tuan Duc Pham, E. Blaugrund, Michael D. Gershon, L. Lo, D.J. Anderson, Lukas Sommer
Publikováno v:
Development. 122:309-320
Enteric and sympathetic neurons have previously been proposed to be lineally related. We present independent lines of evidence that suggest that enteric neurons arise from at least two lineages, only one of which expresses markers in common with symp
Autor:
Yuko Suzuki
Publikováno v:
Chemical senses. 30
Non-sensory patches in the posterior dorsal fossa of the rodent nasal cavity are formed between postnatal (P) days 10 and 21 due to programmed death of ORNs and GBCs (Suzuki et al., 2000). In a previous study, we found bHLH transcription factors Hes6